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金花清感颗粒治疗成人新型冠状病毒肺炎患者的多中心前瞻性队列研究 被引量:13
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作者 张佳莹 李丽 +3 位作者 汪晓军 李秀惠 金荣华 冯英梅 《北京医学》 CAS 2021年第9期866-870,共5页
目的探讨金花清感颗粒应用于成人新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)患者的有效性和安全性。方法选取2020年1月27日至3月23日北京地区15家医院收治的成人COVID-19患者245例,建立前瞻性研究队列,服用金花清感颗粒≥3 ... 目的探讨金花清感颗粒应用于成人新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)患者的有效性和安全性。方法选取2020年1月27日至3月23日北京地区15家医院收治的成人COVID-19患者245例,建立前瞻性研究队列,服用金花清感颗粒≥3 d的队列为观察组,常规治疗的队列为对照组。收集所有患者的临床资料,比较两组各指标的差异。结果观察组71例(29.0%),对照组174例(71.0%)。治疗后观察组咳嗽好转率和倦怠乏力好转率,显著优于对照组[65.9%比38.4%,87.0%比54.4%],差异有统计学意义(P<0.05)。观察组新型冠状病毒核酸平均转阴时间显著低于对照组[(13.85±7.96)d比(17.90±8.89)d],差异有统计学意义(P<0.05)。Kaplan-Meier曲线和log-rank检验提示观察组有较低的新冠病毒核酸阳性率(χ^(2)=10.337,P<0.05)。观察组与对照组的住院时间和病死率比较,差异无统计学意义(P>0.05)。两组均未出现明显的不良事件。结论金花清感颗粒治疗COVID-19不改变病死率和住院时间,但可以缩短患者咳嗽、倦怠乏力等症状的持续时间,并可以缩短新型冠状病毒核酸转阴时间。 展开更多
关键词 新型冠状病毒 金花清感颗粒 疗效 队列研究
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BLIND CHANNEL ESTIMATION IN DELAY DIVERSITY FOR FREQUENCY SELECTIVE CHANNELS
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作者 ZhaoZheng jiaying YinQinye 《Journal of Electronics(China)》 2003年第5期326-336,共11页
Delay diversity is an effective transmit diversity technique to combat adverse effects of fading. Thus far, previous work in delay diversity assumed that perfect estimates of current channel fading conditions are ava... Delay diversity is an effective transmit diversity technique to combat adverse effects of fading. Thus far, previous work in delay diversity assumed that perfect estimates of current channel fading conditions are available at the receiver and training symbols are required to estimate the channel from the transmitter to the receiver. However, increasing the number of the antennas increases the required training interval and reduces the available time with in whichdata may be transmitted. Learning the channel coefficients becomes increasingly difficult for the frequency selective channels. In this paper, with the subspace method and the delay character of delay diversity, a channel estimation method is proposed, which does not use training symbols. It addresses the transmit diversity for a frequency selective channel from a single carrier perspective in the form of a simple equivalent flat fading model. Monte Carlo simulations give the performance of channel estimation and the performance comparison of our channel-estimation-based detector with decision feedback equalization, which uses the perfect channel information. 展开更多
关键词 Delay diversity Subspace method Blind channel estimation Frequency selective channels Array signal processing
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