Moirésuperlattices in twisted two-dimensional materials have emerged as ideal platforms for engineering quantum phenomena,which are highly sensitive to twist angles,including both the global value and the spatial...Moirésuperlattices in twisted two-dimensional materials have emerged as ideal platforms for engineering quantum phenomena,which are highly sensitive to twist angles,including both the global value and the spatial inhomogeneity.However,only a few methods provide spatial-resolved information for characterizing local twist angle distribution.展开更多
In the past several years,remarkable achievements have been made in the field of object detection.Although performance is generally improving,the accuracy of small object detection remains low compared with that of la...In the past several years,remarkable achievements have been made in the field of object detection.Although performance is generally improving,the accuracy of small object detection remains low compared with that of large object detection.In addition,localization misalignment issues are common for small objects,as seen in GoogLeNets and residual networks(ResNets).To address this problem,we propose an improved region-based fully convolutional network(R-FCN).The presented technique improves detection accuracy and eliminates localization misalignment by replacing positionsensitive region of interest(PS-RoI)pooling with position-sensitive precise region of interest(PS-Pr-RoI)pooling,which avoids coordinate quantization and directly calculates two-order integrals for position-sensitive score maps,thus preventing a loss of spatial precision.A validation experiment was conducted in which the Microsoft common objects in context(MS COCO)training dataset was oversampled.Results showed an accuracy improvement of 3.7%for object detection tasks and an increase of 6.0%for small objects.展开更多
[Objectives]To treat pig farm wastewater and solve the problem of pollution caused by it to surface water or groundwater.[Methods]Fe and Zn/biochar(AC)was prepared by dipping method using pig manure-derived biochar as...[Objectives]To treat pig farm wastewater and solve the problem of pollution caused by it to surface water or groundwater.[Methods]Fe and Zn/biochar(AC)was prepared by dipping method using pig manure-derived biochar as carrier.The preparation conditions were investigated,and the screened metal-loaded biochar was characterized.Pig farm waste water was treated with metal-loaded biochar-H2O2 catalytic oxidation method.[Results]At the COD concentration of 2904 mg/L,0.02 g Zn/AC and 0.005 mL H2O2 showed the highest COD removal rate(qe)from pig breeding wastewater under conditions of reaction time of 8 h,pH value of 7 and temperature of 55℃,reaching 70.98%.[Conclusions]Fe or Zn-loaded biochar made from pig manure-derived activated carbon has a certain catalytic capacity for the actual oxidation treatment of pig farm wastewater.The activity of Zn/AC was higher,and its COD removal rate from pig farm wastewater was also higher.展开更多
Based on Recursive Radial Basis Function(RRBF)neural network,the Reduced Order Model(ROM)of compressor cascade was established to meet the urgent demand of highly efficient prediction of unsteady aerodynamics performa...Based on Recursive Radial Basis Function(RRBF)neural network,the Reduced Order Model(ROM)of compressor cascade was established to meet the urgent demand of highly efficient prediction of unsteady aerodynamics performance of turbomachinery.One novel ROM called ASA-RRBF model based on Adaptive Simulated Annealing(ASA)algorithm was developed to enhance the generalization ability of the unsteady ROM.The ROM was verified by predicting the unsteady aerodynamics performance of a highly-loaded compressor cascade.The results show that the RRBF model has higher accuracy in identification of the dimensionless total pressure and dimensionless static pressure of compressor cascade under nonlinear and unsteady conditions,and the model behaves higher stability and computational efficiency.However,for the strong nonlinear characteristics of aerodynamic parameters,the RRBF model presents lower accuracy.Additionally,the RRBF model predicts with a large error in the identification of aerodynamic parameters under linear and unsteady conditions.For ASA-RRBF,by introducing a small-amplitude and highfrequency sinusoidal signal as validation sample,the width of the basis function of the RRBF model is optimized to improve the generalization ability of the ROM under linear unsteady conditions.Besides,this model improves the predicting accuracy of dimensionless static pressure which has strong nonlinear characteristics.The ASA-RRBF model has higher prediction accuracy than RRBF model without significantly increasing the total time consumption.This novel model can predict the linear hysteresis of dimensionless static pressure happened in the harmonic condition,but it cannot accurately predict the beat frequency of dimensionless total pressure.展开更多
