John Makeham, a leading intellectual historian of modem China, has authored and edited several important works about the transformation of knowledge in modem Chinese history resulting from fierce interactions between ...John Makeham, a leading intellectual historian of modem China, has authored and edited several important works about the transformation of knowledge in modem Chinese history resulting from fierce interactions between China and the West as well as between modem and traditional China. His latest volume, Transforming Consciousness, is an example of the latter. In this anthology, Makeham assembles a group of specialists from Australia.展开更多
文摘目的探讨老年患者的衰弱状态对顺式阿曲库铵的起效时间和作用时间的影响。方法选择2022年6月—2024年4月本院收治的择期行腹腔镜下胃癌根治手术的老年患者(年龄大于65岁)作为研究对象,术前访视时根据改良衰弱指数(modified Frailty Index mFI-11)评估量表对老年患者进行改良衰弱指数评估并记录。随机选取没有数据缺失项的患者87例纳入本研究中,采集数据后根据mFI-11指数分为两组:mFI<0.27分为C组(非衰弱组),mFI≥0.27分为D组(衰弱组)。两组患者均行气管插管全麻(麻醉诱导、维持方案一致),入室后均进行肌松监测,分别记录患者入室镇静镇痛药物推注之后加速度肌松监测仪测得的T1及TOfr基础值(TOFrc),顺式阿曲库胺(0.15 mg/kg)推注后TOFr为0的时间(t0)、术中第1次TOFr为0.25的时间(t1)等数据,并进行比较分析。结果两组患者在罹患高血压、糖尿病、周围血管疾病、感觉障碍、生活依赖程度、短暂性脑缺血发作或脑血管意外病史以及脑血管事件伴神经功能受损方面比较,差异均具有统计学意义(P<0.05);两组间t0时间比较,D组较C组t0时间明显缩短,差异具有统计学意义(P<0.01);两组间t1时间比较,D组较C组t1时间明显延长,差异具有统计学意义(P<0.01);两组间T1及TOFrc没有统计学意义(P>0.05)。结论改良衰弱指数评估为衰弱状态的患者与非衰弱状态患者相比,肌松监测下显示顺式阿曲库胺推注后,达到TOFr=0的时间更短、术中恢复到TOFr=0.25的时间更长,即随着衰弱程度的增加,顺式阿曲库胺起效时间更短,肌松开始恢复的时间则需要更长。
文摘John Makeham, a leading intellectual historian of modem China, has authored and edited several important works about the transformation of knowledge in modem Chinese history resulting from fierce interactions between China and the West as well as between modem and traditional China. His latest volume, Transforming Consciousness, is an example of the latter. In this anthology, Makeham assembles a group of specialists from Australia.
