This research presents the results of investigation of laser_polarization fluorescence ofbiological layers(histological sections,cy tological smears)in the task of diagnostics and differ-en tiation of early stages of ...This research presents the results of investigation of laser_polarization fluorescence ofbiological layers(histological sections,cy tological smears)in the task of diagnostics and differ-en tiation of early stages of cancer:Dysplasia-cervical microinvasive carcinoma of cervic uteri.The analytical conditions of polarization-optimal probing of biological layers were determinedbasing on the model of linear birefringence and dichroism of birefringent(fibrllar,porphyrin)networks.The technique of polarization-variable laser autofluorescence was developed andexperimentally tested.The objective criteria(statistical moments)of differentiation of histo-logical sections autofluorescent images of endometrium biopsy and cytological smears of itmucous coat were defined.The operational characteristics(sensitivity,speifity,accuracy)ofthis technique were determined concerning the positions of probative medicine,and clinical efficiency.展开更多
The results of singular approach usage in the tasks of description and classification of appearance of optical anisotropy of different types of phase-inhomogeneous biological layers(surface-scattering,optically thin a...The results of singular approach usage in the tasks of description and classification of appearance of optical anisotropy of different types of phase-inhomogeneous biological layers(surface-scattering,optically thin and optically thick)have been presented.The characteristic values of the fourth Stokes vector parameter(S_(4)=0-linear polarization-(L-state);S_(4)=±1-circular polarization-(C-state))have been chosen as the main analytical tool descni bing polarization-singular states.The value of S.has been deternined by the value of phase shift betwoen the ort hogonal components of amplitude in the point of biological layer laser image and therefore is azimuthally stable.Hence,statistic moments of the first to the fourth orders characterizing the distribution of the amount of characteristic values S4=0;S_(4)=±1 have been used for definition and di ferentiation of optical properties of diferent types of biological layers-surface scattering,optically thin and optically thick human skin.展开更多
文摘This research presents the results of investigation of laser_polarization fluorescence ofbiological layers(histological sections,cy tological smears)in the task of diagnostics and differ-en tiation of early stages of cancer:Dysplasia-cervical microinvasive carcinoma of cervic uteri.The analytical conditions of polarization-optimal probing of biological layers were determinedbasing on the model of linear birefringence and dichroism of birefringent(fibrllar,porphyrin)networks.The technique of polarization-variable laser autofluorescence was developed andexperimentally tested.The objective criteria(statistical moments)of differentiation of histo-logical sections autofluorescent images of endometrium biopsy and cytological smears of itmucous coat were defined.The operational characteristics(sensitivity,speifity,accuracy)ofthis technique were determined concerning the positions of probative medicine,and clinical efficiency.
文摘The results of singular approach usage in the tasks of description and classification of appearance of optical anisotropy of different types of phase-inhomogeneous biological layers(surface-scattering,optically thin and optically thick)have been presented.The characteristic values of the fourth Stokes vector parameter(S_(4)=0-linear polarization-(L-state);S_(4)=±1-circular polarization-(C-state))have been chosen as the main analytical tool descni bing polarization-singular states.The value of S.has been deternined by the value of phase shift betwoen the ort hogonal components of amplitude in the point of biological layer laser image and therefore is azimuthally stable.Hence,statistic moments of the first to the fourth orders characterizing the distribution of the amount of characteristic values S4=0;S_(4)=±1 have been used for definition and di ferentiation of optical properties of diferent types of biological layers-surface scattering,optically thin and optically thick human skin.