Asparagus setaceus is a popular ornamental plant cultivated in tropical and subtropical regions globally.Here,we constructed a chromosome-scale reference genome of A.setaceus to facilitate the investigation of its gen...Asparagus setaceus is a popular ornamental plant cultivated in tropical and subtropical regions globally.Here,we constructed a chromosome-scale reference genome of A.setaceus to facilitate the investigation of its genome characteristics and evolution.Using a combination of Nanopore long reads,Illumina short reads,10×Genomics linked reads,and Hi-C data,we generated a high-quality genome assembly of A.setaceus covering 710.15 Mb,accounting for 98.63%of the estimated genome size.A total of 96.85%of the sequences were anchored to ten superscaffolds corresponding to the ten chromosomes.The genome of A.setaceus was predicted to contain 28,410 genes,25,649(90.28%)of which were functionally annotated.A total of 65.59%of the genome was occupied by repetitive sequences,among which long terminal repeats were predominant(42.51%of the whole genome).Evolutionary analysis revealed an estimated divergence time of A.setaceus from its close relative A.officinalis of~9.66 million years ago,and A.setaceus underwent two rounds of whole-genome duplication.In addition,762 specific gene families,96 positively selected genes,and 76 resistance(R)genes were detected and functionally predicted in A.setaceus.These findings provide new knowledge about the characteristics and evolution of the A.setaceus genome,and will facilitate comparative genetic and genomic research on the genus Asparagus.展开更多
Sediment layers containing contaminants play a significant role in environmental hydrodynamics. Experiments were conducted in order to characterize the relative roles of resuspended particles and pore water under diff...Sediment layers containing contaminants play a significant role in environmental hydrodynamics. Experiments were conducted in order to characterize the relative roles of resuspended particles and pore water under different flow and sediment conditions. A conservative tracer （NaC1） and a reactive tracer （phosphate） were used as contaminants in the bottom sediment in a laboratory flume. The mixing between the overlying water and pore water occurred over a short time while the desorption of contaminants from fine-grained resuspended particles lasted a relatively long time. The effects of resuspended particles and pore water on the variations of release flux and concentration of contaminants in water with time under different hydrodynamic conditions were quantified. The results show that pore water dominated the initial release flux, which could be several orders of magnitude greater than the flux due to molecular diffusion. Flux contribution of desorption from sediment particles in the latter release could be equal to what was seen from pore water in the initial stage.展开更多
We experimentally investigate the effect of the hopper angle on the flow rate of grains discharged from a twodimensional horizontal hopper on a conveyor belt.The flow rate grows with the hopper angle,and finally reach...We experimentally investigate the effect of the hopper angle on the flow rate of grains discharged from a twodimensional horizontal hopper on a conveyor belt.The flow rate grows with the hopper angle,and finally reaches a plateau.The curve feature appears to be similar for different orifice widths and conveyor belt-driven velocities.On the basis of an empirical law of flow rate for a flat-bottom hopper,we propose a modified equation to describe the relation between the flow rate and hopper angle,which is in a good agreement with the experimental results.展开更多
Objectives To assess the regional diastolic function in patients with hypertrophic cardiomyopathy （HCM） by using single-beat, real-time, three-dimensional echocardiography （RT-3DE）. Methods Sixty-five patients wit...Objectives To assess the regional diastolic function in patients with hypertrophic cardiomyopathy （HCM） by using single-beat, real-time, three-dimensional echocardiography （RT-3DE）. Methods Sixty-five patients with HCM in sinus rhythm together with fifty age- and gender-matched normal controls were studied by two dimensional echocardiography （2DE） and RT-3DE. The parameters analyzed by RT-3DE included： left ventrieular （LV） volumes, left ventricular ejection fraction （LVEF）, end diastolic sphericity index （EDSI）, diastolic dyssynchrony index （DDI）, dispersion end diastole （DISPED）, and normalized 17 segmental volume-time curves. Results Evaluated by RT-3DE, LVEF was slightly lower compared with 2DE （63.2 ± 6.8% vs. 59.1 ± 6.4%, P 〈 0.0001）. Normal subjects had relatively uniform volumetric curves for all LV segments. In HCM patients, the segmental volumetric curves were dyssynchronous. Increased DDI and DISPED in end diastole were observed in patients with HCM （9.95 ± 3.75, 41.76 ± 17.19, P 〈 0.0001）, and not all abnormal volumetric segments occurred in the hypertrophic regions. Conclusions Patients with HCM have presented regional diastolic dyssynchrony in the diastole phase, and this preclinical lesion can be recognized by single-beat RT-3DE.展开更多
