Crystallization is a fundamental separation technology used for the production of particulate solids.Accurate nucleation and growth process control are vitally important but difficult.A novel controlling technology th...Crystallization is a fundamental separation technology used for the production of particulate solids.Accurate nucleation and growth process control are vitally important but difficult.A novel controlling technology that can simultaneously intensify the overall crystallization process remains a significant challenge.Membrane crystallization(MCr),which has progressed significantly in recent years,is a hybrid technology platform with great potential to address this goal.This review illustrates the basic concepts of MCr and its promising applications for crystallization control and process intensification,including a state-of-the-art review of key MCr-utilized membrane materials,process control mechanisms,and optimization strategies based on diverse hybrid membranes and crystallization processes.Finally,efforts to promote MCr technology to industrial use,unexplored issues,and open questions to be addressed are outlined.展开更多
Development of novel vaccine deliveries and vaccine adjuvants is of great importance to address the dilemma that the vaccine field faces:to improve vaccine efficacy without compromising safety.Harnessing the specific ...Development of novel vaccine deliveries and vaccine adjuvants is of great importance to address the dilemma that the vaccine field faces:to improve vaccine efficacy without compromising safety.Harnessing the specific effects of laser on biological systems,a number of novel concepts have been proposed and proved in recent years to facilitate vaccination in a safer and more efficient way.The key advantage of using laser technology in vaccine delivery and adjuvantation is that all processes are initiated by physical e®ects with no foreign chemicals administered into the body.Here,we review the recent advances in using laser technology to facilitate vaccine delivery and augment vaccine efficacy as well as the underlying mechanisms.展开更多
Purpose The purpose of this work is to develop a novel pattern tracking algorithm to be used on the detectors of the future electron-positron colliders.Method ArborTracking,a light-weighted tracking algorithm,has been...Purpose The purpose of this work is to develop a novel pattern tracking algorithm to be used on the detectors of the future electron-positron colliders.Method ArborTracking,a light-weighted tracking algorithm,has been developed based on the tree topology of track clusters and applied to the baseline detector of the circular electron-positron collider(CEPC).The algorithm collects all the hits in the tracker as a tree(forest),splits the tree branches to form the track segments,and merges the track segments to form the tracks.Results Compared with the general track following method,the algorithm has the advantages of low coding complicity and low CPU cost.The performances at different benchmarks are studied.The results are exhaustively listed showing that the method is approaching the limit of the detector.The tracking efficiencies on single muon sample and three-prong sample are both higher than 99%.The transverse momentum resolution reaches 0.1%level and the boson mass resolution reaches 4.7 GeV/c.Conclusions The performances are similar with those of the baseline tracking algorithm of CEPC,and the physics requirement of CEPC is satisfied.The new tree pattern recognition algorithm is a necessary part in the CEPC software.And it is also a competitive algorithm on the market,which can be chosen by the future experiments.展开更多
Cooling crystallization is an important separation process and particuology technology that requires accurate nucleation control strategies.Herein,we introduced the polymeric hollow fiber membrane with proper thermal ...Cooling crystallization is an important separation process and particuology technology that requires accurate nucleation control strategies.Herein,we introduced the polymeric hollow fiber membrane with proper thermal properties as the effective nucleation induction interface during cooling crystallization.The heterogeneous nucleation control mechanism was introduced based on classical nucleation theory and the thermal transfer process.Interfacial properties and the thermal conductivity of two kinds of polymeric membranes,polytetrafluoroethylene(PTFE)and polyethersulfone(PES),were measured and simulated with the developed model.These two membranes possessed different nucleation induction periods,nucleation rates and crystallization performances,which validated that the hollow fiber membrane module could effectively accelerate the nucleation process compared to conventional cooling crystallization owing to the shorter nucleation induction period and the reduced solution surface tension.Due to the higher hydrophobicity and the lower roughness of the membrane surface,the PTFE membrane possessed a more moderate performance in generating stable heterogeneous nucleation than the one of PES membrane.Thus,the adjustable membrane property enabled the hollow fiber membrane-assisted cooling crystallization to possess the accurate nucleation control and desired terminal particle products.展开更多
In the steelmaking industry,enhancing production cost-effectiveness and operational efficiency requires the integration of intelligent systems to support production activities.Thus,effectively integrating various prod...In the steelmaking industry,enhancing production cost-effectiveness and operational efficiency requires the integration of intelligent systems to support production activities.Thus,effectively integrating various production modules is crucial to enable collaborative operations throughout the entire production chain,reducing management costs and complexities.This paper proposes,for the first time,the integration of Vision-Language Model(VLM)and Large Language Model(LLM)technologies in the steel manufacturing domain,creating a novel steelmaking process management system.The system facilitates data collection,analysis,visualization,and intelligent dialogue for the steelmaking process.The VLM module provides textual descriptions for slab defect detection,while LLM technology supports the analysis of production data and intelligent question-answering.The feasibility,superiority,and effectiveness of the system are demonstrated through production data and comparative experiments.The system has significantly lowered costs and enhanced operational understanding,marking a critical step toward intelligent and cost-effective management in the steelmaking domain.展开更多