Exosomes are highly important in clinical diagnosis due to their high homology with their parental cells.However,conventional exosome detection methods still face the challenges of expensive equipment,low sensitivity,...Exosomes are highly important in clinical diagnosis due to their high homology with their parental cells.However,conventional exosome detection methods still face the challenges of expensive equipment,low sensitivity,and complex procedures.Field effect transistors(FETs)are not only the most essential electronic component in the modern microelectronics industry but also show great potential for biomolecule detection owing to the advantages of rapid response,high sensitivity,and label-free detection.In this study,we proposed a Si nanowire field-effect transistor(Si-NW Bio-FET)device chemically modified with specific antibodies for the electrical and label-free detection of exosomes.The Si-NW FETs were fabricated by standard microelectronic processes with 45 nm width nanowires and packaged in a polydimethylsiloxane(PDMS)microfluidic channel.The nanowires were further modified with the specific CD63 antibody to form a Si-NW Bio-FET.The use of the developed Si-NW Bio-FET for the electrical and labelfree detection of exosomes was successfully demonstrated with a limit of detection(LOD)of 2159 particles/mL.In contrast to other technologies,in this study,Si-NW Bio-FET provides a unique strategy for directly quantifying and realtime detecting exosomes without labeling,indicating its potential as a tool for the early diagnosis of cancer.展开更多
Contact electrification occurs in many granular material systems due to particle-particle and particle-wall contacts.In this paper,we used a simple device to characterize the electrification of different spheres in a ...Contact electrification occurs in many granular material systems due to particle-particle and particle-wall contacts.In this paper,we used a simple device to characterize the electrification of different spheres in a rotating spherical container.The charge of the spheres was quantified by a Faraday cup after rotating for various time and the disperse behaviors of charged spheres were recorded by a camera.The effects of the rotational time,sphere size,rotational speed,sphere material,and relative humidity on the equilibrium charge and triboelectric coefficient were analyzed.The results show that the equilibrium surface charge density is independent of the sphere size and the rotating speed,whereas the larger rotating speed enhances the triboelectric coefficient.It is also shown that charge relaxation constants are two orders of magnitude lower than the charge generation constants for all spheres at a low relative humidity.The increase of water molecules in the air was found to result in the decline of charge generation constant and the rise of charge relaxation constant,which together cause the decrease of the equilibrium surface charge density.展开更多
We study,in the framework of open quantum systems,the entanglement generation of two atoms in between two parallel mirrors in a thermal bath of quantum scalar fields.We find that the presence of mirrors plays an impor...We study,in the framework of open quantum systems,the entanglement generation of two atoms in between two parallel mirrors in a thermal bath of quantum scalar fields.We find that the presence of mirrors plays an important role in entanglement generation and protection.The entanglement dynamics is crucially dependent on the geometric configurations of the two-atom system with respect to the mirrors,and the ranges of temperature and interatomic separation within which entanglement can be generated are significantly changed compared with those in a free space.In particular,when the atomic transition wavelength is larger than twice the distance between the two mirrors,the atoms behave as if they were isolated from the environment and the entanglement can persist in the steady state if the atoms are initially entangled and no entanglement can be created if they are initially separable,no matter how the atoms are placed with respect to the mirrors and to each other.This is in sharp contrast to the fact that in a free space,steady-state entanglement is possible only when the two atoms are placed extremely close to each other,while in the presence of one mirror,it is possible when the two atoms placed extremely close to the mirror.展开更多
As a highly toxic heavy metal,Cr(VI)reduction by developing high-efficiency photocatalysts is of great significance.Herein,we firstly design few-layer Ti_(3)C_(2) MXene(FTM)by the hand-operated shaking,show-ing dual a...As a highly toxic heavy metal,Cr(VI)reduction by developing high-efficiency photocatalysts is of great significance.Herein,we firstly design few-layer Ti_(3)C_(2) MXene(FTM)by the hand-operated shaking,show-ing dual advantages of structural stability and more exposed reactive sites.Then,a refluxed process is performed to fabricate FTM/CaIn_(2)S_(4)(FTC) composites,where 2D CaIn_(2)S_(4)(CIS) nanoplates are closely con-nected with 2D FTM to form Schottky junction.The optimal 1-FTC with the FTM/CIS mass ratio of 1 wt.%exhibits the highest activity toward photocatalytic Cr(VI)reduction under visible light.It is well eluci-dated that the broadened light absorption range and promoted charge carrier separation rate induced by the introduction of FTM are responsible for improving photocatalytic activity of CIS.During Cr(VI)photoreduction,1-FTC possesses excellent photo-stability and reusability.The effects of catalyst mass,co-existing ions,water sources and pH values on the Cr(VI)photoreduction efficiency are investigated.Pho-togenerated•O_(2)^(−)and e−are the main radical species accounting for Cr(VI)photoreduction over 1-FTC.The photocatalytic mechanism along with Cr(VI)removal pathway is exploited.This work may provide some insights into constructing FTM-based Schottky junctions for the efficient water purification.展开更多
