The development of science and technology,especially the rise of augmented reality(AR)technology provides a new way for the inheritance and innovation of traditional intangible cultural heritage.Based on the design an...The development of science and technology,especially the rise of augmented reality(AR)technology provides a new way for the inheritance and innovation of traditional intangible cultural heritage.Based on the design and research of the tide play blind box of AR digital technology empowering traditional intangible cultural heritage,this paper discusses the application and feasibility of AR technology in the traditional intangible cultural heritage,analyzes the strategy of implementing AR technology empowering intangible cultural heritage,and puts forward corresponding countermeasures for the challenges that may be faced,aiming at providing new ideas and methods for traditional intangible cultural heritage and modern science and technology.展开更多
High-power terahertz(THz)quantum cascade laser,as an emerging THz solid-state radiation source,is attracting attention for numerous applications including medicine,sensing,and communication.However,due to the subwavel...High-power terahertz(THz)quantum cascade laser,as an emerging THz solid-state radiation source,is attracting attention for numerous applications including medicine,sensing,and communication.However,due to the subwavelength confinement of the waveguide structure,direct beam brightness upscaling with device area remains elusive due to several mode competition and external optical lens is normally used to enhance the THz beam brightness.Here,we propose a metallic THz photonic crystal resonator with a phase-engineered design for single mode surface emission over a broad area.The quantum cascade surface-emitting laser is capable of delivering an output peak power over 185 mW with a narrow beam divergence of 4.4°×4.4°at 3.88 THz.A high beam brightness of 1.6×10^(7)W sr^(-1)m^(-2)with near-diffraction-limited M2 factors of 1.4 in both vertical and lateral directions is achieved from a large device area of 1.6×1.6 mm^(2)without using any optical lenses.The adjustable phase shift between the lattices enables a stable and high-intensity surface emission over a broad device area,which makes it an ideal light extractor for large-scale THz emitters.Our research paves the way to high brightness solid-state THz lasers and facilitates new applications in standoff THz imaging,detection,and diagnosis.展开更多
With the advent of the internet of things and artificial intelligence,flexible and portable pressure sensors have shown great application potential in human-computer interaction,personalized medicine and other fields....With the advent of the internet of things and artificial intelligence,flexible and portable pressure sensors have shown great application potential in human-computer interaction,personalized medicine and other fields.By comparison with traditional inorganic materials,flexible polymeric materials conformable to the human body are more suitable for the fabrication of wearable pressure sensors.Given the consumption of a huge amount of flexible wearable electronics in near future,it is necessary to turn their attention to biodegradable polymers for the fabrication of flexible pressure sensors toward the development requirement of green and sustainable electronics.In this paper,the structure and properties of silk fibroin(SF)are introduced,and the source and research progress of the piezoelectric properties of SF are systematically discussed.In addition,this paper summarizes the advance in the studies on SF-based capacitive,resistive,triboelectric,and piezoelectric sensors reported in recent years,and focuses on their fabrication methods and applications.Finally,this paper also puts forward the future development trend of high-efficiency fabrication and corresponding application of SF-based piezoelectric sensors.It offers new insights into the design and fabrication of green and biodegradable bioelectronics for in vitro and in vivo sensing applications.展开更多
