A taxonomic study of the genus Antitrygodes Warren, 1895 in China was conducted. Two species, Antitrygodes vicina(Thierry-Mieg) and Antitrygodes cuneilinea(Walker), are reported for the first time from China. Descript...A taxonomic study of the genus Antitrygodes Warren, 1895 in China was conducted. Two species, Antitrygodes vicina(Thierry-Mieg) and Antitrygodes cuneilinea(Walker), are reported for the first time from China. Description and diagnoses for these species are provided and illustrations of adults and genitalia are presented. The species list for this genus of the world is also provided.展开更多
Since its establishment in 2013,BioLiP has become one of the widely used resources for protein-ligand interactions.Nevertheless,several known issues occurred with it over the past decade.For example,the protein-ligand...Since its establishment in 2013,BioLiP has become one of the widely used resources for protein-ligand interactions.Nevertheless,several known issues occurred with it over the past decade.For example,the protein-ligand interactions are represented in the form of single chain-based tertiary structures,which may be inappropriate as many interactions involve multiple protein chains(known as quaternary structures).We sought to address these issues,resulting in Q-BioLiP,a comprehensive resource for quaternary structure-based protein-ligand interactions.The major features of Q-BioLiP include:(1)representing protein structures in the form of quaternary structures rather than single chain-based tertiary structures;(2)pairing DNA/RNA chains properly rather than separation;(3)providing both experimental and predicted binding affinities;(4)retaining both biologically relevant and irrelevant interactions to alleviate the wrong justification of ligands’biological relevance;and(5)developing a new quaternary structure-based algorithm for the modelling of protein-ligand complex structure.With these new features,Q-BioLiP is expected to be a valuable resource for studying biomolecule interactions,including protein-small molecule interaction,protein-metal ion interaction,protein-peptide interaction,protein-protein interaction,protein-DNA/RNA interaction,and RNA-small molecule interaction.Q-BioLiP is freely available at https://yanglab.qd.sdu.edu.cn/Q-BioLiP/.展开更多
Based on the demand of carbon peak and carbon emission reduction strategy, divinyl-terminated polydimethyl-siloxane (ViPDMSVi), poly(methylhydrosiloxane) (PMHS), divinyl-terminated polymethylvinylsiloxane (ViPMVSVi), ...Based on the demand of carbon peak and carbon emission reduction strategy, divinyl-terminated polydimethyl-siloxane (ViPDMSVi), poly(methylhydrosiloxane) (PMHS), divinyl-terminated polymethylvinylsiloxane (ViPMVSVi), and fumed silica were used as primary raw materials, polydimethylsiloxane (PDMS) synthetic leather coating was in situ constructed by thermally induced hydrosilylation polymerization on the synthetic leather substrate. The effect of the viscosity of ViPDMSVi, the active hydrogen content of PMHS, the molar ratio of vinyl groups to active hydrogen, the dosage of ViPMVSVi and fumed silica on the performance of PDMS polymer coating, including mechanical properties, cold resistance, flexural resistance, abrasion resistance, hydrophobic and anti-fouling properties were investigated. The results show that ViPDMSVi with high vinyl content and PMHS with low active hydrogen content is more conducive to obtaining organosilicon coating with better mechanical properties, the optimized dosage of ViPMVSVi and fumed silica was 7 wt% and 40 wt%, respectively. In this case, the tensile strength and the broken elongation of the PDMS polymer coating reached 5.96 MPa and 481%, showing reasonable mechanical properties for leather coating. Compared with polyurethane based or polyvinyl chloride based synthetic leather, the silicon based synthetic leather prepared by this method exhibits excellent cold resistance, abrasion resistance, super hydrophobicity, and anti-fouling characteristics.展开更多
Except for fluorocarbons and silicones,few artificial materials display both water and organic solvent resistance.Herein,we report an artificial hydrocarbonbased supramolecular elastomer that displays unprecedented du...Except for fluorocarbons and silicones,few artificial materials display both water and organic solvent resistance.Herein,we report an artificial hydrocarbonbased supramolecular elastomer that displays unprecedented dual resistance to both water and organic solvents.This elastomer is formed in water with two water soluble components,folic acid(FA)and branched poly(ethylene imine)(b-PEI).The hydrogen bonding between the two components occurs immediately,which further promotes the hydrogen bonding between the FA,yielding folate quartets and theirπ-πstacking.These multiple noncovalent interactions work synergistically,leading to a hydrophobic,transparent,stretchable,healable,notchinsensitive,and recyclable elastomer that resists both water and organic solvents.The elastomer remains intact after storage in high humidity and organic solvents for months.Films generated by stretching the elastomer are very hydrophobic,and the contact angle of water on the elastomer is up to 112.3°.The damaged elastomers also exhibit water-assisted healable behavior.This work discloses a new paradigm of material synthesis that can inspire the fabrication of robust nonfluorocarbon and silicone-based materials with green strategies.展开更多