The correlation of surface impurity states with the antiferromagnetic ground states is crucial for understanding the formation of the topological surface state in the antiferromagnetic topological insulators MnBi_(2)T...The correlation of surface impurity states with the antiferromagnetic ground states is crucial for understanding the formation of the topological surface state in the antiferromagnetic topological insulators MnBi_(2)Te_(4).By using low-temperature scanning tunneling microscopy and spectroscopy,we observed a localized bound state around the Mn-Bi antisite defect at the Teterminated surface of the antiferromagnetic topological insulator MnBi_(2)Te_(4).When applying a magnetic field perpendicular to the surface(Bz)from–1.5 to 3.0 T,the bound state shifts linearly to a lower energy with increasing Bz,which is attributed to the Zeeman effect.Remarkably,when applying a large range of Bz from–8.0 to 8.0 T,the magnetic field induced reorientation of surface magnetic moments results in an abrupt jump in the local density of states(LDOS),which is characterized by LDOSchange-ratio■quantitatively.Interestingly,two asymmetric critical field,–2.0 and 4.0 T determined by the two peaks in■are observed,which is consistent with simulated results according to a Mills-model,describing a surface spin flop transition(SSF).Our results provide a new flatform for studying the interplay between magnetic order and topological phases in magnetic topological materials.展开更多
Honeybees and bumblebees play a crucial role as essential pollinators.The special gut microbiome of social bees is a key factor in determining the overall fitness and health of the host.Although bees harbor relatively...Honeybees and bumblebees play a crucial role as essential pollinators.The special gut microbiome of social bees is a key factor in determining the overall fitness and health of the host.Although bees harbor relatively simple microbial communities at the genus level,recent studies have unveiled significant genetic divergence and variations in gene content within each bacterial genus.However,a comprehensive and refined genomics-based taxonomic database specific to social bee gut microbiomes remains lacking.Here,we first provided an overview of the current knowledge on the distribution and function of social bee gut bacteria,as well as the factors that influence the gut population dynamics.We then consolidated all available genomes of the gut bacteria of social bees and refined the species-level taxonomy,by constructing a maximum-likelihood core genome phylogeny and calculating genome-wide pairwise average nucleotide identity.On the basis of the refined species taxonomy,we constructed a curated genomic reference database,named the bee gut microbe genome sequence database(BGM-GDb).To evaluate the species-profiling performance of the curated BGM-GDb,we retrieved a series of bee gut metagenomic data and inferred the species-level composition using metagenomic intra-species diversity analysis system(MIDAS),and then compared the results with those obtained from a prebuilt MIDAS database.We found that compared with the default database,the BGM-GDb excelled in aligned read counts and bacterial richness.Overall,this high-resolution and precise genomic reference database will facilitate research in understanding the gut community structure of social bees.展开更多
Dear Editor,SARS-CoV-2 is the virus that caused the COVID-19 pandemic,leading to more than 774 million cases and 7,037,007 deaths by March 2024(World Health Organization,http://covid19.who.int/).Despite effective trea...Dear Editor,SARS-CoV-2 is the virus that caused the COVID-19 pandemic,leading to more than 774 million cases and 7,037,007 deaths by March 2024(World Health Organization,http://covid19.who.int/).Despite effective treatments,15%-20%of patients experience long-term symptoms,such as breathlessness,fatigue,depression,and cognitive impairment,which are often linked to an excessive immune response[1].All variants of the virus(α,,,Omicron,and BA.1),which can potentially access the brain via the olfactory mucosa,have been found in the brains of Syrian hamsters,triggering inflammation and demonstrating axonal travel[2].展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.61888102 and 12374199)the National Key Research&Development Projects of China(Grant Nos.2022YFA1204100,2019YFA0308501,and 2021YFA1401300)+1 种基金the Chinese Academy of Sciences(Grant No.XDB33030100)the Innovation Program of Quantum Science and Technology(Grant No.2021ZD0302700)。
文摘Moirésuperlattices in twisted two-dimensional materials have emerged as ideal platforms for engineering quantum phenomena,which are highly sensitive to twist angles,including both the global value and the spatial inhomogeneity.However,only a few methods provide spatial-resolved information for characterizing local twist angle distribution.
