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外延生长具有厚度可调导电属性的非层状二维碲化锰纳米片用于p-型场效应晶体管和优异的接触电极
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作者 贺梦菲 陈超 +10 位作者 唐月 孟思 王遵法 王立煜 行家宝 张欣宇 黄佳慧 卢江波 井红梅 刘翔宇 徐华 《物理化学学报》 北大核心 2025年第2期107-115,共9页
碲化锰(manganese telluride,MnTe)作为一种新兴的非层状二维材料,因其优异的性质以及在下一代电子和光电子器件中的巨大潜力,而受到研究学者们的广泛关注。然而,目前超薄二维MnTe的可控合成仍然是一个巨大的挑战,这限制了对其基础性质... 碲化锰(manganese telluride,MnTe)作为一种新兴的非层状二维材料,因其优异的性质以及在下一代电子和光电子器件中的巨大潜力,而受到研究学者们的广泛关注。然而,目前超薄二维MnTe的可控合成仍然是一个巨大的挑战,这限制了对其基础性质的研究和应用的深入探索。本文采用化学气相沉积方法成功合成了大面积的MnTe纳米片,并探究了其厚度对电学性质和器件应用的影响。通过提高MnTe纳米片的生长温度,样品厚度逐渐增加,晶畴尺寸从10μm增至125μm,形貌从三角形逐渐过度到六边形,最终生长成高度对称的圆形。结构表征和二次谐波测试表明,所制备的MnTe纳米片具有高度的结晶质量和优异的二阶非线性光学性质。此外,通过对不同厚度MnTe纳米片的电学输运测试,发现随着厚度从薄到厚,其导电特性从p型半导体逐渐转变为半金属。因此,利用半导体特性的薄层MnTe纳米片构建的光电探测器展现出出色的光响应性能。而将金属特性的厚层MnTe作为MoS2场效应晶体管的接触电极,显著提高了器件性能,如载流子迁移率可从12.76 cm^(2)·V^(-1)·s^(-1)(Au接触)提升到47.34 cm^(2)·V^(-1)·s^(-1)(MnTe接触)。 展开更多
关键词 二维材料 碲化锰 化学气相沉积 场效应晶体管 光电探测器 接触电极
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第56届国际化学奥林匹克试题(实验部分)
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作者 郑捷 刘欲文 +2 位作者 陈超 张龙 裴坚 《大学化学》 2024年第12期403-412,共10页
酸碱指示剂酸碱指示剂是在酸性和碱性下可以呈现不同颜色的物质。由于每种指示剂有不同的酸碱电离平衡常数,不同指示剂变色的pH值范围也不同,因此,在给定pH值的溶液中,一种指示剂可能显示为酸性形态,而另一种则显示为碱性形态。在本实验... 酸碱指示剂酸碱指示剂是在酸性和碱性下可以呈现不同颜色的物质。由于每种指示剂有不同的酸碱电离平衡常数,不同指示剂变色的pH值范围也不同,因此,在给定pH值的溶液中,一种指示剂可能显示为酸性形态,而另一种则显示为碱性形态。在本实验中,你将使用四种指示剂。其中一种指示剂会在两个不同的pH值下发生明显的变色。你的目标是找出这些指示剂变色时对应溶液pH值的顺序,并根据不同的pH值鉴别其他八种未知溶液。你将首先用TLC实验确定四种不同指示剂的性质。 展开更多
关键词 酸碱指示剂 电离平衡常数 溶液PH值 酸性 化学 变色
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第56届国际化学奥林匹克试题(理论部分)
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作者 刘欲文 郑捷 +2 位作者 陈超 张龙 裴坚 《大学化学》 2024年第12期385-402,共18页
第1题氨利用氮气和氢气为原料生产氨气的哈伯-博世(Haber–Bosch)工艺是历史上影响最大的化工工艺之一,估计其对粮食的增产维持了当今约一半人口的生活所需。该工艺过程通常在400℃和100 bar的恒温恒压条件下进行。反应物和产物在Fe基... 第1题氨利用氮气和氢气为原料生产氨气的哈伯-博世(Haber–Bosch)工艺是历史上影响最大的化工工艺之一,估计其对粮食的增产维持了当今约一半人口的生活所需。该工艺过程通常在400℃和100 bar的恒温恒压条件下进行。反应物和产物在Fe基催化剂的作用下在反应器中建立了化学平衡。N2、H2和NH3的标准气相热化学数据如下所示。假设反应的焓和熵与温度无关。 展开更多
关键词 化工工艺 恒温恒压 化学平衡 工艺过程
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“通关利窍”针刺法治疗卒中后吞咽困难立法辨证及机制探讨 被引量:1
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作者 黄泓文 陈超 樊小农 《Chinese Medicine and Natural Products》 CAS 2024年第2期56-60,共5页
由国医大师、中国工程院院士石学敏创立的"通关利窍"针刺法衍生于著名的"醒脑开窍"针刺法,以"调神"为立法辨证取穴的根本。选用内关、人中、三阴交作为主穴,以调神醒脑、滋补肝肾,此为治"本";... 由国医大师、中国工程院院士石学敏创立的"通关利窍"针刺法衍生于著名的"醒脑开窍"针刺法,以"调神"为立法辨证取穴的根本。选用内关、人中、三阴交作为主穴,以调神醒脑、滋补肝肾,此为治"本";选用了颈项部的廉泉、翳风、完骨、风池穴以"利窍",此为治"标"。该针刺法以深刺为特色,契合了现代吞咽功能解剖。该针法能够通过改善脑供血及代谢、促进神经功能重塑等促进卒中后吞咽困难功能的改善。 展开更多
关键词 “通关利窍”针刺法 卒中后吞咽困难 调神 双悬吊机制 神经功能重塑
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BiOBr nanosheets coupling with biomass carbon derived from locust leaves for enhanced photocatalytic degradation of rhodamine B 被引量:1
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作者 Hongtao Wang Xiangrui Fan +4 位作者 Mingming Yan Tianyu Guo Xingfa Li chao chen Yu Qi 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第10期31-43,共13页
A series of BiOBr@biomass carbon derived from locust leaves materials(BiOBr@BC)were fabricated and the photocatalytic property was investigated for photocatalytic degradation of rhodamine B(RhB)under visible light.The... A series of BiOBr@biomass carbon derived from locust leaves materials(BiOBr@BC)were fabricated and the photocatalytic property was investigated for photocatalytic degradation of rhodamine B(RhB)under visible light.The morphology,structure and photoelectrochemical properties of the photocatalysts were characterized by means of SEM,TEM,XRD,XPS,FT-IR,BET,PL,UV-vis/DRS,and EIS techniques.The results showed that the introduction of BC significantly enhanced the photocatalytic activity.When the content of biomass carbon(BC)in a composite is 3%(based on the mass of BiOBr),the obtained BiOBr@BC-3 exhibits excellent photocatalytic activity,degrading 99%of RhB within 20 min.The excellent degradation efficiency after the introduction of BC can be attributed to the enhanced visible light absorption,narrower band gap,and fast electron-hole pair separation rate.The photocatalytic mechanism on the degradation of RhB was illustrated based on the radicals'trapping experiments and semiconductor energy band position.The proposed material is expected to be of significant application value in the field of wastewater treatment. 展开更多