This study systematically investigated the influence of the microstructure evolution,mechanical properties and corrosion behaviors on Zn–1.5Mg(wt%)alloy processed by room-temperature rolling.The as-cast Zn–1.5Mg all...This study systematically investigated the influence of the microstructure evolution,mechanical properties and corrosion behaviors on Zn–1.5Mg(wt%)alloy processed by room-temperature rolling.The as-cast Zn–1.5Mg alloy consists ofη-Zn matrix andη-Zn+Mg_(2)Zn_(11)eutectic structure.As rolling reduction increases,the average grain size of the alloy reduces from 42.9 to 1.7μm,and the eutectic structure undergoes fragmentation and refinement,changing from a network distribution surrounding the matrix to a lamellar alternating distribution with the matrix.The ultimate tensile strength of the as-rolled alloy(80%reduction)is increased to 366±3.7 MPa,along with a good elongation of 18.4%±2.0%.Immersion tests in Hanks’solution indicate that the initial corrosion rate of the 80%-rolled alloy is 0.030 mm/year and finally stabilizes at 0.034 mm/year when the immersion duration is extended to 21 days.According to X-ray diffractometer and X-ray photoelectron spectroscopy analyses,Ca_(3)(PO_(4))_(2),CaCO_(3),Ca(OH)_(2),Zn_(3)(PO_(4))_(2),Zn(OH)_(2),ZnO and a small amount of MgO and MgCO_(3)are the main corrosion products on the surface.Due to the microstructure refinement,the developed alloy exhibits uniform corrosion,and the corrosion morphology is dominated by pitting pits.展开更多
Based on the demand of carbon peak and carbon emission reduction strategy,divinyl-terminated polydimethyl-siloxane(^(Vi)PDMS^(Vi)),poly(methylhydrosiloxane)(PMHS),divinyl-terminated polymethylvinylsiloxane(ViPMVSVi),a...Based on the demand of carbon peak and carbon emission reduction strategy,divinyl-terminated polydimethyl-siloxane(^(Vi)PDMS^(Vi)),poly(methylhydrosiloxane)(PMHS),divinyl-terminated polymethylvinylsiloxane(ViPMVSVi),and fumed silica were used as primary raw materials,polydimethylsiloxane(PDMS)synthetic leather coating was in situ constructed by thermally induced hydrosilylation polymerization on the synthetic leather substrate.The effect of the viscosity of^(Vi)PDMS^(Vi),the active hydrogen content of PMHS,the molar ratio of vinyl groups to active hydrogen,the dosage of ViPMVSVi and fumed silica on the performance of PDMS polymer coating,including mechanical properties,cold resistance,flexural resistance,abrasion resistance,hydrophobic and anti-fouling properties were investigated.The results show that^(Vi)PDMS^(Vi)with high vinyl content and PMHS with low active hydrogen content is more conducive to obtaining organosilicon coating with better mechanical properties,the optimized dosage of ViPMVSVi and fumed silica was 7 wt%and 40 wt%,respectively.In this case,the tensile strength and the broken elongation of the PDMS polymer coating reached 5.96 MPa and 481%,showing reasonable mechanical properties for leather coating.Compared with polyurethane based or polyvinyl chloride based synthetic leather,the silicon based synthetic leather prepared by this method exhibits excellent cold resistance,abrasion resistance,super hydrophobicity,and anti-fouling characteristics.展开更多
General strategies leading to scale-span molecular self-assembly are of crucial importance in creating bulk supramolecular materials.Here,we report that under mechanical pressure,caking of the precipitatedmolecular se...General strategies leading to scale-span molecular self-assembly are of crucial importance in creating bulk supramolecular materials.Here,we report that under mechanical pressure,caking of the precipitatedmolecular self-assemblies led to bulk supramolecular films.Massive fabrication of supramolecular films became possible by employing a simple household noodle machine.The film could be endowed to acquire diversified functions by depositing various functional ingredients via coprecipitation.We expect that our current work opens up a new paradigm leading to large-scale functional solid molecular self-assembled materials.展开更多
