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H型高血压合并颈动脉粥样硬化患者血清Hcy含量与炎症因子、斑块稳定性的相关性 被引量:48
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作者 许金鹏 刘洋 +5 位作者 李靖 邸卫英 徐占稳 赵兴洲 宋书江 刘福林 《中国现代医学杂志》 CAS 北大核心 2017年第28期61-65,共5页
目的观察H型高血压合并颈动脉粥样硬化患者血清同型半胱氨酸(Hcy)含量变化,探讨Hcy与炎症因子、斑块稳定性的关系。方法选取2014年5月-2016年5月在该院接受住院治疗的高血压合并颈动脉粥样硬化患者患者90例。根据其血清Hcy含量分为普通... 目的观察H型高血压合并颈动脉粥样硬化患者血清同型半胱氨酸(Hcy)含量变化,探讨Hcy与炎症因子、斑块稳定性的关系。方法选取2014年5月-2016年5月在该院接受住院治疗的高血压合并颈动脉粥样硬化患者患者90例。根据其血清Hcy含量分为普通高血压合并颈动脉粥样硬化组(普通高血压组,Hcy<10μmol/L,n=47)、H型高血压合并颈动脉粥样硬化组(H型高血压组,Hcy≥10μmol/L,n=43),选取同期在该院接受体检的健康人群作为对照组(n=58)。检测各组研究对象的血清Hcy、炎症因子及斑块稳定性指标含量,进一步分析Hcy含量与炎症因子、斑块稳定性的相关性。结果普通高血压组及H型高血压组患者的血清Hcy、炎症因子及斑块稳定性指标含量与对照组比较,差异有统计学意义(P<0.05),其中H型高血压组患者的血清Hcy,炎症因子人类软骨糖蛋白-39(HCGP-39)、肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)、白细胞介素-1β(IL-1β),斑块稳定性指标五聚素3(PTX3)、脂蛋白相关磷脂酶A2(Lp-PLA2)含量高于普通高血压组患者,斑块稳定性指标总胆红素(TBIL)、直接胆红素(DBIL)、间接胆红素(IBIL)含量低于普通高血压组患者。Pearson线性相关分析显示,H型高血压组患者的血清Hcy含量与炎症因子、斑块稳定性指标直接相关。结论血清Hcy含量升高是H型高血压合并颈动脉粥样硬化患者全身炎症反应加剧、斑块稳定性降低的重要影响因素。 展开更多
关键词 H型高血压 颈动脉粥样硬化 同型半胱氨酸 炎症因子 斑块稳定性
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Effects of ozone water irrigation and spraying on physiological characteristics and gene expression of tomato seedlings
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作者 jin-peng xu Yan-Chong Yu +2 位作者 Tao Zhang Qian Ma Hong-Bing Yang 《Horticulture Research》 SCIE 2021年第1期2823-2833,共11页
Tomato seedlings were used as experimental materials and treated with 1.0,2.0,3.0,and 4.0 mg/L ozone water irrigation and 0.2,0.4,0.6,and 0.8mg/L ozone water spray treatments.Indexes including the malondialdehyde(MDA)... Tomato seedlings were used as experimental materials and treated with 1.0,2.0,3.0,and 4.0 mg/L ozone water irrigation and 0.2,0.4,0.6,and 0.8mg/L ozone water spray treatments.Indexes including the malondialdehyde(MDA)content,superoxide dismutase(SOD),peroxidase(POD)and catalase(CAT),activities,soil and plant analysis development(SPAD)value,and nitrogen content of leaves were measured.Furthermore,the expression of antioxidant enzyme,chlorophyll synthesis and nitrogen absorption genes was analyzed after optimal ozone water treatment.The results showed that the activities of antioxidant enzymes in tomato leaves were significantly increased,and the MDA content in tomato leaves was significantly reduced by ozone water irrigation and spray treatment,which indicated that ozone water treatment can significantly improve the stress tolerance of tomato seedlings.Ozone water irrigation and spraying could also significantly increase the leaf SPAD value and nitrogen content of tomato seedlings,and the optimal concentrations of ozone water irrigation and spraying were 3.0mg/L and 0.6 mg/L,respectively.The effect of ozone water irrigation on improving the physiological characteristics of tomato seedlings was better than that of spraying.After treatment with the optimal concentration of ozone water,the relative expression of antioxidant enzyme,chlorophyll synthesis,and nitrogen absorption genes was significantly increased,and the maximum expression level was reached at 12h.In addition,ozone water irrigation could promote the expression of genes more than ozone water spraying,which was consistent with the improvements in the physiological characteristics of the tomato seedlings. 展开更多
关键词 SEEDLINGS OZONE soil
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18F-FDG PET/CT in vivo assessment of correlation between vascular calcification and inflammation
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作者 Lin Su Guo-Qiang Wang +5 位作者 Li-Mei Zhang Song-Hong Wu Shu-Heng Li Na Li YanZhang jin-peng xu 《Journal of Hainan Medical University》 2020年第8期25-28,共4页
Objective:To explore the relationship between calcification of human vascular system and local inflammation using PET/CT.Methods:Patients who were treated with concurrent PET/CT in our hospital were collected continuo... Objective:To explore the relationship between calcification of human vascular system and local inflammation using PET/CT.Methods:Patients who were treated with concurrent PET/CT in our hospital were collected continuously,and their arterial image data were analyzed in parallel with standardized uptake values.(SUV)and corresponding slice calcification score(CS)measurement.SUV values were collected and measured for slices with CS greater than 100.Patients were grouped according to CS,and the correlation analysis between SUV values and CS in each group was performed.Results:Overall CS and SUVmax(r=0.62,P<0.05)and SUVmean(r=0.59,P<0.05)were positively correlated,among which CS and SUV values were in the SUVmax(r=0.72,P<0.05),SUVmean(r=0.59,P<0.05),SUVmax of CS 200-299 group(r=0.71,P<0.05),SUVmean(r=0.80,P<0.05),SUVmax of CS 300-399 group(r=0.47,P<0.05),SUVmean(r=0.53,P<0.05)were positively correlated,SUVmax(r=-0.17,P>0.05),SUVmean(r=-0.07,P>0.05)were negatively correlated in CS 400-499 group,CS There was no significant correlation between SUVmax(r=0.22,P>0.05)and SUVmean(r=0.18,P>0.05)in the 500 group.Conclusion:There is a certain correlation between the local vascular calcification area and the corresponding local inflammatory response in the calcification progress PET/CT has the potential to monitor early calcification. 展开更多
关键词 Positron emission computed tomography/computed tomography CALCIFICATION INFLAMMATION
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