关键词 DEGRADATION Rhodamine B ADSORPTION BiOBr Renewable energy
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Deep near infrared light-excited stable synergistic photodynamic and photothermal therapies based on P-IR890 nano-photosensitizer constructed via a non-cyanine dye
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作者 Dawei Jiang chao chen +12 位作者 Peng Dai Caiyan Li Zhiyi Feng Na Dong Fenzan Wu Junpeng Xu PingWu Liuxi Chu Shengcun Li Xiaokun Li Youjun Yang Weian Zhang Zhouguang Wang 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2024年第5期152-165,共14页
The cyanine dyes represented by IR780 can achieve synergistic photodynamic therapy(PDT)and photothermal therapy(PTT)under the stimulation of near-infrared(NIR)light(commonly 808 nm).Unfortunately,the stability of NIR-... The cyanine dyes represented by IR780 can achieve synergistic photodynamic therapy(PDT)and photothermal therapy(PTT)under the stimulation of near-infrared(NIR)light(commonly 808 nm).Unfortunately,the stability of NIR-excited cyanine dyes is not satisfactory.These cyanine dyes can be attacked by self-generated reactive oxygen species(ROS)during PDT processes,resulting in structural damage and rapid degradation,which is fatal for phototherapy.To address this issue,a novel non-cyanine dye(IR890)was elaborately designed and synthesized by our team.The maximum absorption wavelength of IR890 was located in the deep NIR region(ca.890 nm),which was beneficial for further improving tissue penetration depth.Importantly,IR890 exhibited good stability when continuously illuminated by deep NIR light.To improve the hydrophilicity and biocompatibility,the hydrophobic IR890 dye was grafted onto the side chain of hydrophilic polymer(POEGMA-b-PGMA-g-C≡CH)via click chemistry.Then,the synthesized POEGMA-b-PGMA-g-IR890 amphiphilic polymerwas utilized to prepare P-IR890 nano-photosensitizer via self-assembly method.Under irradiation with deep NIR light(850 nm,0.5 W/cm^(2),10 min),the dye degradation rate of P-IR890 was less than 5%.However,IR780 was almost completely degraded with the same light output power density and irradiation duration.In addition,P-IR890 could stably generate a large number of ROS and heat at the same time.It was rarely reported that the stable synergistic combination therapy of PDT and PTT could be efficiently performed by a single photosensitizer via irradiation with deep NIR light.P-IR890 exhibited favorable anti-tumor outcomes through apoptosis pathway.Therefore,the P-IR890 could provide a new insight into the design of photosensitizers and new opportunities for synergistic combination therapy of PDT and PTT. 展开更多
关键词 Photodynamic therapy Photothermal therapy IR780 Non-cyanine dye Deep near infrared light
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Pairing correlation of the kagome-lattice Hubbard model with the nearest-neighbor interaction
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作者 chen Yang chao chen +2 位作者 Runyu Ma Ying Liang Tianxing Ma 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第10期41-45,共5页
A recently discovered family of kagome lattice materials,AV_(3)Sb_(5)(A=K,Rb,Cs),has attracted great interest,especiallyin the debate over their dominant superconducting pairing symmetry.To explore this issue,we study... A recently discovered family of kagome lattice materials,AV_(3)Sb_(5)(A=K,Rb,Cs),has attracted great interest,especiallyin the debate over their dominant superconducting pairing symmetry.To explore this issue,we study the superconductingpairing behavior within the kagome-lattice Hubbard model through the constrained path Monte Carlo method.It isfound that doping around the Dirac point generates a dominant next-nearest-neighbor-d pairing symmetry driven by on-siteCoulomb interaction U.However,when considering the nearest-neighbor interaction V,it may induce nearest-neighbor-ppairing to become the preferred pairing symmetry.Our results provide useful information to identify the dominant superconductingpairing symmetry in the AV_(3)Sb_(5)family. 展开更多
关键词 kagome-lattice Hubbard model SUPERCONDUCTIVITY pairing symmetry CPMC
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Effect of energy density on microstructure and mechanical properties of Ta−33Ti alloy prepared via laser powder bed fusion
