Hepatic encephalopathy(HE)is a complex,neuropsychiatric abnormality that occurs as a consequence of metabolic disorders in patients with hepatic insufficiency.The pathogenesis is complex with a strong prognosticator o...Hepatic encephalopathy(HE)is a complex,neuropsychiatric abnormality that occurs as a consequence of metabolic disorders in patients with hepatic insufficiency.The pathogenesis is complex with a strong prognosticator of death.To standardize the clinical management of HE,relevant new data were reviewed and assessed by Chinese Committee of Experts on Hepatic Encephalopathy in China and was discussed and debated extensively.Then the consensus on the management of HE was developed.The final recommendations are based on the data available at the time of production of the document and may be updated with pertinent scientific developments at a later time.All the discussion was organized by the editorial board of Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition),Chinese Journal of Liver Diseases(Electronic Edition)and Infection International(Electronic Edition).The evidence gradings in the consensus are listed in Table1.展开更多
A 50-year-old man with ankylosing spondylitis was treated successfully with infliximab,who was also a HBV carrier for about twenty-five years.After injection with infliximab for four times,he developed jaundice and HB...A 50-year-old man with ankylosing spondylitis was treated successfully with infliximab,who was also a HBV carrier for about twenty-five years.After injection with infliximab for four times,he developed jaundice and HBV DNA was detectable in serum.Serum aminotransferase and total bilirubin levels were higher than normal.Then he was hospitalized and treated with entacavir and Chinese herb medicine.But his liver damage aggravated and was diagnosed as acute on chronic liver failure.Finally,liver transplantation was carried out and he was cured successfully.展开更多
文摘Hepatic encephalopathy(HE)is a complex,neuropsychiatric abnormality that occurs as a consequence of metabolic disorders in patients with hepatic insufficiency.The pathogenesis is complex with a strong prognosticator of death.To standardize the clinical management of HE,relevant new data were reviewed and assessed by Chinese Committee of Experts on Hepatic Encephalopathy in China and was discussed and debated extensively.Then the consensus on the management of HE was developed.The final recommendations are based on the data available at the time of production of the document and may be updated with pertinent scientific developments at a later time.All the discussion was organized by the editorial board of Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition),Chinese Journal of Liver Diseases(Electronic Edition)and Infection International(Electronic Edition).The evidence gradings in the consensus are listed in Table1.
文摘A 50-year-old man with ankylosing spondylitis was treated successfully with infliximab,who was also a HBV carrier for about twenty-five years.After injection with infliximab for four times,he developed jaundice and HBV DNA was detectable in serum.Serum aminotransferase and total bilirubin levels were higher than normal.Then he was hospitalized and treated with entacavir and Chinese herb medicine.But his liver damage aggravated and was diagnosed as acute on chronic liver failure.Finally,liver transplantation was carried out and he was cured successfully.
