Insomnia is one of the most common clinical health problems,which can lead to a variety of complications and seriously affect human physical and mental health.Acupuncture has been used for treating insomnia for thousa...Insomnia is one of the most common clinical health problems,which can lead to a variety of complications and seriously affect human physical and mental health.Acupuncture has been used for treating insomnia for thousands of years,and is currently widely used as an alternative thehere is still a lack of up-to-date and comprehensive understanding of the mechanism of acupuncture for insorapy for insomnia all over the world.However,the mechanism of acupuncture for insomnia is still unclear,the mechanism research is relatively discrete,and tmnia.After summary and analysis in this study,it is found that acupuncture may improve sleeping by adjusting central neurotransmitter,insomnia-related hormone,circadian rhythm,sleep structure,and brain function.How to scientifically explain the scientific mechanism of acupuncture in treating insomnia has great challenges.I hope this study can provide reference for future research on the mechanism of acupuncture for insomnia.展开更多
Pyridine-bridged bis-benzimidazolylidene nickel complexes exhibited very high catalytic activity toward cross coupling of inactive(hetero)aryl benzylic ammonium salts with(hetero)aryl and alkenyl boronic acids und...Pyridine-bridged bis-benzimidazolylidene nickel complexes exhibited very high catalytic activity toward cross coupling of inactive(hetero)aryl benzylic ammonium salts with(hetero)aryl and alkenyl boronic acids under mild reaction conditions.Even at 2 mol% catalyst loading,a wide range of substrates for both coupling partners with different steric and electronic properties were well tolerated.展开更多
基金National Administration of Traditional Chinese Medicine(No.ZZ-06)。
文摘Insomnia is one of the most common clinical health problems,which can lead to a variety of complications and seriously affect human physical and mental health.Acupuncture has been used for treating insomnia for thousands of years,and is currently widely used as an alternative thehere is still a lack of up-to-date and comprehensive understanding of the mechanism of acupuncture for insorapy for insomnia all over the world.However,the mechanism of acupuncture for insomnia is still unclear,the mechanism research is relatively discrete,and tmnia.After summary and analysis in this study,it is found that acupuncture may improve sleeping by adjusting central neurotransmitter,insomnia-related hormone,circadian rhythm,sleep structure,and brain function.How to scientifically explain the scientific mechanism of acupuncture in treating insomnia has great challenges.I hope this study can provide reference for future research on the mechanism of acupuncture for insomnia.
基金the National Natural Science Foundation of China (Nos. 21572036, 21172045 and 91127041)the Changjiang Scholars and Innovative Research Team in University (No. IRT-15R12)+2 种基金the Shanghai International Cooperation Program (No. 14230710600)the Doctoral Fund of Ministry of Education of China (No. 20130071110032)Department of Chemistry Hehai University
文摘Pyridine-bridged bis-benzimidazolylidene nickel complexes exhibited very high catalytic activity toward cross coupling of inactive(hetero)aryl benzylic ammonium salts with(hetero)aryl and alkenyl boronic acids under mild reaction conditions.Even at 2 mol% catalyst loading,a wide range of substrates for both coupling partners with different steric and electronic properties were well tolerated.