<strong>Background:</strong><span style="font-family:Verdana;"> Post-operative breast radiotherapy is used to reduce recurrence</span><span style="font-family:"">...<strong>Background:</strong><span style="font-family:Verdana;"> Post-operative breast radiotherapy is used to reduce recurrence</span><span style="font-family:""><span style="font-family:Verdana;">. </span><span style="font-family:Verdana;">The aim of this study was</span><span style="font-family:Verdana;"> to investigate the outcomes of </span><span style="font-family:Verdana;">Deep</span><span style="font-family:Verdana;"> Inspiration Breath-Hold (DIBH) technique with indigenous </span><span style="font-family:Verdana;">breath holding</span><span style="font-family:Verdana;"> indicator scale in 3DCRT for breast cancer radiotherapy over </span><span style="font-family:Verdana;">Free</span><span style="font-family:Verdana;"> Breathing (FB) technique. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> An observational study </span><span style="font-family:Verdana;">conducted</span> </span><span style="font-family:""><span style="font-family:Verdana;">at the </span><span style="font-family:Verdana;">Department</span><span style="font-family:Verdana;"> of Radiation Oncology </span></span><span style="font-family:""><span style="font-family:Verdana;">at </span><span style="font-family:Verdana;">National</span><span style="font-family:Verdana;"> Institute of Cancer Research and Hospital, Dhaka and Square Hospital Limited, Dhaka, Bangladesh from June 2015 to May 2016. A total of 60</span></span><span style="font-family:""><span style="font-family:Verdana;"> confirmed breast cancer patients who underwent adjuvant radiotherapy were included. An indigenous reproducible plastic tool (Perspex) was used as </span><span style="font-family:Verdana;">breath holding</span><span style="font-family:Verdana;"> indicator scale with </span></span><span style="font-family:Verdana;">DIBH</span><span style="font-family:""><span style="font-family:Verdana;"> technique in 3DCRT</span><i><span style="font-family:Verdana;">. </span></i><span><span style="font-family:Verdana;">Paired sample t-test was used to compare with </span><span style="font-family:Verdana;">FB</span><span style="font-family:Verdana;"> technique. </span><b><span style="font-family:Verdana;">Results:</span></b><i> </i><span style="font-family:Verdana;">The mean age of patients </span><span style="font-family:Verdana;">w</span></span></span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> 47.32 (SD ± 8.33) years.</span><span style="font-family:""><span style="font-family:Verdana;"> In </span><span style="font-family:Verdana;">FB</span><span style="font-family:Verdana;"> technique, Mean Heart Dose (MHD) was 413.27 cGy while in </span><span style="font-family:Verdana;">DIBH</span><span style="font-family:Verdana;"> technique, it was 254.91 cGy (P < 0.001). The mean heart V20</span></span><span style="font-family:Verdana;"> and </span><span style="font-family:""><span style="font-family:Verdana;">V30 </span><span style="font-family:Verdana;">were</span><span style="font-family:Verdana;"> 5.5%, 4.37%</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">in FB and</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">3.13%, 2.36% in DIBH respectively. In </span><span style="font-family:Verdana;">FB</span><span style="font-family:Verdana;"> technique LADMD, LAD</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">0.2</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">cm</span><sup><span style="font-family:Verdana;">3</span></sup><span style="font-family:Verdana;">, ILMD </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> ILV20 </span><span style="font-family:Verdana;">w</span></span><span style="font-family:Verdana;">ere</span><span style="font-family:Verdana;"> 1698.17</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">cGy, 2852.53 cGy, 1155.31 cGy </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> 28.62% while in </span><span style="font-family:Verdana;">DIBH</span><span style="font-family:Verdana;"> technique, it was reduced to 1164.01 cGy, 2132.24 cGy, 1007.98 cGy and 23.39% respectively. Similarly, the lung-CLMD and breast-CLMD </span><span style="font-family:Verdana;">w</span></span><span style="font-family:Verdana;">ere</span><span style="font-family:""><span style="font-family:Verdana;"> reduced from 38.37 cGy and 55.18 cGy to 24.64 cGy and 33.82 cGy respectively (P < 0.001). The mean difference for breast-CLMD was 21.36 cGy. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The use of indigenous </span><span style="font-family:Verdana;">breath holding</span><span style="font-family:Verdana;"> indicator scale with DIBH had better outcomes on breast cancer radiotherapy.</span></span>展开更多