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作者 Jia-qi ZHANG chao chen +5 位作者 Dan LI Zhao-wen GENG Peng PAN Guo-hua WANG Ke-chao ZHOU Jian-ling LIU 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第12期3919-3934,共16页
The influence of laser process parameters on the densification,phase composition,microstructure,and mechanical properties of Ta−33wt.%Ti alloy prepared via laser powder bed fusion(LPBF)was investigated.The results sho... The influence of laser process parameters on the densification,phase composition,microstructure,and mechanical properties of Ta−33wt.%Ti alloy prepared via laser powder bed fusion(LPBF)was investigated.The results show that fully dense and homogeneous Ta−Ti parts can be obtained from LPBF with appropriate energy input.The cellular and dendritic structures were formed due to constitutional undercooling.Transmission electron microscopy(TEM)analysis showed that the lamellarα″phase within the cellular structures preferred to concentrate at the cellular boundaries owing to the elemental micro-segregation in the solidification front.The samples fabricated under the energy density of 166.7 J/mm^(3) had a favorable ultimate tensile strength of 806 MPa and an excellent Young’s modulus of 36.7 GPa. 展开更多
关键词 Ta−Ti alloy laser powder bed fusion cellular and dendritic structures constitutional undercooling
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Ghrelin inhibits autophagy mediated by AKT/mTOR pathway to ameliorate retinal angiogenesis induced by high glucose stress
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作者 Jiang-Li Fan Rong Li +3 位作者 Min Zhang chao chen Guo-Min Yao Ling-Xiao Zhou 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第5期785-793,共9页
AIM:To observe the effect of ghrelin,a growth hormonereleasing peptide,on retinal angiogenesis in vitro under high glucose(HG)stress and to explore the possible mechanism of autophagy.METHODS:Human retinal microvascul... AIM:To observe the effect of ghrelin,a growth hormonereleasing peptide,on retinal angiogenesis in vitro under high glucose(HG)stress and to explore the possible mechanism of autophagy.METHODS:Human retinal microvascular endothelial cells(HRMECs)were treated with high concentration of glucose alone or in combination with ghrelin.The cell migration,tube formation and the expression of the autophagy-related proteins LC3-II/I,Beclin-1,p62,phosphorylated AKT(p-AKT)/AKT and phosphorylated mammalian target of rapamycin(p-mTOR)/mTOR were detected.Then,to clarify the correlation between ghrelin effect and autophagy,AKT inhibitor VIII was adopted to treat HRMECs,and cell migration,tube formation as well as the protein expressions of LC3-II/I,Beclin-1 and p62 were observed.RESULTS:Under HG stress,ghrelin inhibited migration and tube formation of HRMECs.Ghrelin inhibited the increases in the protein levels of LC3-II/I,Beclin-1 and the decreases in the protein levels of p62,p-AKT/AKT and p-mTOR/mTOR induced by HG stress.Moreover,under the action of AKT/mTOR pathway inhibitors,the effects of ghrelin on migration and tube formation were both reduced.In addition,the expression of LC3-II/I and Beclin-1 were significantly up-regulated and the expression of p62 was down-regulated.CONCLUSION:Retinal angiogenesis under in vitro HG stress can be inhibited by ghrelin through activating AKT/mTOR pathway to inhibit autophagy. 展开更多
关键词 GHRELIN retinal endothelial cell ANGIOGENESIS AUTOPHAGY STRESS
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Image Recognition Model of Fraudulent Websites Based on Image Leader Decision and Inception-V3 Transfer Learning
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作者 Shengli Zhou cheng Xu +3 位作者 Rui Xu Weijie Ding chao chen Xiaoyang Xu 《China Communications》 SCIE CSCD 2024年第1期215-227,共13页