Oil spills in the sea have caused many serious environmental problems worldwide. In this study, carbon nanotube （CNT） sponges were used to cleanup oil slicks on sea waters. This method was compared with two traditio...Oil spills in the sea have caused many serious environmental problems worldwide. In this study, carbon nanotube （CNT） sponges were used to cleanup oil slicks on sea waters. This method was compared with two traditional representative sorbents, including polypropylene fiber fabric and woolen felt. The CNT sponges had a larger oil sorption capacity than the other two sorbents. The maximum oil sorption capacity （Qm） of the CNT sponge was 92.30 g/g, which was 12 to 13.5 times larger than the Qm of the other two sorbents （the Qm of the polypropylene fiber fabric and woolen felt were 7.45 and 6.74 g/g, respectively）. In addition, unlike the other two sorbents, the CNT sponge was super- hydrophobic and did not adsorb any water during oil spill cleanup. CNT sponges are potentially very useful for cleaning up oil spills from sea water.展开更多
Objective:Mental disorders of the elderly population in China deserve attention.Social health is significantly associated with depression.This study aimed to evaluate the rate of depressive symptoms and to test the re...Objective:Mental disorders of the elderly population in China deserve attention.Social health is significantly associated with depression.This study aimed to evaluate the rate of depressive symptoms and to test the relationships between social health and depressive symptoms among a large sample of community-dwelling elderly adults.Methods:We conducted a cross-sectional study among community-dwelling adults aged 60 years or above in Zhejiang Province,China.Face-to-face interviews were used to complete a structured questionnaire for all participants.We used the Social Health Scale for the Elderly(SHSE)to evaluate social health status and used the short form of the Geriatric Depression Scale to evaluate depressive symptoms.Multivariate logistic regression was used to evaluate the asso?ciation between social health status and depressive symptoms.Results:Of the total of 3757 participants included,1887(50.23%)were female,and the mean±standard deviation(SD)age was(70.0±8.3)years.The rate of depressive symptoms was 25.92%.The social health score was higher in non?depressed participants than in depressed participants(raw score 50.7 vs.48.3,P<0.001).Participants with"moderate”or"good”social health had a significantly lower risk of depressive symptoms than those with“poor"social health(odds ratio(OR)=0.55,95%con fide nee interval(Cl):0.46-0.66 for moderate social health;OR=0.45,95%Cl:0.35-0.60 for good social health).The association between social health and depressive symptoms was con sistent across several subgroups.Con clusi ons:Social health is signify cantly inversely associated with depressive symptoms.The SHSE may serve as an efficient screener to identify those elderly adults with social health deficits,but systematic assessment to guide intervention merits further investigation.展开更多
Severe crushing injuries to the distal forearm can preclude immediate hand replantation,with temporary ectopic implantation as a practicable option under special circumstances.This report describes a case of temporary...Severe crushing injuries to the distal forearm can preclude immediate hand replantation,with temporary ectopic implantation as a practicable option under special circumstances.This report describes a case of temporary ectopic hand implantation for a crush injury extending from the wrist to the middle third of the forearm,using the left foot as the recipient site.The hand was replanted onto the left forearm 3 months after the ectopic implantation,with functional gains seen by 18 months.Satisfactory ambulation was retained,with no reported foot pain.Temporary ectopic implantation is a pragmatic alternative under select circumstances.展开更多
基金funded by the National Natural Science Foundation of China(31970240 and 31770346)the National Key Research and Development Program of China(2016YFD0300203-3)the Key Scientific Research Projects of Colleges and Universities in Henan Province(19A180003).
文摘Asparagus setaceus is a popular ornamental plant cultivated in tropical and subtropical regions globally.Here,we constructed a chromosome-scale reference genome of A.setaceus to facilitate the investigation of its genome characteristics and evolution.Using a combination of Nanopore long reads,Illumina short reads,10×Genomics linked reads,and Hi-C data,we generated a high-quality genome assembly of A.setaceus covering 710.15 Mb,accounting for 98.63%of the estimated genome size.A total of 96.85%of the sequences were anchored to ten superscaffolds corresponding to the ten chromosomes.The genome of A.setaceus was predicted to contain 28,410 genes,25,649(90.28%)of which were functionally annotated.A total of 65.59%of the genome was occupied by repetitive sequences,among which long terminal repeats were predominant(42.51%of the whole genome).Evolutionary analysis revealed an estimated divergence time of A.setaceus from its close relative A.officinalis of~9.66 million years ago,and A.setaceus underwent two rounds of whole-genome duplication.In addition,762 specific gene families,96 positively selected genes,and 76 resistance(R)genes were detected and functionally predicted in A.setaceus.These findings provide new knowledge about the characteristics and evolution of the A.setaceus genome,and will facilitate comparative genetic and genomic research on the genus Asparagus.