基金This project was supported by the National Natural Science Foundation of China under grant U1836208the Hunan Provincial Natural Science Foundations of China under Grant 2020JJ4626+2 种基金the Scientific Research Fund of Hunan Provincial Education Department of China under Grant 19B004the“Double First-class”International Cooperation and Development Scientific Research Project of Changsha University of Science and Technology under Grant 2018IC25the Young Teacher Growth Plan Project of Changsha University of Science and Technology under Grant 2019QJCZ076.
文摘In the past several years,remarkable achievements have been made in the field of object detection.Although performance is generally improving,the accuracy of small object detection remains low compared with that of large object detection.In addition,localization misalignment issues are common for small objects,as seen in GoogLeNets and residual networks(ResNets).To address this problem,we propose an improved region-based fully convolutional network(R-FCN).The presented technique improves detection accuracy and eliminates localization misalignment by replacing positionsensitive region of interest(PS-RoI)pooling with position-sensitive precise region of interest(PS-Pr-RoI)pooling,which avoids coordinate quantization and directly calculates two-order integrals for position-sensitive score maps,thus preventing a loss of spatial precision.A validation experiment was conducted in which the Microsoft common objects in context(MS COCO)training dataset was oversampled.Results showed an accuracy improvement of 3.7%for object detection tasks and an increase of 6.0%for small objects.
基金Scientific and Technological Innovation Project of Jingjiang City,Jiangsu Province(HDCXJ6001).
文摘[Objectives]To treat pig farm wastewater and solve the problem of pollution caused by it to surface water or groundwater.[Methods]Fe and Zn/biochar(AC)was prepared by dipping method using pig manure-derived biochar as carrier.The preparation conditions were investigated,and the screened metal-loaded biochar was characterized.Pig farm waste water was treated with metal-loaded biochar-H2O2 catalytic oxidation method.[Results]At the COD concentration of 2904 mg/L,0.02 g Zn/AC and 0.005 mL H2O2 showed the highest COD removal rate(qe)from pig breeding wastewater under conditions of reaction time of 8 h,pH value of 7 and temperature of 55℃,reaching 70.98%.[Conclusions]Fe or Zn-loaded biochar made from pig manure-derived activated carbon has a certain catalytic capacity for the actual oxidation treatment of pig farm wastewater.The activity of Zn/AC was higher,and its COD removal rate from pig farm wastewater was also higher.
基金co-National Science and Technology Major Project(No.2017-II-0009-0023)Innovation Guidance Support Project for Taicang Top Research Institutes(No.TC2019DYDS09)。
文摘Based on Recursive Radial Basis Function(RRBF)neural network,the Reduced Order Model(ROM)of compressor cascade was established to meet the urgent demand of highly efficient prediction of unsteady aerodynamics performance of turbomachinery.One novel ROM called ASA-RRBF model based on Adaptive Simulated Annealing(ASA)algorithm was developed to enhance the generalization ability of the unsteady ROM.The ROM was verified by predicting the unsteady aerodynamics performance of a highly-loaded compressor cascade.The results show that the RRBF model has higher accuracy in identification of the dimensionless total pressure and dimensionless static pressure of compressor cascade under nonlinear and unsteady conditions,and the model behaves higher stability and computational efficiency.However,for the strong nonlinear characteristics of aerodynamic parameters,the RRBF model presents lower accuracy.Additionally,the RRBF model predicts with a large error in the identification of aerodynamic parameters under linear and unsteady conditions.For ASA-RRBF,by introducing a small-amplitude and highfrequency sinusoidal signal as validation sample,the width of the basis function of the RRBF model is optimized to improve the generalization ability of the ROM under linear unsteady conditions.Besides,this model improves the predicting accuracy of dimensionless static pressure which has strong nonlinear characteristics.The ASA-RRBF model has higher prediction accuracy than RRBF model without significantly increasing the total time consumption.This novel model can predict the linear hysteresis of dimensionless static pressure happened in the harmonic condition,but it cannot accurately predict the beat frequency of dimensionless total pressure.
基金support from the National Key Research and Development Program of China(2020YFC2004503)Beijing Nova Program(Z2011006820083,Z2011006820084)Beijing Municipal Natural Science Foundation(No.4192062).
