The new gravity field models of gravity field and steady-state ocean circulation explorer(GOCE),TIM_R6 and DIR_R6,were released by the European Space Agency(ESA)in June 2019.The sixth generation of gravity models have...The new gravity field models of gravity field and steady-state ocean circulation explorer(GOCE),TIM_R6 and DIR_R6,were released by the European Space Agency(ESA)in June 2019.The sixth generation of gravity models have the highest possible signal and lowest error levels compared with other GOCE-only gravity models,and the accuracy is significantly improved.This is an opportunity to build high precision geostrophic currents.The mean dynamic topography and geostrophic currents have been calculated by the 5th(TIM_R5 and DIR_R5),6th(TIM_R6 and DIR_R6)release of GOCE gravity field models and ITSG-Grace2018 of GRACE gravity field model in this study.By comparison with the drifter results,the optimal filtering lengths of them have been obtained(for DIR_R5,DIR_R6,TIM_R5 and TIM_R6 models are 1°and for ITSG-Grace2018 model is 1.1°).The filtered results show that the geostrophic currents obtained by the GOCE gravity field models can better reflect detailed characteristics of ocean currents.The total geostrophic speed based on the TIM_R6 model is similar to the result of the DIR_R6 model with standard deviation(STD)of 0.320 m/s and 0.321 m/s,respectively.The STD of the total velocities are 0.333 m/s and 0.325 m/s for DIR_R5 and TIM_R5.When compared with ITSG-Grace2018 results,the STD(0.344 m/s)of total geostrophic speeds is larger than GOCE results,and the accuracy of geostrophic currents obtained by ITSG-Grace2018 is lower.And the absolute errors are mainly distributed in the areas with faster speeds,such as the Antarctic circumpolar circulation,equatorial region,Kuroshio and Gulf Stream areas.After the remove-restore technique was applied to TIM_R6 MDT,the STD of total geostrophic speeds dropped to 0.162 m/s.展开更多
【目的】开展拉鲁湿地水体酵母菌多样性研究,探究理化因子与酵母菌群落结构的相互关系。【方法】采用原位培养法从拉鲁湿地11个水样中分离酵母菌,应用26S r RNA D1/D2区域序列分析,并结合经典分类法对获得的菌株进行分类鉴定,运用SPSS和...【目的】开展拉鲁湿地水体酵母菌多样性研究,探究理化因子与酵母菌群落结构的相互关系。【方法】采用原位培养法从拉鲁湿地11个水样中分离酵母菌,应用26S r RNA D1/D2区域序列分析,并结合经典分类法对获得的菌株进行分类鉴定,运用SPSS和CANOCO软件分析酵母菌多样性及其与环境因子相关性。【结果】从拉鲁湿地水体中分离得到169株酵母菌,鉴定分属为15个属31个种。优势种为Ustilentyloma graminis和Filobasidium magnum,优势属为Naganishia、Ustilentyloma、Filobasidium和Cystofibasidium。统计分析结果表明,化学需氧量(COD)是影响拉鲁湿地水体酵母菌数量的显著因素,另外,此理化因子是影响Ustilentyloma分布的重要环境条件。【结论】西藏拉鲁湿地酵母菌资源比较丰富,且存在明显的空间异质性。展开更多
目的探讨新型冠状病毒(简称新冠病毒)感染新生儿的临床特点及不同临床分型之间的差异。方法回顾性分析广西壮族自治区妇幼保健院新生儿病房2022年12月11日至2023年1月10日确诊新冠病毒感染新生儿的病例资料,根据临床表现分为轻症组(包...目的探讨新型冠状病毒(简称新冠病毒)感染新生儿的临床特点及不同临床分型之间的差异。方法回顾性分析广西壮族自治区妇幼保健院新生儿病房2022年12月11日至2023年1月10日确诊新冠病毒感染新生儿的病例资料,根据临床表现分为轻症组(包括无症状感染、轻型、普通型)和重症组(包括重型、危重型),比较不同组别的临床特征。结果共纳入162例新冠病毒感染患儿,男性91例(56.2%),早产儿27例(16.7%),低出生体重儿26例(16.0%)。发病日龄15(8,21)d,发病日龄>7 d 125例(77.2%),常见临床表现包括发热(79.0%)、咳嗽(59.3%)、鼻塞(42.6%),血常规异常70例(43.2%),以中性粒细胞减少多见。轻症组136例(84.0%),重症组26例(16.0%)。轻症组最常见的临床表现为发热(79.4%),重症组为发绀(92.3%)。与轻症组相比,重症组男性、早产儿、低出生体重儿、反应差比例更高,发热持续时间更长,差异有统计学意义(P<0.05)。两组血常规异常率差异无统计学意义(P>0.05)。60.6%(77/127)患儿胸部X线片提示肺炎。157例治愈或好转出院,住院时间5(3,6)d;5例自动出院。结论新生儿新冠病毒感染以轻型、普通型为主,临床症状轻,发热常见;少数为重型或危重型,发绀最常见;反应差、发热时间长者需警惕重型可能,尤其是男婴、早产儿及低出生体重儿。多数患儿近期预后良好。展开更多
In an investigation of blood-sucking insects and arboviruses, a virus(YN12243) was isolated from Culicoides samples collected in the Sino-Burmese border region of Yunnan Province, China. The virus caused cytopathic ef...In an investigation of blood-sucking insects and arboviruses, a virus(YN12243) was isolated from Culicoides samples collected in the Sino-Burmese border region of Yunnan Province, China. The virus caused cytopathic effect(CPE) in C6/36 cells and passaged stably. Polyacrylamide gel analysis showed that the genome of YN12243 was composed of 12 segments of double-stranded RNA(dsRNA), with a distribution pattern of 6-6. The nucleotide and amino acid sequences of the coding region(1.12 segments) were17,803 bp and 5,925 amino acids in length, respectively. The phylogenetic analysis of VP1 protein(RdRp) revealed that YN12243 belonged to genus Seadornavirus of family Reoviridae, and further analysis indicated that YN12243 belongs to the Banna virus(BAV) genotype A2. Additionally, YN12243 was located in the same evolutionary cluster as BAV strains isolated from different mosquito species, suggesting that the BAV isolated from Culicoides does not have species barriers. These results indicate that Culicoides can also be a vector for BAV. In view of the hematophagous habits of Culicoides on cattle, horses, deer, and other large animals, as well as the possibility of spreading and causing a variety of animal arboviral diseases, it is important to improve infection detection and monitor the BAV in large livestock.展开更多