Human skin moisture is closely related to health and personal care issues.Many creams were developed to claim capable of skin moisturizing.However,people can hardly check their skin moisture status and the moisturizin...Human skin moisture is closely related to health and personal care issues.Many creams were developed to claim capable of skin moisturizing.However,people can hardly check their skin moisture status and the moisturizing effect of various creams conveniently,since currently all the skin moisturizing detection rely on large equipment requiring power supply.Herein,we report a power-supply independent supramolecular film that is able to directly report the moisturizing status of the skin.With the strategy of solid-phase molecular self-assembly(SPMSA),the aqueous precipitates formed by commercially available polyelectrolyte and oppositely charged surfactant would transform into a supramolecular film under a mild mechanical pressure,where the hydrophobic surfactant domains bridged by polyelectrolyte merge into hydrophobic mesophases to reduce interfacial energy.The hydrophobic mesophase will greatly retard water diffusion inside the film,so that a humidity gradient is generated as the film is exposed to a humid environment.The film will bend upward automatically in touch with moisture skin,and the bending degree is proportional to the skin moisture status.Therefore,the film can be used as portable smart power-free skin moisture sensor.展开更多
Background Accurate measurement of left ventricular ejection fraction(LVEF)is crucial in diagnosing and managing cardiac conditions.Deep learning(DL)models offer potential to improve the consistency and efficiency of ...Background Accurate measurement of left ventricular ejection fraction(LVEF)is crucial in diagnosing and managing cardiac conditions.Deep learning(DL)models offer potential to improve the consistency and efficiency of these measurements,reducing reliance on operator expertise.Objective The aim of this study was to develop an innovative software-hardware combined device,featuring a novel DL algorithm for the automated quantification of LVEF from 2D echocardiographic images.Methods A dataset of 2,113 patients admitted to the Affiliated Hospital of Qingdao University between January and June 2023 was assembled and split into training and test groups.Another 500 patients from another campus were prospectively collected as external validation group.The age,sex,reason for echocardiography and the type of patients were collected.Following standardized protocol training by senior echocardiographers using domestic ultrasound equipment,apical four-chamber view images were labeled manually and utilized for training our deep learning framework.This system combined convolutional neural networks(CNN)with transformers for enhanced image recognition and analysis.Combined with the model that was named QHAutoEF,a‘one-touch’software module was developed and integrated into the echocardiography hardware,providing intuitive,realtime visualization of LVEF measurements.The device’s performance was evaluated with metrics such as the Dice coefficient and Jaccard index,along with computational efficiency indicators.The dice index,intersection over union,size,floating point operations per second and calculation time were used to compare the performance of our model with alternative deep learning architectures.Bland-Altman analysis and the receiver operating characteristic(ROC)curve were used for validation of the accuracy of the model.The scatter plot was used to evaluate the consistency of the manual and automated results among subgroups.Results Patients from external validation group were older than those from training group((60±14)years vs.(55±16)years,respectively,P<0.001).The gender distribution among three groups were showed no statistical difference(43%vs.42%vs.50%,respectively,P=0.095).Significant differences were showed among patients with different type(all P<0.001)and reason for echocardiography(all P<0.001 except for other reasons).QHAutoEF achieved a high Dice index(0.942 at end-diastole,0.917 at end-systole)with a notably compact model size(10.2 MB)and low computational cost(93.86 G floating point operations(FLOPs)).It exhibited high consistency with expert manual measurements(intraclass correlation coefficient(ICC)=0.90(0.89,0.92),P<0.001)and excellent capability to differentiate patients with LVEF≥60%from those with reduced function,yielding an area under the operation curve(AUC)of 0.92(0.90–0.95).Subgroup analysis showed a good correlation between QHAutoEF results and manual results from experienced experts among patients of different types(R=0.93,0.73,0.92,respectively,P<0.001)and ages(R=0.92,0.94,0.89,0.91,0.81,respectively,P<0.001).Conclusions Our software-hardware device offers an improved solution for the automated measurement of LVEF,demonstrating not only high accuracy and consistency with manual expert measurements but also practical adaptability for clinical settings.This device might potentially support clinicians and augment clinical decision.展开更多
基金We express our sincere thanks to Prof.Dayong XUE for his help on the identification of the species and to Chao YANG for dissecting the specimensThis project was supported by the National Natural Science Foundation of China(31872967,31672331)the Ministry of Science and Technology of China(2015FY210300).
