Various acupuncture clinical trials have been conducted on migraine;however,the conclusions remain controversial especially when acupuncture was compared with sham acupuncture.Sham acupuncture is sometimes performed a...Various acupuncture clinical trials have been conducted on migraine;however,the conclusions remain controversial especially when acupuncture was compared with sham acupuncture.Sham acupuncture is sometimes performed at the same acupuncture points used for verum acupuncture despite the evidence on acupuncture point specificity.Four databases were searched for sham acupuncture or waiting list-controlled acupuncture trials for migraine on December 25,2023.Sham acupuncture was classified according to the needling points:sham acupuncture therapy at verum points(SATV)or at sham points(SATS).Network meta-analysis was performed based on the frequentist framework for headache pain intensity and response rate.A total of 18 studies involving 1936 participants were analyzed.Headache pain intensity and response rate were significantly improved in verum acupuncture compared with SATS.However,there was no significant difference between SATV and verum acupuncture.When comparing SATS and SATV,there was no significant difference in headache pain intensity and response rate;however,the results were in favor of SATV.The effect of the risk of bias on the certainty of evidence between verum and sham acupunctures was judged to be generally low.SATV should not be misused as a placebo control to evaluate the efficacy of acupuncture.展开更多
Research into the diagnostic methods and patterns of traditional East Asian medical （TEAM） systems of practice such as acupuncture and herbal medicine face certain challenges due to the nature of thinking in TEAM an...Research into the diagnostic methods and patterns of traditional East Asian medical （TEAM） systems of practice such as acupuncture and herbal medicine face certain challenges due to the nature of thinking in TEAM and the subjective basis of judgments made in practice. The TEAM-based diagnosis can take into account various findings and signs such as the appearance of the tongue, palpable qualities of the radial pulses, palpable qualities and findings on the abdomen, the complexion of the patient and so on. Both diagnostic findings and the patterns of diagnosis cannot be assumed to have objective bases or to be causally related to the complaints of the patient. However, the diagnoses of TEAM based acupuncture and herbal medicine have tended to look at pictures of the whole patient and rather than focus on a particular symptom, they have looked across a myriad of signs and symptoms to decide or identify the ＇pattern＇ of diagnosis according to the theory in question. Although open for selective and subjective biases each diagnosis pattern always comes with a prescribed treatment tailored to the pattern. Further, the same research requirements needed for the validation of the diagnoses are needed also for these clinical observations and judgments. Hence, it is necessary, albeit challenging for research on TEAM diagnoses to first address these issues before proceeding to more complex investigations such as the development of instruments for making diagnostic observations, instruments for forming diagnostic conclusions or studies investigating the physiological bases of the diagnostic patterns. Preliminary work has started and instruments have been made, but we suggest that any instrumentation must necessarily be first validated by matching of the calibrated or scaled observations or judgments to observations made and agreed upon by relevant experts. Reliability of all observations and judgments are needed before any other tool, technology or more advanced approach can proceed and also whenever the natural system of diagnosis-treatment is applied in clinical trials. In this paper the authors highlight the core problems and describe a step wise process for addressing them.展开更多
Objective： To explore the correlation between single acupoints used and the recurrence rate of cystitis among cystitis-prone women receiving acupuncture as a prophylactic treatment. Methods： In all, 58 cystitis-pron...Objective： To explore the correlation between single acupoints used and the recurrence rate of cystitis among cystitis-prone women receiving acupuncture as a prophylactic treatment. Methods： In all, 58 cystitis-prone women were included in the analysis. Customised acupuncture treatments were given twice a week, over 4 weeks. The main effect parameter was the number of cystitis episodes during the 6-month observation time. Residual urine was measured at baseline, 2, 4 and 6 months using portable ultrasound equipment. Sympathetic and vagotone nerve activities were measured by using skin conductance and respiratory sinus arrhythmia, respectively. Results： The main acupoints used for patients with Kidney （Shen） qi/yang deficiency were Shenshu （BL23）, Taixi （KI3）, Zhongji （CV3）, Sanyinjiao （SP6） and Pangguangshu （BL2.8）, compared with Taichong （LR3）, CV3, BL28, Yinlingquan （SP9） and SP6 for Liver （Gan） qi stagnation, and SP6, CV3, BL28, Zusanli （ST36） and SP9 for Spleen （Pi） qi/yang deficiency patients. The combination BL23 and KI3 