文摘Exosomes are highly important in clinical diagnosis due to their high homology with their parental cells.However,conventional exosome detection methods still face the challenges of expensive equipment,low sensitivity,and complex procedures.Field effect transistors(FETs)are not only the most essential electronic component in the modern microelectronics industry but also show great potential for biomolecule detection owing to the advantages of rapid response,high sensitivity,and label-free detection.In this study,we proposed a Si nanowire field-effect transistor(Si-NW Bio-FET)device chemically modified with specific antibodies for the electrical and label-free detection of exosomes.The Si-NW FETs were fabricated by standard microelectronic processes with 45 nm width nanowires and packaged in a polydimethylsiloxane(PDMS)microfluidic channel.The nanowires were further modified with the specific CD63 antibody to form a Si-NW Bio-FET.The use of the developed Si-NW Bio-FET for the electrical and labelfree detection of exosomes was successfully demonstrated with a limit of detection(LOD)of 2159 particles/mL.In contrast to other technologies,in this study,Si-NW Bio-FET provides a unique strategy for directly quantifying and realtime detecting exosomes without labeling,indicating its potential as a tool for the early diagnosis of cancer.
基金This work was funded by the National Natural Science Foundation of China(51976039)the China Scholarship Council(201906090034)the Scientific Research Foundation of Graduate School of Southeast University(YBPY1905).
文摘Contact electrification occurs in many granular material systems due to particle-particle and particle-wall contacts.In this paper,we used a simple device to characterize the electrification of different spheres in a rotating spherical container.The charge of the spheres was quantified by a Faraday cup after rotating for various time and the disperse behaviors of charged spheres were recorded by a camera.The effects of the rotational time,sphere size,rotational speed,sphere material,and relative humidity on the equilibrium charge and triboelectric coefficient were analyzed.The results show that the equilibrium surface charge density is independent of the sphere size and the rotating speed,whereas the larger rotating speed enhances the triboelectric coefficient.It is also shown that charge relaxation constants are two orders of magnitude lower than the charge generation constants for all spheres at a low relative humidity.The increase of water molecules in the air was found to result in the decline of charge generation constant and the rise of charge relaxation constant,which together cause the decrease of the equilibrium surface charge density.
基金supported in part by the NSFC under Grants No.11805063,No.11690034,and No.12075084the Hunan Provincial Natural Science Foundation of China under Grant No.2020JJ3026。
文摘We study,in the framework of open quantum systems,the entanglement generation of two atoms in between two parallel mirrors in a thermal bath of quantum scalar fields.We find that the presence of mirrors plays an important role in entanglement generation and protection.The entanglement dynamics is crucially dependent on the geometric configurations of the two-atom system with respect to the mirrors,and the ranges of temperature and interatomic separation within which entanglement can be generated are significantly changed compared with those in a free space.In particular,when the atomic transition wavelength is larger than twice the distance between the two mirrors,the atoms behave as if they were isolated from the environment and the entanglement can persist in the steady state if the atoms are initially entangled and no entanglement can be created if they are initially separable,no matter how the atoms are placed with respect to the mirrors and to each other.This is in sharp contrast to the fact that in a free space,steady-state entanglement is possible only when the two atoms are placed extremely close to each other,while in the presence of one mirror,it is possible when the two atoms placed extremely close to the mirror.
基金This work was financially supported by the National Natural Science Foundation of China(Nos.51902282 and 12274361)the Qinglan Project of Jiangsu of China,the Natural Science Founda-tion of Jiangsu Province(No.BK20211361)the College Natural Science Research Project of Jiangsu Province(No.20KJA430004).
文摘As a highly toxic heavy metal,Cr(VI)reduction by developing high-efficiency photocatalysts is of great significance.Herein,we firstly design few-layer Ti_(3)C_(2) MXene(FTM)by the hand-operated shaking,show-ing dual advantages of structural stability and more exposed reactive sites.Then,a refluxed process is performed to fabricate FTM/CaIn_(2)S_(4)(FTC) composites,where 2D CaIn_(2)S_(4)(CIS) nanoplates are closely con-nected with 2D FTM to form Schottky junction.The optimal 1-FTC with the FTM/CIS mass ratio of 1 wt.%exhibits the highest activity toward photocatalytic Cr(VI)reduction under visible light.It is well eluci-dated that the broadened light absorption range and promoted charge carrier separation rate induced by the introduction of FTM are responsible for improving photocatalytic activity of CIS.During Cr(VI)photoreduction,1-FTC possesses excellent photo-stability and reusability.The effects of catalyst mass,co-existing ions,water sources and pH values on the Cr(VI)photoreduction efficiency are investigated.Pho-togenerated•O_(2)^(−)and e−are the main radical species accounting for Cr(VI)photoreduction over 1-FTC.The photocatalytic mechanism along with Cr(VI)removal pathway is exploited.This work may provide some insights into constructing FTM-based Schottky junctions for the efficient water purification.