Partially blind signatures are introduced on the basis of blind signatures,which not only retain the advantages of blind signatures,but also solve the contradiction between anonymity and controllability in blind signa...Partially blind signatures are introduced on the basis of blind signatures,which not only retain the advantages of blind signatures,but also solve the contradiction between anonymity and controllability in blind signatures.With the development of quantum computing technology,it becomes more urgent to construct secure partially blind signature schemes in quantum environments.In this paper,we present a new partially blind signature scheme and prove the security under the Ring-SIS assumption in the random oracle model.To avoid the restart problem of signature schemes caused by rejection sampling,a large number of random numbers are sampled in advance,so that they only need to be re-selected at the current stage without terminating the whole signature process when the conditions are not met.In addition,the hash tree technology is used to reduce communication costs and improve interactive performance.In order to avoid the errors in the security proof of the previous scheme,our proof builds upon and extends the modular framework for blind signatures of Hauck et al.and the correctness,partial blindness,and one-more unforgeability of the scheme are proved in detail according to the properties of the linear hash function.展开更多
Calixarenes and pillararenes are cyclic oligomers containing repeating units of phenol and methane. The modification of ionized groups bring calixarenes and pillararenes derivates both good water solubility and strong...Calixarenes and pillararenes are cyclic oligomers containing repeating units of phenol and methane. The modification of ionized groups bring calixarenes and pillararenes derivates both good water solubility and strong binding affinities towards various organic/inorganic/biological vip molecules in both water and the solid state. Meanwhile, the pre-organized structures of these compounds are indispensable in constructing of stimuli-responsive supramolecular assembly. With these properties, the supramolecular selective binding and molecular assembly based on calixarene/pillararene are widely used in enzyme tandem assay, stimuli-responsive nanostructure, drug delivery, organelle fluorescent imaging, photo-controlled morphological change, organic and inorganic hybrid material, solid tunable photo-luminescence and so on. This review summarized the recent research progresses on the calixarene/pillararene-based supramolecular systems and discussed the expectation of the future development.展开更多
基金We acknowledge the financial contributions from the National Natural Science Foundation of China(21978037,21676043,21527812,and U1663223)the Ministry of Science and Technology of the People’s Republic of China innovation team in key area(2016RA4053)Fundamental Research Funds for the Central Universities(DUT19TD33).
文摘Crystallization is a fundamental separation technology used for the production of particulate solids.Accurate nucleation and growth process control are vitally important but difficult.A novel controlling technology that can simultaneously intensify the overall crystallization process remains a significant challenge.Membrane crystallization(MCr),which has progressed significantly in recent years,is a hybrid technology platform with great potential to address this goal.This review illustrates the basic concepts of MCr and its promising applications for crystallization control and process intensification,including a state-of-the-art review of key MCr-utilized membrane materials,process control mechanisms,and optimization strategies based on diverse hybrid membranes and crystallization processes.Finally,efforts to promote MCr technology to industrial use,unexplored issues,and open questions to be addressed are outlined.
基金This work is supported in part by the National Institutes of Health grants AI089779,AI070785,AI097696 and DA028378 (to M.X.W.)the National Institutes of Health grants DA033371,AI107678 (to X.Y.C).
文摘Development of novel vaccine deliveries and vaccine adjuvants is of great importance to address the dilemma that the vaccine field faces:to improve vaccine efficacy without compromising safety.Harnessing the specific effects of laser on biological systems,a number of novel concepts have been proposed and proved in recent years to facilitate vaccination in a safer and more efficient way.The key advantage of using laser technology in vaccine delivery and adjuvantation is that all processes are initiated by physical e®ects with no foreign chemicals administered into the body.Here,we review the recent advances in using laser technology to facilitate vaccine delivery and augment vaccine efficacy as well as the underlying mechanisms.
基金supported by the Continuous Basic Scientific Research Project(No.WDJC-2019-16)National Key Research and Development Project(2018YFE0104800,2016YFE0100900,2016 YFA0400300)National Natural Science Foundation of China(11775313)
文摘Purpose The purpose of this work is to develop a novel pattern tracking algorithm to be used on the detectors of the future electron-positron colliders.Method ArborTracking,a light-weighted tracking algorithm,has been developed based on the tree topology of track clusters and applied to the baseline detector of the circular electron-positron collider(CEPC).The algorithm collects all the hits in the tracker as a tree(forest),splits the tree branches to form the track segments,and merges the track segments to form the tracks.Results Compared with the general track following method,the algorithm has the advantages of low coding complicity and low CPU cost.The performances at different benchmarks are studied.The results are exhaustively listed showing that the method is approaching the limit of the detector.The tracking efficiencies on single muon sample and three-prong sample are both higher than 99%.The transverse momentum resolution reaches 0.1%level and the boson mass resolution reaches 4.7 GeV/c.Conclusions The performances are similar with those of the baseline tracking algorithm of CEPC,and the physics requirement of CEPC is satisfied.The new tree pattern recognition algorithm is a necessary part in the CEPC software.And it is also a competitive algorithm on the market,which can be chosen by the future experiments.
