The Cooling Storage Ring of the Heavy Ion Research Facility in Lanzhou(HIRFL-CSR)was constructed to study nuclear physics,atomic physics,interdisciplinary science,and related applications.The External Target Facility(...The Cooling Storage Ring of the Heavy Ion Research Facility in Lanzhou(HIRFL-CSR)was constructed to study nuclear physics,atomic physics,interdisciplinary science,and related applications.The External Target Facility(ETF)is located in the main ring of the HIRFL-CSR.The gamma detector of the ETF is built to measure emitted gamma rays with energies below 5 MeV in the center-of-mass frame and is planned to measure light fragments with energies up to 300 MeV.The readout electronics for the gamma detector were designed and commissioned.The readout electronics consist of thirty-two front-end cards,thirty-two readout control units(RCUs),one common readout unit,one synchronization&clock unit,and one sub-trigger unit.By using the real-time peak-detection algorithm implemented in the RCU,the data volume can be significantly reduced.In addition,trigger logic selection algorithms are implemented to improve the selection of useful events and reduce the data size.The test results show that the integral nonlinearity of the readout electronics is less than 1%,and the energy resolution for measuring the 60 Co source is better than 5.5%.This study discusses the design and performance of the readout electronics.展开更多
In this study, we hypothesized that an increase in integrin αβand its co-activator vascular endothelial growth factor play important neuroprotective roles in ischemic injury. We performed ischemic preconditioning wi...In this study, we hypothesized that an increase in integrin αβand its co-activator vascular endothelial growth factor play important neuroprotective roles in ischemic injury. We performed ischemic preconditioning with bilateral common carotid artery occlusion for 5 minutes in C57BL/6J mice. This was followed by ischemic injury with bilateral common carotid artery occlusion for 30 minutes. The time interval between ischemic preconditioning and lethal ischemia was 48 hours. Histopathological analysis showed that ischemic preconditioning substantially diminished damage to neurons in the hippocampus 7 days after ischemia. Evans Blue dye assay showed that ischemic preconditioning reduced damage to the blood-brain barrier 24 hours after ischemia. This demonstrates the neuroprotective effect of ischemic preconditioning. Western blot assay revealed a significant reduction in protein levels of integrin αβ, vascular endothelial growth factor and its receptor in mice given ischemic preconditioning compared with mice not given ischemic preconditioning 24 hours after ischemia. These findings suggest that the neuroprotective effect of ischemic preconditioning is associated with lower integrin αβand vascular endothelial growth factor levels in the brain following ischemia.展开更多
By using the three-dimensional classical ensemble model,the recollision dynamics in nonsequential double ionization(NSDI)of Ar by 780-nm laser pulses at(6-1.2)×10^(14)W/cm^(2) was extensively studied.We revealed ...By using the three-dimensional classical ensemble model,the recollision dynamics in nonsequential double ionization(NSDI)of Ar by 780-nm laser pulses at(6-1.2)×10^(14)W/cm^(2) was extensively studied.We revealed the picture of multiplerecollision in the double ionization events at the laser intensity region below the recollision-ionization threshold.Via tracing the NSDI trajectories,it was found that the contribution of these multiple-recollision events increases as the laser intensity decreases.In this low intensity region,many multiple-recollision induced NSDI trajectories occur through the doubly excited states.The decay speed of the doubly excited state decreases with the decreasing laser intensity.展开更多
基金supported by the National Natural Science Foundation of China (Nos. 12222512, 12375193, U2031206, U1831206, and U2032209)the Scientific Instrument Developing Project of the Chinese Academy of Sciences (GJJSTD20210009)+1 种基金the CAS Pioneer Hundred Talent Programthe CAS Light of West China Program
文摘The Cooling Storage Ring of the Heavy Ion Research Facility in Lanzhou(HIRFL-CSR)was constructed to study nuclear physics,atomic physics,interdisciplinary science,and related applications.The External Target Facility(ETF)is located in the main ring of the HIRFL-CSR.The gamma detector of the ETF is built to measure emitted gamma rays with energies below 5 MeV in the center-of-mass frame and is planned to measure light fragments with energies up to 300 MeV.The readout electronics for the gamma detector were designed and commissioned.The readout electronics consist of thirty-two front-end cards,thirty-two readout control units(RCUs),one common readout unit,one synchronization&clock unit,and one sub-trigger unit.By using the real-time peak-detection algorithm implemented in the RCU,the data volume can be significantly reduced.In addition,trigger logic selection algorithms are implemented to improve the selection of useful events and reduce the data size.The test results show that the integral nonlinearity of the readout electronics is less than 1%,and the energy resolution for measuring the 60 Co source is better than 5.5%.This study discusses the design and performance of the readout electronics.
基金supported by grants from the National Natural Science Foundation of China,No.81071068the Israel Science Foundation-the National Natural Science Foundation of China(Joint Program),No.813111290the Natural Science Foundation of Guangdong Province in China,No.2014A030313172
文摘In this study, we hypothesized that an increase in integrin αβand its co-activator vascular endothelial growth factor play important neuroprotective roles in ischemic injury. We performed ischemic preconditioning with bilateral common carotid artery occlusion for 5 minutes in C57BL/6J mice. This was followed by ischemic injury with bilateral common carotid artery occlusion for 30 minutes. The time interval between ischemic preconditioning and lethal ischemia was 48 hours. Histopathological analysis showed that ischemic preconditioning substantially diminished damage to neurons in the hippocampus 7 days after ischemia. Evans Blue dye assay showed that ischemic preconditioning reduced damage to the blood-brain barrier 24 hours after ischemia. This demonstrates the neuroprotective effect of ischemic preconditioning. Western blot assay revealed a significant reduction in protein levels of integrin αβ, vascular endothelial growth factor and its receptor in mice given ischemic preconditioning compared with mice not given ischemic preconditioning 24 hours after ischemia. These findings suggest that the neuroprotective effect of ischemic preconditioning is associated with lower integrin αβand vascular endothelial growth factor levels in the brain following ischemia.
基金Project supported by the Natural Science Foundation of Hubei Province,China(Grant No.2020CFB362)Scientific Research Program of Hubei Provincial Department of Education,China(Grant No.B2020176)the National Natural Science Foundation of China(Grant No.12104389)。
文摘By using the three-dimensional classical ensemble model,the recollision dynamics in nonsequential double ionization(NSDI)of Ar by 780-nm laser pulses at(6-1.2)×10^(14)W/cm^(2) was extensively studied.We revealed the picture of multiplerecollision in the double ionization events at the laser intensity region below the recollision-ionization threshold.Via tracing the NSDI trajectories,it was found that the contribution of these multiple-recollision events increases as the laser intensity decreases.In this low intensity region,many multiple-recollision induced NSDI trajectories occur through the doubly excited states.The decay speed of the doubly excited state decreases with the decreasing laser intensity.