Dear Editor,The genus Orbivirus,within the family Reoviridae,includes 22 virus species(King et al.,2011).They are distributed globally,but are particularly prevalent in Europe,Asia,and Africa.In addition,they can be t...Dear Editor,The genus Orbivirus,within the family Reoviridae,includes 22 virus species(King et al.,2011).They are distributed globally,but are particularly prevalent in Europe,Asia,and Africa.In addition,they can be transmitted by ticks or other hematophagous insect vectors,including Culicoides,mosquitoes,and sandflies(Belaga-展开更多
Dear Editor,The family Totiviridae contains non-enveloped,doublestranded RNA viruses with genomes of approximately 4.6–7 kbp in length.These totiviruses are classified into five genera:Totivirus,Victorivirus,Trichomo...Dear Editor,The family Totiviridae contains non-enveloped,doublestranded RNA viruses with genomes of approximately 4.6–7 kbp in length.These totiviruses are classified into five genera:Totivirus,Victorivirus,Trichomonasvirus,Giardiavirus,and Leishmaniavirus(Nibert 2007).They are associated with latent infections of fungal or protozoan hosts(Li et al.2020).Recently,a few totiviruses have been identified and shown to have unexpected host distributions,including insects,plants.展开更多
Selective removal of ultra-high low-density lipoprotein(LDL)from the blood of hyperlipemia patients using hemoperfusion is considered an efficient method to prevent the deterioration of atherosclerotic cardiovascular ...Selective removal of ultra-high low-density lipoprotein(LDL)from the blood of hyperlipemia patients using hemoperfusion is considered an efficient method to prevent the deterioration of atherosclerotic cardiovascular disease.Based on the exceptional structure–function properties of multistimulus-responsive materials,we developed a magnetic photorenewable nanoadsorbent(Fe_(3)O_(4)@SiO_(2)@Azo-COOH)with outstanding selectivity and regenerative characteristics,featuring functionalized azobenzene as the ligand.The dual-stimulus response endowed Fe_(3)O_(4)@SiO_(2)@Azo-COOH with rapid separation and photoregenerative properties.The adsorbent demonstrated excellent removal efficiency of LDL with an adsorption capacity of 15.06 mg/g,and highly repetitive adsorption performance(≥5 cycles)under irradiation.Fe_(3)O_(4)@SiO_(2)@Azo-COOH also exhibited remarkable adsorption properties and selectivity in human serum,with adsorption capacities of 10.93,21.26 and 9.80 mg/g for LDL,total cholesterol and triglycerides and only 0.77 mg/g for high-density lipoprotein(HDL),resulting in a 93%selective adsorption difference(LDL/HDL).Complete green regeneration of the nanoadsorbent was achieved through a simple regeneration process,maintaining a recovery rate of 99.4%after five regeneration experiments.By combining dynamic perfusion experiment with micromagnetic microfluidics,the LDL content decreased by 16.6%.Due to its superior adsorption capacity and regenerative properties,the dual stimulus-responsive nanosorbent is considered a potential hemoperfusion adsorbent.展开更多
基金The Open Fund of Key Laboratory of Marine Environmental Information Technologythe Open Foundation of Technology Innovation Center for Marine Information,Ministry of Natural Resources+7 种基金the Liao Ning Revitalization Talents Program under contract No.XLYC1807161the Dalian High-level Talents Innovation Support Plan under contract No.2017RQ063the National Natural Science Foundation of China under contract Nos 41206013 and 41430963the Scientific Research Project of Liaoning Province Department of Education under contract No.QL201905the Projects of Institute of Marine Industry Technology of Liaoning Universitiesthe grant from Key R&D Program of Liaoning Province under contract No.2019JH2/10200015the Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)under contract No.GML2019ZD0402the Shandong Provincial Key Research and Development Program(SPKR&DP)under contract No.2019JZZY020713.