文摘A taxonomic study of the genus Antitrygodes Warren, 1895 in China was conducted. Two species, Antitrygodes vicina(Thierry-Mieg) and Antitrygodes cuneilinea(Walker), are reported for the first time from China. Description and diagnoses for these species are provided and illustrations of adults and genitalia are presented. The species list for this genus of the world is also provided.
基金supported in part by the National Natural Science Foundation of China(Grant Nos.T2225007 and T2222012)the Foundation for Innovative Research Groups of State Key Laboratory of Microbial Technology,China(Grant No.WZCX2021-03).
文摘Since its establishment in 2013,BioLiP has become one of the widely used resources for protein-ligand interactions.Nevertheless,several known issues occurred with it over the past decade.For example,the protein-ligand interactions are represented in the form of single chain-based tertiary structures,which may be inappropriate as many interactions involve multiple protein chains(known as quaternary structures).We sought to address these issues,resulting in Q-BioLiP,a comprehensive resource for quaternary structure-based protein-ligand interactions.The major features of Q-BioLiP include:(1)representing protein structures in the form of quaternary structures rather than single chain-based tertiary structures;(2)pairing DNA/RNA chains properly rather than separation;(3)providing both experimental and predicted binding affinities;(4)retaining both biologically relevant and irrelevant interactions to alleviate the wrong justification of ligands’biological relevance;and(5)developing a new quaternary structure-based algorithm for the modelling of protein-ligand complex structure.With these new features,Q-BioLiP is expected to be a valuable resource for studying biomolecule interactions,including protein-small molecule interaction,protein-metal ion interaction,protein-peptide interaction,protein-protein interaction,protein-DNA/RNA interaction,and RNA-small molecule interaction.Q-BioLiP is freely available at https://yanglab.qd.sdu.edu.cn/Q-BioLiP/.
基金the National Natural Science Foundation of China(Project No.22178238)the Pioneers&Leader Research and Development Program of Zhejiang Province(Project No.2022C01190).
文摘Based on the demand of carbon peak and carbon emission reduction strategy, divinyl-terminated polydimethyl-siloxane (ViPDMSVi), poly(methylhydrosiloxane) (PMHS), divinyl-terminated polymethylvinylsiloxane (ViPMVSVi), and fumed silica were used as primary raw materials, polydimethylsiloxane (PDMS) synthetic leather coating was in situ constructed by thermally induced hydrosilylation polymerization on the synthetic leather substrate. The effect of the viscosity of ViPDMSVi, the active hydrogen content of PMHS, the molar ratio of vinyl groups to active hydrogen, the dosage of ViPMVSVi and fumed silica on the performance of PDMS polymer coating, including mechanical properties, cold resistance, flexural resistance, abrasion resistance, hydrophobic and anti-fouling properties were investigated. The results show that ViPDMSVi with high vinyl content and PMHS with low active hydrogen content is more conducive to obtaining organosilicon coating with better mechanical properties, the optimized dosage of ViPMVSVi and fumed silica was 7 wt% and 40 wt%, respectively. In this case, the tensile strength and the broken elongation of the PDMS polymer coating reached 5.96 MPa and 481%, showing reasonable mechanical properties for leather coating. Compared with polyurethane based or polyvinyl chloride based synthetic leather, the silicon based synthetic leather prepared by this method exhibits excellent cold resistance, abrasion resistance, super hydrophobicity, and anti-fouling characteristics.
基金This work was financially supported by the National Natural Science Foundation of China(grant nos.NSFC 22172004 and 21972003)and the Beijing National Laboratory for Molecular Sciences(BNLMS)for financial support.
