Social dysfunction is a risk factor for several neuropsychiatric illnesses.Previous studies have shown that the lateral septum(LS)-related pathway plays a critical role in mediating social behaviors.Howeve r,the role ...Social dysfunction is a risk factor for several neuropsychiatric illnesses.Previous studies have shown that the lateral septum(LS)-related pathway plays a critical role in mediating social behaviors.Howeve r,the role of the connections between the LS and its downstream brain regions in social behavio rs remains unclea r.In this study,we conducted a three-chamber test using electrophysiological and chemogenetic approaches in mice to determine how LS projections to ventral CA1(vCA1)influence sociability.Our res ults showed that gamma-aminobutyric acid(GABA)-e rgic neuro ns were activated following social experience,and that social behavio rs were enhanced by chemogenetic modulation of these neurons.Moreover,LS GABAergic neurons extended their functional neural connections via vCA1 glutamatergic pyramidal neurons,and regulating LSGABA→vCA1Gluneural projections affected social behaviors,which were impeded by suppressing LSprojecting vCA1 neuronal activity or inhibiting GABAAreceptors in vCA1.These findings support the hypothesis that LS inputs to the vCA1 can control social prefe rences and social novelty behaviors.These findings provide new insights rega rding the neural circuits that regulate sociability.展开更多
Along with the environmental pollution, the scarcity of clean water seriously threatens the sustainable development of human society.Recently, the rapid development of solar evaporators has injected new vitality into ...Along with the environmental pollution, the scarcity of clean water seriously threatens the sustainable development of human society.Recently, the rapid development of solar evaporators has injected new vitality into the field of water purification. However, the industry faces a considerable challenge of achieving comprehensive purification of ions, especially the efficient removal of mercury ions. In this work, we introduce an ideal mercury-removal platform based on facilely and cost-effectively synthesized polysulfide nanoparticles(PSNs). Further development of PSN-functionalized reduced graphene oxide(PSN-rGO) aerogel evaporator results in achieving a high evaporation rate of 1.55 kg m^(-2)h^(-1)with energy efficiency of 90.8% under 1 sun. With the merits of interconnected porous structure and adsorption ability, the photothermal aerogel presents overall purification of heavy metal ions from wastewater. During solar desalination, salt ions can be rejected with long-term stability. Compared with traditional water purification technologies, this highly efficient solar evaporator provides a new practical method to utilize clean energy for clean water production.展开更多
Magnetic tunnel junction(MTJ) based spin transfer torque magnetic random access memory(STT-MRAM) has been gaining tremendous momentum in high performance microcontroller(MCU) applications. As e Flash-replacement type ...Magnetic tunnel junction(MTJ) based spin transfer torque magnetic random access memory(STT-MRAM) has been gaining tremendous momentum in high performance microcontroller(MCU) applications. As e Flash-replacement type MRAM approaches mass production, there is an increasing demand for non-volatile RAM(nv RAM) technologies that offer fast write speed and high endurance. In this work, we demonstrate highly reliable 4 Mb nv RAM type MRAM suitable for industry and auto grade-1 applications. This nv RAM features retention over 10 years at 125 ℃, endurance of 1 × 10^(12)cycles with 20 ns write speed, making it ideal for applications requiring both high speed and broad temperature ranges. By employing innovative MTJ materials, process engineering, and a co-optimization of process and design, reliable read and write performance across the full temperature range between -40 to 125 ℃, and array yield that meets sub-1 ppm error rate was significantly improved from 0 to above 95%, a concrete step toward applications.展开更多
Encryption materials represent a major direction of information security,but it is challenging to realize the ideal security combining the complete hiding of complex coding,stability in transmission,camouflage,and rel...Encryption materials represent a major direction of information security,but it is challenging to realize the ideal security combining the complete hiding of complex coding,stability in transmission,camouflage,and reliable decoding.Herein,we report an innovative strategy for rationally constructing encryption composite materials with high security and portability.Compared with common colloidal photonic watermarks,our encrypted optical devices are composed of thermoplastic polyurethanes(TPU)protective layers,polystyrene(PS)switching layers and a Cd S coding layer.The optical shielding properties and phase state transition of PS layers enable high-level encoding and decoding security through thermal activation of light transmittance control.Meanwhile,the Cd S layer can be clearly revealed in decoding mode because of the high refractive index.Besides,the confinement protection of integrated TPU films prevents the trilayer quasi-amorphous heterostructure from damage.To establish the practical advantage,portable information carriers can be prepared for camouflage.Accordingly,the reliable encoding and decoding system,and ability to integrate with easy-to-carry products,make our composites a potentially high-security encryption device for anti-fraud technology.展开更多
基金supported by the National Natural Science Foundation of China,No.82171521(to CL)the Special Funds ofTaishan Scholars Project of Shandong Province,No.tsqn202211368(to CL)+2 种基金the Natural Science Foundation of Shandong Province,Nos.ZR2022YQ65(to CL),ZR2021MH073(to CL),ZR2019PH109(to WW)the Projects of Medical and Health Technology Development Program in Shandong Province,China,Nos.202003090720(to DZ),202003070728(to JL),2019 WS329(to DW)the Scientific Research Foundation of Binzhou Medical University,No.BY2018KJ21(to DW)。
文摘Social dysfunction is a risk factor for several neuropsychiatric illnesses.Previous studies have shown that the lateral septum(LS)-related pathway plays a critical role in mediating social behaviors.Howeve r,the role of the connections between the LS and its downstream brain regions in social behavio rs remains unclea r.In this study,we conducted a three-chamber test using electrophysiological and chemogenetic approaches in mice to determine how LS projections to ventral CA1(vCA1)influence sociability.Our res ults showed that gamma-aminobutyric acid(GABA)-e rgic neuro ns were activated following social experience,and that social behavio rs were enhanced by chemogenetic modulation of these neurons.Moreover,LS GABAergic neurons extended their functional neural connections via vCA1 glutamatergic pyramidal neurons,and regulating LSGABA→vCA1Gluneural projections affected social behaviors,which were impeded by suppressing LSprojecting vCA1 neuronal activity or inhibiting GABAAreceptors in vCA1.These findings support the hypothesis that LS inputs to the vCA1 can control social prefe rences and social novelty behaviors.These findings provide new insights rega rding the neural circuits that regulate sociability.