were used in 16 women, 13 of which were Kidney pattern related patients. When used, the number of symptomatic episodes were reduced to a third compared with what occurred in the 42 women where this combination was not used （3/16 vs. 28/42, P〈0.05）. BL23 application correlated to a significant reduction in residual urine measured a few days after treatment. Patients with the pattern of Spleen qi/yang deficiency had an initial increase in residual urine after treatments. Conclusion： Treating Kidney pattern related patients with the combination of BL23 and KI3 resulted in far better outcome than other points/combination of points for other Chinese medicine diagnoses. The acupoint SP6 may be less indicated than previously assumed when treating cvstitis-Drone women DroDhvlacticalIv.展开更多
This article is based on two presentations held at Chinese medicine conference in Rothenburg （2013）, Germany and at the 19th Anniversary of Korean Institute of Oriental Medicine （KIOM） International Symposium of C...This article is based on two presentations held at Chinese medicine conference in Rothenburg （2013）, Germany and at the 19th Anniversary of Korean Institute of Oriental Medicine （KIOM） International Symposium of Current Research Trends in Traditional Medicine - Pattern of Identification （2013）. In designing clinical studies, it is a research question that leads to appropriate study design. However, they are mostly diagnostic procedures and techniques that are the key points to reflect the application of systems and methods in all forms of medicine - traditional East Asian medicine （TEAM） is no exception. The challenges within TEAM based on research reflect in different systems of medicine/theories such as traditional Japanese acupuncture, traditional Korean acupuncture and traditional Chinese acupuncture. This diversitv of medical svstems and methods applied in East Asia seems to have beenfruitful within the different countries and traditional medicines have found their places within the respective countries health systems. The existing diversity, from a clinician＇s point of view, may be viewed as a treasure when dealing with patients in the ＇real world＇. On the other hand, this diversity seems to challenge the scientific mind worldwide, esoeciallv when it comes to research. Hence. there is a and between clinical practice and research.展开更多
An international brainstorming session on standardizing pattern identification（PI） was held at the Korea Institute of Oriental Medicine on October 1, 2013 in Daejeon, South Korea. This brainstorming session was conv...An international brainstorming session on standardizing pattern identification（PI） was held at the Korea Institute of Oriental Medicine on October 1, 2013 in Daejeon, South Korea. This brainstorming session was convened to gather insights from international traditional East Asian medicine specialists regarding PI standardization. With eight presentations and discussion sessions, the meeting allowed participants to discuss research methods and diagnostic systems used in traditional medicine for PI. One speaker presented a talk titled ＂The diagnostic criteria for blood stasis syndrome： implications for standardization of PI＂. Four speakers presented on future strategies and objective measurement tools that could be used in PI research. Later, participants shared information and methodology for accurate diagnosis and PI. They also discussed the necessity for standardizing PI and methods for international collaborations in pattern research.展开更多
A symposium on pattern identification（PI）was held at the Korea Institute of Oriental Medicine（KIOM）on October 2,2013,in Daejeon,South Korea.This symposium was convened to provide information on the current researc...A symposium on pattern identification（PI）was held at the Korea Institute of Oriental Medicine（KIOM）on October 2,2013,in Daejeon,South Korea.This symposium was convened to provide information on the current research in PI as well as suggest future research directions.The participants discussed the nature of PI,possible research questions,strategies and future international collaborations in pattern research.With eight presentations and an extensive panel discussion,the symposium allowed participants to discuss research methods in traditional medicine for PI.One speaker presented the topic,＇Clinical pattern differentiation and contemporary research in PI.＇Two speakers presented current trends in research on blood stasis while the remaining five other delegates discussed the research methods and future directions of PI research.The participants engaged in in-depth discussions regarding the nature of PI,potential research questions,strategies and future international collaborations in pattern research.展开更多
基金supported by the Korea Institute of Oriental Medicine(Nos.KSN2121211 and KSN23314112)LSW was supported by the National Center for Complementary and Integrative Health of the National Institutes of Health(No.R24 AT001293)The funders had no role in the design and conduct of the study,the collection,management,analysis,and interpretation of the data,the preparation,review,and approval of the manuscript,or the decision to submit the manuscript for publication.