文摘Except for fluorocarbons and silicones,few artificial materials display both water and organic solvent resistance.Herein,we report an artificial hydrocarbonbased supramolecular elastomer that displays unprecedented dual resistance to both water and organic solvents.This elastomer is formed in water with two water soluble components,folic acid(FA)and branched poly(ethylene imine)(b-PEI).The hydrogen bonding between the two components occurs immediately,which further promotes the hydrogen bonding between the FA,yielding folate quartets and theirπ-πstacking.These multiple noncovalent interactions work synergistically,leading to a hydrophobic,transparent,stretchable,healable,notchinsensitive,and recyclable elastomer that resists both water and organic solvents.The elastomer remains intact after storage in high humidity and organic solvents for months.Films generated by stretching the elastomer are very hydrophobic,and the contact angle of water on the elastomer is up to 112.3°.The damaged elastomers also exhibit water-assisted healable behavior.This work discloses a new paradigm of material synthesis that can inspire the fabrication of robust nonfluorocarbon and silicone-based materials with green strategies.
基金the Key Research and Development Program of Jiangsu Province(BE2021027)the Project on Excellent Postgraduate Dissertation of Hohai University(422003518)+2 种基金the Postgraduate Research&Practice Innovation Program of Jiangsu Province(SJCX23_0175)the Opening Project of Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology(ASMA202102)the Jiangsu Key Laboratory for Light Metal Alloys(LMA202101).
文摘This study systematically investigated the influence of the microstructure evolution,mechanical properties and corrosion behaviors on Zn–1.5Mg(wt%)alloy processed by room-temperature rolling.The as-cast Zn–1.5Mg alloy consists ofη-Zn matrix andη-Zn+Mg_(2)Zn_(11)eutectic structure.As rolling reduction increases,the average grain size of the alloy reduces from 42.9 to 1.7μm,and the eutectic structure undergoes fragmentation and refinement,changing from a network distribution surrounding the matrix to a lamellar alternating distribution with the matrix.The ultimate tensile strength of the as-rolled alloy(80%reduction)is increased to 366±3.7 MPa,along with a good elongation of 18.4%±2.0%.Immersion tests in Hanks’solution indicate that the initial corrosion rate of the 80%-rolled alloy is 0.030 mm/year and finally stabilizes at 0.034 mm/year when the immersion duration is extended to 21 days.According to X-ray diffractometer and X-ray photoelectron spectroscopy analyses,Ca_(3)(PO_(4))_(2),CaCO_(3),Ca(OH)_(2),Zn_(3)(PO_(4))_(2),Zn(OH)_(2),ZnO and a small amount of MgO and MgCO_(3)are the main corrosion products on the surface.Due to the microstructure refinement,the developed alloy exhibits uniform corrosion,and the corrosion morphology is dominated by pitting pits.
基金support from the National Natural Science Foundation of China(Project No.22178238)the Pioneers&Leader Research and Development Program of Zhejiang Province(Project No.2022C01190).
文摘Based on the demand of carbon peak and carbon emission reduction strategy,divinyl-terminated polydimethyl-siloxane(^(Vi)PDMS^(Vi)),poly(methylhydrosiloxane)(PMHS),divinyl-terminated polymethylvinylsiloxane(ViPMVSVi),and fumed silica were used as primary raw materials,polydimethylsiloxane(PDMS)synthetic leather coating was in situ constructed by thermally induced hydrosilylation polymerization on the synthetic leather substrate.The effect of the viscosity of^(Vi)PDMS^(Vi),the active hydrogen content of PMHS,the molar ratio of vinyl groups to active hydrogen,the dosage of ViPMVSVi and fumed silica on the performance of PDMS polymer coating,including mechanical properties,cold resistance,flexural resistance,abrasion resistance,hydrophobic and anti-fouling properties were investigated.The results show that^(Vi)PDMS^(Vi)with high vinyl content and PMHS with low active hydrogen content is more conducive to obtaining organosilicon coating with better mechanical properties,the optimized dosage of ViPMVSVi and fumed silica was 7 wt%and 40 wt%,respectively.In this case,the tensile strength and the broken elongation of the PDMS polymer coating reached 5.96 MPa and 481%,showing reasonable mechanical properties for leather coating.Compared with polyurethane based or polyvinyl chloride based synthetic leather,the silicon based synthetic leather prepared by this method exhibits excellent cold resistance,abrasion resistance,super hydrophobicity,and anti-fouling characteristics.
基金the National Natural Science Foundation of China(NSFC 91856120,21573011,and 21633002).
