When studying the dam-break flow phenomenon,the basic hydrodynamic features of the dam-break flow at the gate location should be verified primarily.In this study,laboratory experiments were performed in a rectangular ...When studying the dam-break flow phenomenon,the basic hydrodynamic features of the dam-break flow at the gate location should be verified primarily.In this study,laboratory experiments were performed in a rectangular and horizontal flume with the same initial water head setting on the dry and wet downstream bed conditions.Water surface elevation was extracted through image analysis and validated by comparing with the data measured using a wave gauge.Temporal variation of the water surface elevation at the gate location,quantified in terms of high-speed video recorded images,can be divided into three stages,the sharp decreasing stage,the relatively steady stage,and the gradually decreasing stage.Applicability of several classic analytical solutions of the dam-break problem at the gate location was validated using present experimental data.Ritter's solution is effective for the dry bed condition while Stoker's solution could be applied to the wet bed case,and both are only applicable during the steady stage.Lin' solution reproduces the gate-site hydrographs well during both the relatively steady and the gradually decreasing stages,especially for the condition under which the down-upstream water depth ratio is smaller than 0.138.展开更多
OBJECTIVE: To investigate the efficacy and safety of Sodium tanshinone ⅡA sulfonate(STS) plus the conventional treatment on acute myocardial infarction(AMI) patients.METHODS: We searched several electrical databases ...OBJECTIVE: To investigate the efficacy and safety of Sodium tanshinone ⅡA sulfonate(STS) plus the conventional treatment on acute myocardial infarction(AMI) patients.METHODS: We searched several electrical databases and hand searched several Chinese medical journals up to January 2019. Randomized controlled trials(RCTs) comparing STS plus conventional treatment with conventional treatment were retrieved.Study screening, data extraction, quality assessment, and data analysis were conducted in accordance with the Cochrane standards.RESULTS: Sixteen trials involving 1383 people were included. The Meta-analysis showed STS combined with conventional treatment was a better treatment option than conventional treatment alone in reducing the risk of mortality, heart failure, arrhythmia and shock. In addition, STS was associated with improvement in left ventricular ejection fraction(LVEF) and left ventricular end diastolic dimension(LVEDD). No significant difference of STS was found on recurrent angina and recurrent AMI. However,the safety of STS remained uncertain for limited data.CONCLUSION: Compared with conventional treatment alone, STS combined with conventional treatment may provide more benefits for patients with AMI. Due to the fact that the overall quality of all included trials is generally low, further large-scale high quality trials are warranted.展开更多
基金financially supported by the Natural Science Foundation of Zhejiang Province,China(No.LR14E090002)the National Natural Science Foundation of China(No.11632012)the Open Research Fund Program of State key Laboratory of Hydroscience and Engineering(No.sklhse-2016-B-02)
文摘When studying the dam-break flow phenomenon,the basic hydrodynamic features of the dam-break flow at the gate location should be verified primarily.In this study,laboratory experiments were performed in a rectangular and horizontal flume with the same initial water head setting on the dry and wet downstream bed conditions.Water surface elevation was extracted through image analysis and validated by comparing with the data measured using a wave gauge.Temporal variation of the water surface elevation at the gate location,quantified in terms of high-speed video recorded images,can be divided into three stages,the sharp decreasing stage,the relatively steady stage,and the gradually decreasing stage.Applicability of several classic analytical solutions of the dam-break problem at the gate location was validated using present experimental data.Ritter's solution is effective for the dry bed condition while Stoker's solution could be applied to the wet bed case,and both are only applicable during the steady stage.Lin' solution reproduces the gate-site hydrographs well during both the relatively steady and the gradually decreasing stages,especially for the condition under which the down-upstream water depth ratio is smaller than 0.138.
基金Supported by Project of Administration of Traditional Chinese Medicine of Guangdong Province Clinical Study of the Effect of TanshinoneⅡA Sodium Sulfonate on Coronary Microcirculation in Patients with Acute Coronary Syndrome(No. 20181126)Project of Special Clinical Research Fund for TCM Science and Technology of Guangdong Provincial Hospital of Chinese Medicine Clinical Study of the Effect of TanshinoneⅡA Sodium Sulfonate on Coronary Microcirculation in Patients with Acute Coronary Syndrome (No.YN2018QL06)Project of Department of Education of Guangdong Province Acute Myocardial Infarction Chinese Medicine Prevention and Treatment Team (No. 2020KT1207)。
文摘OBJECTIVE: To investigate the efficacy and safety of Sodium tanshinone ⅡA sulfonate(STS) plus the conventional treatment on acute myocardial infarction(AMI) patients.METHODS: We searched several electrical databases and hand searched several Chinese medical journals up to January 2019. Randomized controlled trials(RCTs) comparing STS plus conventional treatment with conventional treatment were retrieved.Study screening, data extraction, quality assessment, and data analysis were conducted in accordance with the Cochrane standards.RESULTS: Sixteen trials involving 1383 people were included. The Meta-analysis showed STS combined with conventional treatment was a better treatment option than conventional treatment alone in reducing the risk of mortality, heart failure, arrhythmia and shock. In addition, STS was associated with improvement in left ventricular ejection fraction(LVEF) and left ventricular end diastolic dimension(LVEDD). No significant difference of STS was found on recurrent angina and recurrent AMI. However,the safety of STS remained uncertain for limited data.CONCLUSION: Compared with conventional treatment alone, STS combined with conventional treatment may provide more benefits for patients with AMI. Due to the fact that the overall quality of all included trials is generally low, further large-scale high quality trials are warranted.