Sugarcane is recognized as the fifth largest crop globally,supplying 80%of sugar and 40%of bioenergy production.However,sugarcane genetic research has significantly lagged behind other crops due to its complex genetic...Sugarcane is recognized as the fifth largest crop globally,supplying 80%of sugar and 40%of bioenergy production.However,sugarcane genetic research has significantly lagged behind other crops due to its complex genetic background,high ploidy(8-13×),aneuploidy,limited flowering,and a long growth cycle(more than one year).Cross breeding began in 1887 following the discovery that sugarcane seeds could germinate.Both self-and cross-pollination and selection were conducted by sugarcane breeders,but new cultivars were often eliminated due to disease susceptibility.Within the Saccharum genus,different species possess variable numbers of chromosomes.Wild sugarcane species intercrossed with each other,leading to development of the‘Nobilization’breeding strategy,which significantly improved yield,sucrose,fiber content,and disease resistance,and accelerated genetic improvement of cultivars.In recent years,scientific achievements have also been made in sugarcane genome sequencing,molecular marker development,genetic linkage map construction,localization of quantitative trait locus(QTL),and trait-associated gene identification.This review focuses on the progress in sugarcane genetic research,analyzes the technical difficulties faced,presents opportunities and challenges,and provides guidance and references for future sugarcane genetics research and cultivar breeding.Finally,it offers directions for future on sugarcane genetics.展开更多
Eight new water-soluble amino acid conjugates 6 a-h of chlorin p6 ethers(5 a-d) were synthesized and preliminarily investigated for their in vitro PDT antitumor activity and structure-activity relationship(SAR). The r...Eight new water-soluble amino acid conjugates 6 a-h of chlorin p6 ethers(5 a-d) were synthesized and preliminarily investigated for their in vitro PDT antitumor activity and structure-activity relationship(SAR). The results showed that all compounds exhibited much higher phototoxicity against tumor cells than talaporfin. SAR analysis indicated that PDT antitumor effect enhanced with the increase of carbon chain length of alkoxyl ether bonds at 3~1-position, and L-aspartic acid was superior to L-glutamic acid. In particular, the IC_50 values of most phototoxic compound 6 d were 0.20 mmol/L against A549 cell and0.41υmmol/L against B16-F10 cell, which individually represented 31-and 24-fold increase of antitumor potency compared to talaporfin, suggesting that it was a promising candidate photosensitizer(PS) for PDT applications due to its strong absorption at long wavelength, high phototoxicity, low dark cytotoxicity and good water-solubility.展开更多
基金College Students’Innovation and Entrepreneurship Training Project:Wanyue Innovation Tide Playing Blind Box Based on AR Digital Technology Empowering Traditional Intangible Cultural Heritage(Project number:2023092DCXM).
文摘The development of science and technology,especially the rise of augmented reality(AR)technology provides a new way for the inheritance and innovation of traditional intangible cultural heritage.Based on the design and research of the tide play blind box of AR digital technology empowering traditional intangible cultural heritage,this paper discusses the application and feasibility of AR technology in the traditional intangible cultural heritage,analyzes the strategy of implementing AR technology empowering intangible cultural heritage,and puts forward corresponding countermeasures for the challenges that may be faced,aiming at providing new ideas and methods for traditional intangible cultural heritage and modern science and technology.
基金supported by the National Natural Science Foundation of China(62274014,62235016)Bejing Municipal Science&Technology Commission(Z221100002722018).
文摘High-power terahertz(THz)quantum cascade laser,as an emerging THz solid-state radiation source,is attracting attention for numerous applications including medicine,sensing,and communication.However,due to the subwavelength confinement of the waveguide structure,direct beam brightness upscaling with device area remains elusive due to several mode competition and external optical lens is normally used to enhance the THz beam brightness.Here,we propose a metallic THz photonic crystal resonator with a phase-engineered design for single mode surface emission over a broad area.The quantum cascade surface-emitting laser is capable of delivering an output peak power over 185 mW with a narrow beam divergence of 4.4°×4.4°at 3.88 THz.A high beam brightness of 1.6×10^(7)W sr^(-1)m^(-2)with near-diffraction-limited M2 factors of 1.4 in both vertical and lateral directions is achieved from a large device area of 1.6×1.6 mm^(2)without using any optical lenses.The adjustable phase shift between the lattices enables a stable and high-intensity surface emission over a broad device area,which makes it an ideal light extractor for large-scale THz emitters.Our research paves the way to high brightness solid-state THz lasers and facilitates new applications in standoff THz imaging,detection,and diagnosis.