文摘General strategies leading to scale-span molecular self-assembly are of crucial importance in creating bulk supramolecular materials.Here,we report that under mechanical pressure,caking of the precipitatedmolecular self-assemblies led to bulk supramolecular films.Massive fabrication of supramolecular films became possible by employing a simple household noodle machine.The film could be endowed to acquire diversified functions by depositing various functional ingredients via coprecipitation.We expect that our current work opens up a new paradigm leading to large-scale functional solid molecular self-assembled materials.
基金National Natural Science Foundation of China,Grant/Award Numbers:22172004,91856120,21972003。
文摘Human skin moisture is closely related to health and personal care issues.Many creams were developed to claim capable of skin moisturizing.However,people can hardly check their skin moisture status and the moisturizing effect of various creams conveniently,since currently all the skin moisturizing detection rely on large equipment requiring power supply.Herein,we report a power-supply independent supramolecular film that is able to directly report the moisturizing status of the skin.With the strategy of solid-phase molecular self-assembly(SPMSA),the aqueous precipitates formed by commercially available polyelectrolyte and oppositely charged surfactant would transform into a supramolecular film under a mild mechanical pressure,where the hydrophobic surfactant domains bridged by polyelectrolyte merge into hydrophobic mesophases to reduce interfacial energy.The hydrophobic mesophase will greatly retard water diffusion inside the film,so that a humidity gradient is generated as the film is exposed to a humid environment.The film will bend upward automatically in touch with moisture skin,and the bending degree is proportional to the skin moisture status.Therefore,the film can be used as portable smart power-free skin moisture sensor.
文摘Background Accurate measurement of left ventricular ejection fraction(LVEF)is crucial in diagnosing and managing cardiac conditions.Deep learning(DL)models offer potential to improve the consistency and efficiency of these measurements,reducing reliance on operator expertise.Objective The aim of this study was to develop an innovative software-hardware combined device,featuring a novel DL algorithm for the automated quantification of LVEF from 2D echocardiographic images.Methods A dataset of 2,113 patients admitted to the Affiliated Hospital of Qingdao University between January and June 2023 was assembled and split into training and test groups.Another 500 patients from another campus were prospectively collected as external validation group.The age,sex,reason for echocardiography and the type of patients were collected.Following standardized protocol training by senior echocardiographers using domestic ultrasound equipment,apical four-chamber view images were labeled manually and utilized for training our deep learning framework.This system combined convolutional neural networks(CNN)with transformers for enhanced image recognition and analysis.Combined with the model that was named QHAutoEF,a‘one-touch’software module was developed and integrated into the echocardiography hardware,providing intuitive,realtime visualization of LVEF measurements.The device’s performance was evaluated with metrics such as the Dice coefficient and Jaccard index,along with computational efficiency indicators.The dice index,intersection over union,size,floating point operations per second and calculation time were used to compare the performance of our model with alternative deep learning architectures.Bland-Altman analysis and the receiver operating characteristic(ROC)curve were used for validation of the accuracy of the model.The scatter plot was used to evaluate the consistency of the manual and automated results among subgroups.Results Patients from external validation group were older than those from training group((60±14)years vs.(55±16)years,respectively,P<0.001).The gender distribution among three groups were showed no statistical difference(43%vs.42%vs.50%,respectively,P=0.095).Significant differences were showed among patients with different type(all P<0.001)and reason for echocardiography(all P<0.001 except for other reasons).QHAutoEF achieved a high Dice index(0.942 at end-diastole,0.917 at end-systole)with a notably compact model size(10.2 MB)and low computational cost(93.86 G floating point operations(FLOPs)).It exhibited high consistency with expert manual measurements(intraclass correlation coefficient(ICC)=0.90(0.89,0.92),P<0.001)and excellent capability to differentiate patients with LVEF≥60%from those with reduced function,yielding an area under the operation curve(AUC)of 0.92(0.90–0.95).Subgroup analysis showed a good correlation between QHAutoEF results and manual results from experienced experts among patients of different types(R=0.93,0.73,0.92,respectively,P<0.001)and ages(R=0.92,0.94,0.89,0.91,0.81,respectively,P<0.001).Conclusions Our software-hardware device offers an improved solution for the automated measurement of LVEF,demonstrating not only high accuracy and consistency with manual expert measurements but also practical adaptability for clinical settings.This device might potentially support clinicians and augment clinical decision.
