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A One Health approach to fight antimicrobial resistance in Uganda: Implementation experience, results, and lessons learned
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作者 reuben kiggundu J.P.Waswa +12 位作者 Niranjan Konduri Hassan Kasuja Marion Murungi Patrick Vudriko Harriet Akello Eric Lugada Cecilia Muiva Esther Were Dinah Tjipura Henry Kajumbula Kate Kikule Emmanuel Nfor Mohan P.Joshi 《Biosafety and Health》 CAS CSCD 2024年第2期125-132,共8页
Uganda has been implementing the Global Health Security Agenda(GHSA)since 2015 to build its capacity according to World Health Organization(WHO)Benchmarks on International Health Regulations Capacities.The country rem... Uganda has been implementing the Global Health Security Agenda(GHSA)since 2015 to build its capacity according to World Health Organization(WHO)Benchmarks on International Health Regulations Capacities.The country remains prone to outbreaks,with more than 20 disease outbreaks reported in the past five years,including Ebola virus disease,Crimean-Congo haemorrhagic fever,Marburg haemorrhagic fever,measles,yellow fever,coronavirus disease 2019(COVID-19),and cholera.Antimicrobial resistance(AMR)is an ongoing challenge.Uganda scored capacity level 3 on infection prevention and control(IPC)and antimicrobial stewardship(AMS)in the 2017 Joint External Evaluation(JEE)assessment.Identified gaps were being addressed after a self-assessment in 2021.This paper describes the technical assistance approaches provided to Uganda by the Medicines,Technologies,and Pharmaceutical Services Program,funded by the United States(U.S.)Agency for International Development,and implemented by Management Sciences for Health.The program,through a One Health approach,supported systematic capacity strengthening based on the JEE's capacity advancement framework for global health security,specifically relating to AMR.The program's interventions impacted 32 WHO benchmark actions(7 for AMR multisectoral coordination,16 for IPC,and 9 for AMS),contributing to Uganda's strengthened GHSA capacity.Leveraging success built on the AMR platform,the program trained 745 health workers in IPC for the Ebola virus and provided support for simulation exercises by eight district IPC teams.The program also worked with the Ministry of Health to coordinate IPC for the COVID-19 response in five health regions,covering 45 districts and reaching 5,452 health workers at 858 health facilities. 展开更多
关键词 One health Antimicrobial resistance Antibiotic resistance Jointexternal evaluation Global health security Uganda AFRICA WHO Benchmarks for International Health Regulations Capacities
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A bottom-up,One Health approach to assessing progress in the implementation of a national action plan for combatting antimicrobial resistance:a case study from Uganda
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作者 J.P.Waswa reuben kiggundu +8 位作者 Hassan Kasujja Patrick Vudriko Hakim Sendagire Henry Kajumbula Musa Sekamatte Francis Kakooza Fozo Alombah Mohan P.Joshi Niranjan Konduri 《One Health Advances》 2024年第1期95-110,共16页
Antimicrobial resistance(AMR)is one of the greatest threats to public health,and it is spreading across the human health,animal health,and environmental sectors.Sole reliance on desk reviews and national-level stakeho... Antimicrobial resistance(AMR)is one of the greatest threats to public health,and it is spreading across the human health,animal health,and environmental sectors.Sole reliance on desk reviews and national-level stakeholder engagement carries a risk of overestimating the country’s health security and AMR capacity.For a genuine evalua-tion,engaging frontline and last-mile implementers such as health care facilities and workers,farmers,and district local governments ensures a more accurate assessment of existing capabilities and implementation progress.Uganda utilized a bottom-up approach to assess the implementation status of the National Action Plan on AMR(NAP-AMR)to ensure the engagement of key stakeholders at the subnational level,who are often overlooked in NAP-AMR evalu-ation initiatives.This review revealed poor engagement of subnational stakeholders in the development,validation,dissemination,and implementation of the NAP-AMR as well as various issues at the national level—including gaps in government One Health policy,insufficient funding,and ineffective coordination—that resulted in the inadequate implementation of the NAP-AMR.Addressing these challenges should involve establishing a One Health policy and identifying sustainable funding sources for AMR activities.We recommend the legislation of dedicated policy to formally incorporate the National One Health Platform into government structures at the national and subnational levels.In our experience,a bottom-up approach to evaluating NAP-AMR implementation enhances the effective-ness of the review process and could be utilized by the WHO during the joint external evaluation of health security capacity. 展开更多
关键词 Antimicrobial resistance National Action Plan Global Action Plan One Health Uganda AFRICA
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