The purpose of this study was to explore whether genomic polymorphisms in the alpha 1（XI）collagen gene（COL11A1）were associated with the risk and severity of Kashin-Beck disease（KBD）.
To understand how differentially methylated genes（DMGs）might affect the pathogenesis of Kashin-Beck disease（KBD）.Genome-wide methylation profiling of whole blood from 12matched KBD and controls pairs was performed...To understand how differentially methylated genes（DMGs）might affect the pathogenesis of Kashin-Beck disease（KBD）.Genome-wide methylation profiling of whole blood from 12matched KBD and controls pairs was performed using a high-resolution Infinium 450 K methylation array.In total,97 CpG sites were differentially展开更多
基金supported by grants from the National Natural Science Foundation of China[No.81273007No.81620108026]
文摘The purpose of this study was to explore whether genomic polymorphisms in the alpha 1（XI）collagen gene（COL11A1）were associated with the risk and severity of Kashin-Beck disease（KBD）.
基金supported by grants from the National Natural Science Foundation of China(No.81273007)
文摘To understand how differentially methylated genes（DMGs）might affect the pathogenesis of Kashin-Beck disease（KBD）.Genome-wide methylation profiling of whole blood from 12matched KBD and controls pairs was performed using a high-resolution Infinium 450 K methylation array.In total,97 CpG sites were differentially