文摘<strong>Background:</strong><span style="font-family:Verdana;"> Post-operative breast radiotherapy is used to reduce recurrence</span><span style="font-family:""><span style="font-family:Verdana;">. </span><span style="font-family:Verdana;">The aim of this study was</span><span style="font-family:Verdana;"> to investigate the outcomes of </span><span style="font-family:Verdana;">Deep</span><span style="font-family:Verdana;"> Inspiration Breath-Hold (DIBH) technique with indigenous </span><span style="font-family:Verdana;">breath holding</span><span style="font-family:Verdana;"> indicator scale in 3DCRT for breast cancer radiotherapy over </span><span style="font-family:Verdana;">Free</span><span style="font-family:Verdana;"> Breathing (FB) technique. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> An observational study </span><span style="font-family:Verdana;">conducted</span> </span><span style="font-family:""><span style="font-family:Verdana;">at the </span><span style="font-family:Verdana;">Department</span><span style="font-family:Verdana;"> of Radiation Oncology </span></span><span style="font-family:""><span style="font-family:Verdana;">at </span><span style="font-family:Verdana;">National</span><span style="font-family:Verdana;"> Institute of Cancer Research and Hospital, Dhaka and Square Hospital Limited, Dhaka, Bangladesh from June 2015 to May 2016. A total of 60</span></span><span style="font-family:""><span style="font-family:Verdana;"> confirmed breast cancer patients who underwent adjuvant radiotherapy were included. An indigenous reproducible plastic tool (Perspex) was used as </span><span style="font-family:Verdana;">breath holding</span><span style="font-family:Verdana;"> indicator scale with </span></span><span style="font-family:Verdana;">DIBH</span><span style="font-family:""><span style="font-family:Verdana;"> technique in 3DCRT</span><i><span style="font-family:Verdana;">. </span></i><span><span style="font-family:Verdana;">Paired sample t-test was used to compare with </span><span style="font-family:Verdana;">FB</span><span style="font-family:Verdana;"> technique. </span><b><span style="font-family:Verdana;">Results:</span></b><i> </i><span style="font-family:Verdana;">The mean age of patients </span><span style="font-family:Verdana;">w</span></span></span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> 47.32 (SD ± 8.33) years.</span><span style="font-family:""><span style="font-family:Verdana;"> In </span><span style="font-family:Verdana;">FB</span><span style="font-family:Verdana;"> technique, Mean Heart Dose (MHD) was 413.27 cGy while in </span><span style="font-family:Verdana;">DIBH</span><span style="font-family:Verdana;"> technique, it was 254.91 cGy (P < 0.001). The mean heart V20</span></span><span style="font-family:Verdana;"> and </span><span style="font-family:""><span style="font-family:Verdana;">V30 </span><span style="font-family:Verdana;">were</span><span style="font-family:Verdana;"> 5.5%, 4.37%</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">in FB and</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">3.13%, 2.36% in DIBH respectively. In </span><span style="font-family:Verdana;">FB</span><span style="font-family:Verdana;"> technique LADMD, LAD</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">0.2</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">cm</span><sup><span style="font-family:Verdana;">3</span></sup><span style="font-family:Verdana;">, ILMD </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> ILV20 </span><span style="font-family:Verdana;">w</span></span><span style="font-family:Verdana;">ere</span><span style="font-family:Verdana;"> 1698.17</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">cGy, 2852.53 cGy, 1155.31 cGy </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> 28.62% while in </span><span style="font-family:Verdana;">DIBH</span><span style="font-family:Verdana;"> technique, it was reduced to 1164.01 cGy, 2132.24 cGy, 1007.98 cGy and 23.39% respectively. Similarly, the lung-CLMD and breast-CLMD </span><span style="font-family:Verdana;">w</span></span><span style="font-family:Verdana;">ere</span><span style="font-family:""><span style="font-family:Verdana;"> reduced from 38.37 cGy and 55.18 cGy to 24.64 cGy and 33.82 cGy respectively (P < 0.001). The mean difference for breast-CLMD was 21.36 cGy. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The use of indigenous </span><span style="font-family:Verdana;">breath holding</span><span style="font-family:Verdana;"> indicator scale with DIBH had better outcomes on breast cancer radiotherapy.</span></span>