文摘Various acupuncture clinical trials have been conducted on migraine;however,the conclusions remain controversial especially when acupuncture was compared with sham acupuncture.Sham acupuncture is sometimes performed at the same acupuncture points used for verum acupuncture despite the evidence on acupuncture point specificity.Four databases were searched for sham acupuncture or waiting list-controlled acupuncture trials for migraine on December 25,2023.Sham acupuncture was classified according to the needling points:sham acupuncture therapy at verum points(SATV)or at sham points(SATS).Network meta-analysis was performed based on the frequentist framework for headache pain intensity and response rate.A total of 18 studies involving 1936 participants were analyzed.Headache pain intensity and response rate were significantly improved in verum acupuncture compared with SATS.However,there was no significant difference between SATV and verum acupuncture.When comparing SATS and SATV,there was no significant difference in headache pain intensity and response rate;however,the results were in favor of SATV.The effect of the risk of bias on the certainty of evidence between verum and sham acupunctures was judged to be generally low.SATV should not be misused as a placebo control to evaluate the efficacy of acupuncture.
文摘Research into the diagnostic methods and patterns of traditional East Asian medical （TEAM） systems of practice such as acupuncture and herbal medicine face certain challenges due to the nature of thinking in TEAM and the subjective basis of judgments made in practice. The TEAM-based diagnosis can take into account various findings and signs such as the appearance of the tongue, palpable qualities of the radial pulses, palpable qualities and findings on the abdomen, the complexion of the patient and so on. Both diagnostic findings and the patterns of diagnosis cannot be assumed to have objective bases or to be causally related to the complaints of the patient. However, the diagnoses of TEAM based acupuncture and herbal medicine have tended to look at pictures of the whole patient and rather than focus on a particular symptom, they have looked across a myriad of signs and symptoms to decide or identify the ＇pattern＇ of diagnosis according to the theory in question. Although open for selective and subjective biases each diagnosis pattern always comes with a prescribed treatment tailored to the pattern. Further, the same research requirements needed for the validation of the diagnoses are needed also for these clinical observations and judgments. Hence, it is necessary, albeit challenging for research on TEAM diagnoses to first address these issues before proceeding to more complex investigations such as the development of instruments for making diagnostic observations, instruments for forming diagnostic conclusions or studies investigating the physiological bases of the diagnostic patterns. Preliminary work has started and instruments have been made, but we suggest that any instrumentation must necessarily be first validated by matching of the calibrated or scaled observations or judgments to observations made and agreed upon by relevant experts. Reliability of all observations and judgments are needed before any other tool, technology or more advanced approach can proceed and also whenever the natural system of diagnosis-treatment is applied in clinical trials. In this paper the authors highlight the core problems and describe a step wise process for addressing them.