文摘The new gravity field models of gravity field and steady-state ocean circulation explorer(GOCE),TIM_R6 and DIR_R6,were released by the European Space Agency(ESA)in June 2019.The sixth generation of gravity models have the highest possible signal and lowest error levels compared with other GOCE-only gravity models,and the accuracy is significantly improved.This is an opportunity to build high precision geostrophic currents.The mean dynamic topography and geostrophic currents have been calculated by the 5th(TIM_R5 and DIR_R5),6th(TIM_R6 and DIR_R6)release of GOCE gravity field models and ITSG-Grace2018 of GRACE gravity field model in this study.By comparison with the drifter results,the optimal filtering lengths of them have been obtained(for DIR_R5,DIR_R6,TIM_R5 and TIM_R6 models are 1°and for ITSG-Grace2018 model is 1.1°).The filtered results show that the geostrophic currents obtained by the GOCE gravity field models can better reflect detailed characteristics of ocean currents.The total geostrophic speed based on the TIM_R6 model is similar to the result of the DIR_R6 model with standard deviation(STD)of 0.320 m/s and 0.321 m/s,respectively.The STD of the total velocities are 0.333 m/s and 0.325 m/s for DIR_R5 and TIM_R5.When compared with ITSG-Grace2018 results,the STD(0.344 m/s)of total geostrophic speeds is larger than GOCE results,and the accuracy of geostrophic currents obtained by ITSG-Grace2018 is lower.And the absolute errors are mainly distributed in the areas with faster speeds,such as the Antarctic circumpolar circulation,equatorial region,Kuroshio and Gulf Stream areas.After the remove-restore technique was applied to TIM_R6 MDT,the STD of total geostrophic speeds dropped to 0.162 m/s.
文摘目的探讨新型冠状病毒(简称新冠病毒)感染新生儿的临床特点及不同临床分型之间的差异。方法回顾性分析广西壮族自治区妇幼保健院新生儿病房2022年12月11日至2023年1月10日确诊新冠病毒感染新生儿的病例资料,根据临床表现分为轻症组(包括无症状感染、轻型、普通型)和重症组(包括重型、危重型),比较不同组别的临床特征。结果共纳入162例新冠病毒感染患儿,男性91例(56.2%),早产儿27例(16.7%),低出生体重儿26例(16.0%)。发病日龄15(8,21)d,发病日龄>7 d 125例(77.2%),常见临床表现包括发热(79.0%)、咳嗽(59.3%)、鼻塞(42.6%),血常规异常70例(43.2%),以中性粒细胞减少多见。轻症组136例(84.0%),重症组26例(16.0%)。轻症组最常见的临床表现为发热(79.4%),重症组为发绀(92.3%)。与轻症组相比,重症组男性、早产儿、低出生体重儿、反应差比例更高,发热持续时间更长,差异有统计学意义(P<0.05)。两组血常规异常率差异无统计学意义(P>0.05)。60.6%(77/127)患儿胸部X线片提示肺炎。157例治愈或好转出院,住院时间5(3,6)d;5例自动出院。结论新生儿新冠病毒感染以轻型、普通型为主,临床症状轻,发热常见;少数为重型或危重型,发绀最常见;反应差、发热时间长者需警惕重型可能,尤其是男婴、早产儿及低出生体重儿。多数患儿近期预后良好。
基金supported by the National Natural Science Foundation of China(81290342,81501757)the Special National Project on Research and Development of Key Biosafety Technologies(2016YFC1201904)+1 种基金the National Key Plan for Scientific Research and Development of China(2016YFD0500300)the development grants of State Key Laboratory of Infectious Disease Prevention and Control(2014SKLID103,2015SKLID505)
文摘In an investigation of blood-sucking insects and arboviruses, a virus(YN12243) was isolated from Culicoides samples collected in the Sino-Burmese border region of Yunnan Province, China. The virus caused cytopathic effect(CPE) in C6/36 cells and passaged stably. Polyacrylamide gel analysis showed that the genome of YN12243 was composed of 12 segments of double-stranded RNA(dsRNA), with a distribution pattern of 6-6. The nucleotide and amino acid sequences of the coding region(1.12 segments) were17,803 bp and 5,925 amino acids in length, respectively. The phylogenetic analysis of VP1 protein(RdRp) revealed that YN12243 belonged to genus Seadornavirus of family Reoviridae, and further analysis indicated that YN12243 belongs to the Banna virus(BAV) genotype A2. Additionally, YN12243 was located in the same evolutionary cluster as BAV strains isolated from different mosquito species, suggesting that the BAV isolated from Culicoides does not have species barriers. These results indicate that Culicoides can also be a vector for BAV. In view of the hematophagous habits of Culicoides on cattle, horses, deer, and other large animals, as well as the possibility of spreading and causing a variety of animal arboviral diseases, it is important to improve infection detection and monitor the BAV in large livestock.