基金financial support from the National Natural Science Foundation of China(NNSFC Grants 52125301 and 52373269)he State Key Laboratory of Polymer Materials Engineering of Sichuan University(Grant No.:sklpme2022-3-06)。
文摘With the advent of the internet of things and artificial intelligence,flexible and portable pressure sensors have shown great application potential in human-computer interaction,personalized medicine and other fields.By comparison with traditional inorganic materials,flexible polymeric materials conformable to the human body are more suitable for the fabrication of wearable pressure sensors.Given the consumption of a huge amount of flexible wearable electronics in near future,it is necessary to turn their attention to biodegradable polymers for the fabrication of flexible pressure sensors toward the development requirement of green and sustainable electronics.In this paper,the structure and properties of silk fibroin(SF)are introduced,and the source and research progress of the piezoelectric properties of SF are systematically discussed.In addition,this paper summarizes the advance in the studies on SF-based capacitive,resistive,triboelectric,and piezoelectric sensors reported in recent years,and focuses on their fabrication methods and applications.Finally,this paper also puts forward the future development trend of high-efficiency fabrication and corresponding application of SF-based piezoelectric sensors.It offers new insights into the design and fabrication of green and biodegradable bioelectronics for in vitro and in vivo sensing applications.
基金supported by the National Key Research and Development Program of China(2022YFD2301100)National Natural Science Foundation of China(32272156)+3 种基金Natural Science Foundation of Fujian Province,China(2022J01160)Central Publicinterest Scientific Institution Basal Research Fund(1630052024003,1630052024020)Chinese Academy of Tropical Agricultural Sciences for Science and Technology Innovation Team of National Tropical Agricultural Science Center(CATASCXTD202402)China Agriculture Research System of MOF and MARA(CARS-17).
文摘Sugarcane is recognized as the fifth largest crop globally,supplying 80%of sugar and 40%of bioenergy production.However,sugarcane genetic research has significantly lagged behind other crops due to its complex genetic background,high ploidy(8-13×),aneuploidy,limited flowering,and a long growth cycle(more than one year).Cross breeding began in 1887 following the discovery that sugarcane seeds could germinate.Both self-and cross-pollination and selection were conducted by sugarcane breeders,but new cultivars were often eliminated due to disease susceptibility.Within the Saccharum genus,different species possess variable numbers of chromosomes.Wild sugarcane species intercrossed with each other,leading to development of the‘Nobilization’breeding strategy,which significantly improved yield,sucrose,fiber content,and disease resistance,and accelerated genetic improvement of cultivars.In recent years,scientific achievements have also been made in sugarcane genome sequencing,molecular marker development,genetic linkage map construction,localization of quantitative trait locus(QTL),and trait-associated gene identification.This review focuses on the progress in sugarcane genetic research,analyzes the technical difficulties faced,presents opportunities and challenges,and provides guidance and references for future sugarcane genetics research and cultivar breeding.Finally,it offers directions for future on sugarcane genetics.
基金supported by grants from the National Natural Science Foundation of China (Nos. 81172950 and 81671739)the Project of Science and Technology Commission of Shanghai (No. 11431920401)the College Students’ Innovation Ability Training Project of Second Military Medical University (No. MS2017040)
文摘Eight new water-soluble amino acid conjugates 6 a-h of chlorin p6 ethers(5 a-d) were synthesized and preliminarily investigated for their in vitro PDT antitumor activity and structure-activity relationship(SAR). The results showed that all compounds exhibited much higher phototoxicity against tumor cells than talaporfin. SAR analysis indicated that PDT antitumor effect enhanced with the increase of carbon chain length of alkoxyl ether bonds at 3~1-position, and L-aspartic acid was superior to L-glutamic acid. In particular, the IC_50 values of most phototoxic compound 6 d were 0.20 mmol/L against A549 cell and0.41υmmol/L against B16-F10 cell, which individually represented 31-and 24-fold increase of antitumor potency compared to talaporfin, suggesting that it was a promising candidate photosensitizer(PS) for PDT applications due to its strong absorption at long wavelength, high phototoxicity, low dark cytotoxicity and good water-solubility.