基金support from National Natural Science Foundation of China(grant No.22021005,22378041)National Key Research and Development Program of China(grant No.2021YFC2901300)+3 种基金Central Guidance on Local Science and Technology Development Fund of Liaoning Province(grant No.2023JH6/100100004)Fundamental Research Fundamental Funds for the Central Universities(grant No.DUT22LAB603,DUT22QN209)Key Research and Development Projects in Shandong Province(grant No.2022CXGC010303)acknowledge the assistance of DUT Instrumental Analysis Center.
文摘Cooling crystallization is an important separation process and particuology technology that requires accurate nucleation control strategies.Herein,we introduced the polymeric hollow fiber membrane with proper thermal properties as the effective nucleation induction interface during cooling crystallization.The heterogeneous nucleation control mechanism was introduced based on classical nucleation theory and the thermal transfer process.Interfacial properties and the thermal conductivity of two kinds of polymeric membranes,polytetrafluoroethylene(PTFE)and polyethersulfone(PES),were measured and simulated with the developed model.These two membranes possessed different nucleation induction periods,nucleation rates and crystallization performances,which validated that the hollow fiber membrane module could effectively accelerate the nucleation process compared to conventional cooling crystallization owing to the shorter nucleation induction period and the reduced solution surface tension.Due to the higher hydrophobicity and the lower roughness of the membrane surface,the PTFE membrane possessed a more moderate performance in generating stable heterogeneous nucleation than the one of PES membrane.Thus,the adjustable membrane property enabled the hollow fiber membrane-assisted cooling crystallization to possess the accurate nucleation control and desired terminal particle products.
文摘In the steelmaking industry,enhancing production cost-effectiveness and operational efficiency requires the integration of intelligent systems to support production activities.Thus,effectively integrating various production modules is crucial to enable collaborative operations throughout the entire production chain,reducing management costs and complexities.This paper proposes,for the first time,the integration of Vision-Language Model(VLM)and Large Language Model(LLM)technologies in the steel manufacturing domain,creating a novel steelmaking process management system.The system facilitates data collection,analysis,visualization,and intelligent dialogue for the steelmaking process.The VLM module provides textual descriptions for slab defect detection,while LLM technology supports the analysis of production data and intelligent question-answering.The feasibility,superiority,and effectiveness of the system are demonstrated through production data and comparative experiments.The system has significantly lowered costs and enhanced operational understanding,marking a critical step toward intelligent and cost-effective management in the steelmaking domain.
基金supported in part by the Key Research and Development Program of Shaanxi(2021 ZDLGY06-04)in part by the Youth Innovation Team of Shaanxi Universities.The review of this article was coordinated by Dr.Changyu Dong.
文摘Partially blind signatures are introduced on the basis of blind signatures,which not only retain the advantages of blind signatures,but also solve the contradiction between anonymity and controllability in blind signatures.With the development of quantum computing technology,it becomes more urgent to construct secure partially blind signature schemes in quantum environments.In this paper,we present a new partially blind signature scheme and prove the security under the Ring-SIS assumption in the random oracle model.To avoid the restart problem of signature schemes caused by rejection sampling,a large number of random numbers are sampled in advance,so that they only need to be re-selected at the current stage without terminating the whole signature process when the conditions are not met.In addition,the hash tree technology is used to reduce communication costs and improve interactive performance.In order to avoid the errors in the security proof of the previous scheme,our proof builds upon and extends the modular framework for blind signatures of Hauck et al.and the correctness,partial blindness,and one-more unforgeability of the scheme are proved in detail according to the properties of the linear hash function.
基金the National Natural Science Foundation of China (Nos. 21672113, 21432004, 21772099,21861132001)
文摘Calixarenes and pillararenes are cyclic oligomers containing repeating units of phenol and methane. The modification of ionized groups bring calixarenes and pillararenes derivates both good water solubility and strong binding affinities towards various organic/inorganic/biological vip molecules in both water and the solid state. Meanwhile, the pre-organized structures of these compounds are indispensable in constructing of stimuli-responsive supramolecular assembly. With these properties, the supramolecular selective binding and molecular assembly based on calixarene/pillararene are widely used in enzyme tandem assay, stimuli-responsive nanostructure, drug delivery, organelle fluorescent imaging, photo-controlled morphological change, organic and inorganic hybrid material, solid tunable photo-luminescence and so on. This review summarized the recent research progresses on the calixarene/pillararene-based supramolecular systems and discussed the expectation of the future development.