基金supported by a grant from the China MegaProject on Infectious Disease Prevention(grant numbers 2013ZX10004-605,2013ZX10004-607,2013ZX10004-217,and 2011ZX10004-001)the National Hi-Tech Research and Development(863)Program of China(grant numbers 2014AA020108,2012AA022-003)the National Natural Science Foundation of China(grant numbers 81273138,81572045)
文摘Dear Editor,The genus Orbivirus,within the family Reoviridae,includes 22 virus species(King et al.,2011).They are distributed globally,but are particularly prevalent in Europe,Asia,and Africa.In addition,they can be transmitted by ticks or other hematophagous insect vectors,including Culicoides,mosquitoes,and sandflies(Belaga-
基金supported by grants from the National Key R&D Program of China(2017YFC1200802)National Science and Technology Major Project of China(2018ZX10711001003-001)+1 种基金the State Key Laboratories Program of China(SKLPBS1817)the Yunnan Health Training Project of High Level Talents(D-201604)
文摘Dear Editor,The family Totiviridae contains non-enveloped,doublestranded RNA viruses with genomes of approximately 4.6–7 kbp in length.These totiviruses are classified into five genera:Totivirus,Victorivirus,Trichomonasvirus,Giardiavirus,and Leishmaniavirus(Nibert 2007).They are associated with latent infections of fungal or protozoan hosts(Li et al.2020).Recently,a few totiviruses have been identified and shown to have unexpected host distributions,including insects,plants.
基金support by the National Natural Science Foundation of China(No.82172093)Tianjin Science and Technology Program(21JCYBJC01060).
文摘Selective removal of ultra-high low-density lipoprotein(LDL)from the blood of hyperlipemia patients using hemoperfusion is considered an efficient method to prevent the deterioration of atherosclerotic cardiovascular disease.Based on the exceptional structure–function properties of multistimulus-responsive materials,we developed a magnetic photorenewable nanoadsorbent(Fe_(3)O_(4)@SiO_(2)@Azo-COOH)with outstanding selectivity and regenerative characteristics,featuring functionalized azobenzene as the ligand.The dual-stimulus response endowed Fe_(3)O_(4)@SiO_(2)@Azo-COOH with rapid separation and photoregenerative properties.The adsorbent demonstrated excellent removal efficiency of LDL with an adsorption capacity of 15.06 mg/g,and highly repetitive adsorption performance(≥5 cycles)under irradiation.Fe_(3)O_(4)@SiO_(2)@Azo-COOH also exhibited remarkable adsorption properties and selectivity in human serum,with adsorption capacities of 10.93,21.26 and 9.80 mg/g for LDL,total cholesterol and triglycerides and only 0.77 mg/g for high-density lipoprotein(HDL),resulting in a 93%selective adsorption difference(LDL/HDL).Complete green regeneration of the nanoadsorbent was achieved through a simple regeneration process,maintaining a recovery rate of 99.4%after five regeneration experiments.By combining dynamic perfusion experiment with micromagnetic microfluidics,the LDL content decreased by 16.6%.Due to its superior adsorption capacity and regenerative properties,the dual stimulus-responsive nanosorbent is considered a potential hemoperfusion adsorbent.