基金This work is supported by the National Natural Science Foundation of China(Nos.61888102 and 52022105)National Key Research and Development Projects of China(Nos.2018YFA0305800 and 2019YFA0308500)+2 种基金the Strategic Priority Research Program of Chinese Academy of Sciences(Nos.XDB30000000 and XDB28000000)CAS Project for Young Scientists in Basic Research(No.YSBR-003)the University of Chinese Academy of Sciences.
文摘The correlation of surface impurity states with the antiferromagnetic ground states is crucial for understanding the formation of the topological surface state in the antiferromagnetic topological insulators MnBi_(2)Te_(4).By using low-temperature scanning tunneling microscopy and spectroscopy,we observed a localized bound state around the Mn-Bi antisite defect at the Teterminated surface of the antiferromagnetic topological insulator MnBi_(2)Te_(4).When applying a magnetic field perpendicular to the surface(Bz)from–1.5 to 3.0 T,the bound state shifts linearly to a lower energy with increasing Bz,which is attributed to the Zeeman effect.Remarkably,when applying a large range of Bz from–8.0 to 8.0 T,the magnetic field induced reorientation of surface magnetic moments results in an abrupt jump in the local density of states(LDOS),which is characterized by LDOSchange-ratio■quantitatively.Interestingly,two asymmetric critical field,–2.0 and 4.0 T determined by the two peaks in■are observed,which is consistent with simulated results according to a Mills-model,describing a surface spin flop transition(SSF).Our results provide a new flatform for studying the interplay between magnetic order and topological phases in magnetic topological materials.
基金supported by grants from the National Natural Science Foundation of China(32370550 and 32000346)to Xue Zhangthe program from the Sanya Institute of China Agricultural University(SYND-2021-30)by 2115 Talent Development Program of China Agricultural University grants to Xin Zhou。
文摘Honeybees and bumblebees play a crucial role as essential pollinators.The special gut microbiome of social bees is a key factor in determining the overall fitness and health of the host.Although bees harbor relatively simple microbial communities at the genus level,recent studies have unveiled significant genetic divergence and variations in gene content within each bacterial genus.However,a comprehensive and refined genomics-based taxonomic database specific to social bee gut microbiomes remains lacking.Here,we first provided an overview of the current knowledge on the distribution and function of social bee gut bacteria,as well as the factors that influence the gut population dynamics.We then consolidated all available genomes of the gut bacteria of social bees and refined the species-level taxonomy,by constructing a maximum-likelihood core genome phylogeny and calculating genome-wide pairwise average nucleotide identity.On the basis of the refined species taxonomy,we constructed a curated genomic reference database,named the bee gut microbe genome sequence database(BGM-GDb).To evaluate the species-profiling performance of the curated BGM-GDb,we retrieved a series of bee gut metagenomic data and inferred the species-level composition using metagenomic intra-species diversity analysis system(MIDAS),and then compared the results with those obtained from a prebuilt MIDAS database.We found that compared with the default database,the BGM-GDb excelled in aligned read counts and bacterial richness.Overall,this high-resolution and precise genomic reference database will facilitate research in understanding the gut community structure of social bees.
基金sponsored by the National Key Research&Development Program of China(2022YFC3602700 and 2022YFC3602702)the Science and Technology Innovation 2030-Brain Science and Brain-Inspired Intelligence Project(2021ZD0201301)+1 种基金the National Natural Science Foundation of China(32170688 and 82172109)Shanghai Municipal Science and Technology Major Project(2018SHZDZX01),and ZJLab.
文摘Dear Editor,SARS-CoV-2 is the virus that caused the COVID-19 pandemic,leading to more than 774 million cases and 7,037,007 deaths by March 2024(World Health Organization,http://covid19.who.int/).Despite effective treatments,15%-20%of patients experience long-term symptoms,such as breathlessness,fatigue,depression,and cognitive impairment,which are often linked to an excessive immune response[1].All variants of the virus(α,,,Omicron,and BA.1),which can potentially access the brain via the olfactory mucosa,have been found in the brains of Syrian hamsters,triggering inflammation and demonstrating axonal travel[2].