基金the Norwegian Research Council and the Eckbos Legacy for funding the study
文摘Objective： To explore the correlation between single acupoints used and the recurrence rate of cystitis among cystitis-prone women receiving acupuncture as a prophylactic treatment. Methods： In all, 58 cystitis-prone women were included in the analysis. Customised acupuncture treatments were given twice a week, over 4 weeks. The main effect parameter was the number of cystitis episodes during the 6-month observation time. Residual urine was measured at baseline, 2, 4 and 6 months using portable ultrasound equipment. Sympathetic and vagotone nerve activities were measured by using skin conductance and respiratory sinus arrhythmia, respectively. Results： The main acupoints used for patients with Kidney （Shen） qi/yang deficiency were Shenshu （BL23）, Taixi （KI3）, Zhongji （CV3）, Sanyinjiao （SP6） and Pangguangshu （BL2.8）, compared with Taichong （LR3）, CV3, BL28, Yinlingquan （SP9） and SP6 for Liver （Gan） qi stagnation, and SP6, CV3, BL28, Zusanli （ST36） and SP9 for Spleen （Pi） qi/yang deficiency patients. The combination BL23 and KI3 were used in 16 women, 13 of which were Kidney pattern related patients. When used, the number of symptomatic episodes were reduced to a third compared with what occurred in the 42 women where this combination was not used （3/16 vs. 28/42, P〈0.05）. BL23 application correlated to a significant reduction in residual urine measured a few days after treatment. Patients with the pattern of Spleen qi/yang deficiency had an initial increase in residual urine after treatments. Conclusion： Treating Kidney pattern related patients with the combination of BL23 and KI3 resulted in far better outcome than other points/combination of points for other Chinese medicine diagnoses. The acupoint SP6 may be less indicated than previously assumed when treating cvstitis-Drone women DroDhvlacticalIv.
文摘This article is based on two presentations held at Chinese medicine conference in Rothenburg （2013）, Germany and at the 19th Anniversary of Korean Institute of Oriental Medicine （KIOM） International Symposium of Current Research Trends in Traditional Medicine - Pattern of Identification （2013）. In designing clinical studies, it is a research question that leads to appropriate study design. However, they are mostly diagnostic procedures and techniques that are the key points to reflect the application of systems and methods in all forms of medicine - traditional East Asian medicine （TEAM） is no exception. The challenges within TEAM based on research reflect in different systems of medicine/theories such as traditional Japanese acupuncture, traditional Korean acupuncture and traditional Chinese acupuncture. This diversitv of medical svstems and methods applied in East Asia seems to have beenfruitful within the different countries and traditional medicines have found their places within the respective countries health systems. The existing diversity, from a clinician＇s point of view, may be viewed as a treasure when dealing with patients in the ＇real world＇. On the other hand, this diversity seems to challenge the scientific mind worldwide, esoeciallv when it comes to research. Hence. there is a and between clinical practice and research.
文摘An international brainstorming session on standardizing pattern identification（PI） was held at the Korea Institute of Oriental Medicine on October 1, 2013 in Daejeon, South Korea. This brainstorming session was convened to gather insights from international traditional East Asian medicine specialists regarding PI standardization. With eight presentations and discussion sessions, the meeting allowed participants to discuss research methods and diagnostic systems used in traditional medicine for PI. One speaker presented a talk titled ＂The diagnostic criteria for blood stasis syndrome： implications for standardization of PI＂. Four speakers presented on future strategies and objective measurement tools that could be used in PI research. Later, participants shared information and methodology for accurate diagnosis and PI. They also discussed the necessity for standardizing PI and methods for international collaborations in pattern research.
基金supported by Korea Institute of Oriental Medicine (K13130 and K13281)
文摘A symposium on pattern identification（PI）was held at the Korea Institute of Oriental Medicine（KIOM）on October 2,2013,in Daejeon,South Korea.This symposium was convened to provide information on the current research in PI as well as suggest future research directions.The participants discussed the nature of PI,possible research questions,strategies and future international collaborations in pattern research.With eight presentations and an extensive panel discussion,the symposium allowed participants to discuss research methods in traditional medicine for PI.One speaker presented the topic,＇Clinical pattern differentiation and contemporary research in PI.＇Two speakers presented current trends in research on blood stasis while the remaining five other delegates discussed the research methods and future directions of PI research.The participants engaged in in-depth discussions regarding the nature of PI,potential research questions,strategies and future international collaborations in pattern research.
