Objective:To investigate the hypolipidaemic and antioxidant effects of aqueous leaf extract of Enicoslemma littorale(E.littorale)Blume(Ens)against ethanol induced hepatic injury in albino rats.Methods:Male albino rats...Objective:To investigate the hypolipidaemic and antioxidant effects of aqueous leaf extract of Enicoslemma littorale(E.littorale)Blume(Ens)against ethanol induced hepatic injury in albino rats.Methods:Male albino rats of six numbers in each group were undertaken for study.Hypolipidaemic and antioxidant effect of E.littorale Blume(Ens)aqueous leaf extract at a dosage of 250 mg/kg bw was evaluated.Results:Levels of serum and tissue cholesterol,triglycerides and free fatty acids were elevated and levels of tissue thiobarbituric acid reactive substances(TBARS)and lipid hydroperoxide were increased in ethanol treated rats.The activity levels of liver antioxidant enzymes such as superoxide dismutase(SOD),catalase(CAT),glutathione peroxidase(GPX)and glutathione-s-transferase(GST)were decreased.After adiminstration of extract of E,littorale Blume,levels of cholesterol,triglycerides and free fatty acids were decreased in serum and liver tissue,levels of TBARS and lipid hydroperoxide were decreased,and Ever antioxidant enzymes were increased in liver tissue;Conclusions:It can be concluded that the aqueous leaf extract of E,littorale Blume(Ens)has potent restorative effect on hyperlipidaemic and oxidative stress.展开更多
Objective:To evaluate the effect of aqueous seed extract of Solarium suratlense(S.suraltense)on the oxidative potential of cauda cpididymal spermatozoa.Methods:S.surattense seed extract was orally administered at the ...Objective:To evaluate the effect of aqueous seed extract of Solarium suratlense(S.suraltense)on the oxidative potential of cauda cpididymal spermatozoa.Methods:S.surattense seed extract was orally administered at the dosage of 10 mg/kg b.w.for 15 days,after which aspartate transferase(AST),alanine transferase(ALT),glutamate dehydrogenase(GDH),citric acid and isocitrate dehydrogenase(ICDH)were assayed.Results:The activity levels of the enzymes AST and ALT,which are considered to be the androgenicity in the sperm suspension,were depleted in the extract fed rats.The activity level of the enzyme ICDH,was reduced significantly in the treated group(P<0.00l).Conclusions:It can be concluded that the oral administration of the aqueous seed extract of S.surattense can deplete the oxidative stress of cauda epididymal spermatozoa in albino rats.展开更多
文摘Objective:To investigate the hypolipidaemic and antioxidant effects of aqueous leaf extract of Enicoslemma littorale(E.littorale)Blume(Ens)against ethanol induced hepatic injury in albino rats.Methods:Male albino rats of six numbers in each group were undertaken for study.Hypolipidaemic and antioxidant effect of E.littorale Blume(Ens)aqueous leaf extract at a dosage of 250 mg/kg bw was evaluated.Results:Levels of serum and tissue cholesterol,triglycerides and free fatty acids were elevated and levels of tissue thiobarbituric acid reactive substances(TBARS)and lipid hydroperoxide were increased in ethanol treated rats.The activity levels of liver antioxidant enzymes such as superoxide dismutase(SOD),catalase(CAT),glutathione peroxidase(GPX)and glutathione-s-transferase(GST)were decreased.After adiminstration of extract of E,littorale Blume,levels of cholesterol,triglycerides and free fatty acids were decreased in serum and liver tissue,levels of TBARS and lipid hydroperoxide were decreased,and Ever antioxidant enzymes were increased in liver tissue;Conclusions:It can be concluded that the aqueous leaf extract of E,littorale Blume(Ens)has potent restorative effect on hyperlipidaemic and oxidative stress.
基金Supported by postgraduate Department of Zoology,Voorhees College
文摘Objective:To evaluate the effect of aqueous seed extract of Solarium suratlense(S.suraltense)on the oxidative potential of cauda cpididymal spermatozoa.Methods:S.surattense seed extract was orally administered at the dosage of 10 mg/kg b.w.for 15 days,after which aspartate transferase(AST),alanine transferase(ALT),glutamate dehydrogenase(GDH),citric acid and isocitrate dehydrogenase(ICDH)were assayed.Results:The activity levels of the enzymes AST and ALT,which are considered to be the androgenicity in the sperm suspension,were depleted in the extract fed rats.The activity level of the enzyme ICDH,was reduced significantly in the treated group(P<0.00l).Conclusions:It can be concluded that the oral administration of the aqueous seed extract of S.surattense can deplete the oxidative stress of cauda epididymal spermatozoa in albino rats.