基金supported by the National Natural Science Foundation of China(Grants No.10972134 and 11032007)
文摘Sediment layers containing contaminants play a significant role in environmental hydrodynamics. Experiments were conducted in order to characterize the relative roles of resuspended particles and pore water under different flow and sediment conditions. A conservative tracer （NaC1） and a reactive tracer （phosphate） were used as contaminants in the bottom sediment in a laboratory flume. The mixing between the overlying water and pore water occurred over a short time while the desorption of contaminants from fine-grained resuspended particles lasted a relatively long time. The effects of resuspended particles and pore water on the variations of release flux and concentration of contaminants in water with time under different hydrodynamic conditions were quantified. The results show that pore water dominated the initial release flux, which could be several orders of magnitude greater than the flux due to molecular diffusion. Flux contribution of desorption from sediment particles in the latter release could be equal to what was seen from pore water in the initial stage.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11475018 and 11974044)the National Key Research and Development Program of China(Grant 2016YFC1401001)。
文摘We experimentally investigate the effect of the hopper angle on the flow rate of grains discharged from a twodimensional horizontal hopper on a conveyor belt.The flow rate grows with the hopper angle,and finally reaches a plateau.The curve feature appears to be similar for different orifice widths and conveyor belt-driven velocities.On the basis of an empirical law of flow rate for a flat-bottom hopper,we propose a modified equation to describe the relation between the flow rate and hopper angle,which is in a good agreement with the experimental results.
文摘Objectives To assess the regional diastolic function in patients with hypertrophic cardiomyopathy （HCM） by using single-beat, real-time, three-dimensional echocardiography （RT-3DE）. Methods Sixty-five patients with HCM in sinus rhythm together with fifty age- and gender-matched normal controls were studied by two dimensional echocardiography （2DE） and RT-3DE. The parameters analyzed by RT-3DE included： left ventrieular （LV） volumes, left ventricular ejection fraction （LVEF）, end diastolic sphericity index （EDSI）, diastolic dyssynchrony index （DDI）, dispersion end diastole （DISPED）, and normalized 17 segmental volume-time curves. Results Evaluated by RT-3DE, LVEF was slightly lower compared with 2DE （63.2 ± 6.8% vs. 59.1 ± 6.4%, P 〈 0.0001）. Normal subjects had relatively uniform volumetric curves for all LV segments. In HCM patients, the segmental volumetric curves were dyssynchronous. Increased DDI and DISPED in end diastole were observed in patients with HCM （9.95 ± 3.75, 41.76 ± 17.19, P 〈 0.0001）, and not all abnormal volumetric segments occurred in the hypertrophic regions. Conclusions Patients with HCM have presented regional diastolic dyssynchrony in the diastole phase, and this preclinical lesion can be recognized by single-beat RT-3DE.
文摘Oil spills in the sea have caused many serious environmental problems worldwide. In this study, carbon nanotube （CNT） sponges were used to cleanup oil slicks on sea waters. This method was compared with two traditional representative sorbents, including polypropylene fiber fabric and woolen felt. The CNT sponges had a larger oil sorption capacity than the other two sorbents. The maximum oil sorption capacity （Qm） of the CNT sponge was 92.30 g/g, which was 12 to 13.5 times larger than the Qm of the other two sorbents （the Qm of the polypropylene fiber fabric and woolen felt were 7.45 and 6.74 g/g, respectively）. In addition, unlike the other two sorbents, the CNT sponge was super- hydrophobic and did not adsorb any water during oil spill cleanup. CNT sponges are potentially very useful for cleaning up oil spills from sea water.
基金Project supported by the Ministry of Science and Technology of the People’s Republic of China(No.2015FY111600)
文摘Objective:Mental disorders of the elderly population in China deserve attention.Social health is significantly associated with depression.This study aimed to evaluate the rate of depressive symptoms and to test the relationships between social health and depressive symptoms among a large sample of community-dwelling elderly adults.Methods:We conducted a cross-sectional study among community-dwelling adults aged 60 years or above in Zhejiang Province,China.Face-to-face interviews were used to complete a structured questionnaire for all participants.We used the Social Health Scale for the Elderly(SHSE)to evaluate social health status and used the short form of the Geriatric Depression Scale to evaluate depressive symptoms.Multivariate logistic regression was used to evaluate the asso?ciation between social health status and depressive symptoms.Results:Of the total of 3757 participants included,1887(50.23%)were female,and the mean±standard deviation(SD)age was(70.0±8.3)years.The rate of depressive symptoms was 25.92%.The social health score was higher in non?depressed participants than in depressed participants(raw score 50.7 vs.48.3,P<0.001).Participants with"moderate”or"good”social health had a significantly lower risk of depressive symptoms than those with“poor"social health(odds ratio(OR)=0.55,95%con fide nee interval(Cl):0.46-0.66 for moderate social health;OR=0.45,95%Cl:0.35-0.60 for good social health).The association between social health and depressive symptoms was con sistent across several subgroups.Con clusi ons:Social health is signify cantly inversely associated with depressive symptoms.The SHSE may serve as an efficient screener to identify those elderly adults with social health deficits,but systematic assessment to guide intervention merits further investigation.
文摘Severe crushing injuries to the distal forearm can preclude immediate hand replantation,with temporary ectopic implantation as a practicable option under special circumstances.This report describes a case of temporary ectopic hand implantation for a crush injury extending from the wrist to the middle third of the forearm,using the left foot as the recipient site.The hand was replanted onto the left forearm 3 months after the ectopic implantation,with functional gains seen by 18 months.Satisfactory ambulation was retained,with no reported foot pain.Temporary ectopic implantation is a pragmatic alternative under select circumstances.