基金supported by the National Natural Science Foundation of China(21878043,21576039,21421005 and U1608223)Program for Innovative Research Team in University(IRT_13R06)+4 种基金Fundamental Research Funds for the Central Universities(DUT18ZD218)Talent Fund of Shandong Collaborative Innovation Center of Eco-Chemical Engineering(XTCXYX04)Program for the Innovative Talents of Higher Learning Institutions of Liaoning(LCR2018066)Dalian High-level Talents Innovation Support Program(2019RD06)the Liaoning Revitalization Talent Program(1801006).
文摘Along with the environmental pollution, the scarcity of clean water seriously threatens the sustainable development of human society.Recently, the rapid development of solar evaporators has injected new vitality into the field of water purification. However, the industry faces a considerable challenge of achieving comprehensive purification of ions, especially the efficient removal of mercury ions. In this work, we introduce an ideal mercury-removal platform based on facilely and cost-effectively synthesized polysulfide nanoparticles(PSNs). Further development of PSN-functionalized reduced graphene oxide(PSN-rGO) aerogel evaporator results in achieving a high evaporation rate of 1.55 kg m^(-2)h^(-1)with energy efficiency of 90.8% under 1 sun. With the merits of interconnected porous structure and adsorption ability, the photothermal aerogel presents overall purification of heavy metal ions from wastewater. During solar desalination, salt ions can be rejected with long-term stability. Compared with traditional water purification technologies, this highly efficient solar evaporator provides a new practical method to utilize clean energy for clean water production.
基金supported by National Science and Technology Major Project (2020AAA0109003)the support from Hangzhou Innovation Team Program (TD2022018)。
文摘Magnetic tunnel junction(MTJ) based spin transfer torque magnetic random access memory(STT-MRAM) has been gaining tremendous momentum in high performance microcontroller(MCU) applications. As e Flash-replacement type MRAM approaches mass production, there is an increasing demand for non-volatile RAM(nv RAM) technologies that offer fast write speed and high endurance. In this work, we demonstrate highly reliable 4 Mb nv RAM type MRAM suitable for industry and auto grade-1 applications. This nv RAM features retention over 10 years at 125 ℃, endurance of 1 × 10^(12)cycles with 20 ns write speed, making it ideal for applications requiring both high speed and broad temperature ranges. By employing innovative MTJ materials, process engineering, and a co-optimization of process and design, reliable read and write performance across the full temperature range between -40 to 125 ℃, and array yield that meets sub-1 ppm error rate was significantly improved from 0 to above 95%, a concrete step toward applications.
基金the National Natural Science Foundation of China(21878043,21576039,21421005 and U1608223)the Program for Innovative Research Team in University(IRT13R06)+1 种基金the Fundamental Research Funds for the Central Universities(DUT18ZD218)the Talent Fund of Shandong Collaborative Innovation Center of Eco-Chemical Engineering(XTCXYX04)。
文摘Encryption materials represent a major direction of information security,but it is challenging to realize the ideal security combining the complete hiding of complex coding,stability in transmission,camouflage,and reliable decoding.Herein,we report an innovative strategy for rationally constructing encryption composite materials with high security and portability.Compared with common colloidal photonic watermarks,our encrypted optical devices are composed of thermoplastic polyurethanes(TPU)protective layers,polystyrene(PS)switching layers and a Cd S coding layer.The optical shielding properties and phase state transition of PS layers enable high-level encoding and decoding security through thermal activation of light transmittance control.Meanwhile,the Cd S layer can be clearly revealed in decoding mode because of the high refractive index.Besides,the confinement protection of integrated TPU films prevents the trilayer quasi-amorphous heterostructure from damage.To establish the practical advantage,portable information carriers can be prepared for camouflage.Accordingly,the reliable encoding and decoding system,and ability to integrate with easy-to-carry products,make our composites a potentially high-security encryption device for anti-fraud technology.
