基金This work was supported by the National Key Research and Development Program of China （No. 2016YFC0902800）, National Natural Science Foundation of China （Nos. 81230055 and 81530006 to Ruibao Ren）, and the Samuel Waxman Cancer Research Foudation Co-PI Program. We thank Huanbin Zhao, Min Wu, Chun Zhang, Mingzhu Liu, Zhangsen Huang, and Lingyun Tang for technical assistance.