The fraudulent website image is a vital information carrier for telecom fraud.The efficient and precise recognition of fraudulent website images is critical to combating and dealing with fraudulent websites.Current re... The fraudulent website image is a vital information carrier for telecom fraud.The efficient and precise recognition of fraudulent website images is critical to combating and dealing with fraudulent websites.Current research on image recognition of fraudulent websites is mainly carried out at the level of image feature extraction and similarity study,which have such disadvantages as difficulty in obtaining image data,insufficient image analysis,and single identification types.This study develops a model based on the entropy method for image leader decision and Inception-v3 transfer learning to address these disadvantages.The data processing part of the model uses a breadth search crawler to capture the image data.Then,the information in the images is evaluated with the entropy method,image weights are assigned,and the image leader is selected.In model training and prediction,the transfer learning of the Inception-v3 model is introduced into image recognition of fraudulent websites.Using selected image leaders to train the model,multiple types of fraudulent websites are identified with high accuracy.The experiment proves that this model has a superior accuracy in recognizing images on fraudulent websites compared to other current models. 展开更多
关键词 fraudulent website image leaders telecom fraud transfer learning
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Exploring the Roles of Single Atom in Hydrogen Peroxide Photosynthesis
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作者 Kelin He Zimo Huang +3 位作者 chao chen Chuntian Qiu Yu Lin Zhong Qitao Zhang 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第2期32-67,共36页
This comprehensive review provides a deep exploration of the unique roles of single atom catalysts(SACs)in photocatalytic hydrogen peroxide(H_(2)O_(2))production.SACs offer multiple benefits over traditional catalysts... This comprehensive review provides a deep exploration of the unique roles of single atom catalysts(SACs)in photocatalytic hydrogen peroxide(H_(2)O_(2))production.SACs offer multiple benefits over traditional catalysts such as improved efficiency,selectivity,and flexibility due to their distinct electronic structure and unique properties.The review discusses the critical elements in the design of SACs,including the choice of metal atom,host material,and coordination environment,and how these elements impact the catalytic activity.The role of single atoms in photocatalytic H_(2)O_(2)production is also analysed,focusing on enhancing light absorption and charge generation,improving the migration and separation of charge carriers,and lowering the energy barrier of adsorption and activation of reactants.Despite these advantages,several challenges,including H_(2)O_(2)decomposition,stability of SACs,unclear mechanism,and low selectivity,need to be overcome.Looking towards the future,the review suggests promising research directions such as direct utilization of H_(2)O_(2),high-throughput synthesis and screening,the creation of dual active sites,and employing density functional theory for investigating the mechanisms of SACs in H_(2)O_(2)photosynthesis.This review provides valuable insights into the potential of single atom catalysts for advancing the field of photocatalytic H_(2)O_(2)production. 展开更多
关键词 Single atom catalysts H_(2)O_(2)photosynthesis Catalyst design and optimization
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Physiological and Biochemical Responses of Perennial Ryegrass Mixed Planting with Legumes under Heavy Metal Pollution
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作者 Yi Xi Li Zhang +2 位作者 Yanhong Xu Wei cheng chao chen 《Phyton-International Journal of Experimental Botany》 SCIE 2024年第7期1749-1765,共17页
In artificially controlled pot experiments,perennial ryegrass was mixed with other leguminous plants(white clo-ver and alfalfa)and treated with lead,zinc and cadmium(337 mg·kg^(-1),648 mg·kg^(-1),and 9 mg... In artificially controlled pot experiments,perennial ryegrass was mixed with other leguminous plants(white clo-ver and alfalfa)and treated with lead,zinc and cadmium(337 mg·kg^(-1),648 mg·kg^(-1),and 9 mg·kg^(-1),respectively)to simulate compound pollution conditions.The results showed that the concentrations of heavy metals,trans-port factors,and bioconcentration factors in mixed planting of ryegrass decreased compared with those in mono-culture.Regardless of whether heavy metal pollution was introduced,mixed planting increased the aboveground and underground biomasses of ryegrass.The different mixed planting treatments had no significant impact on the chlorophyll concentration of ryegrass.The mowing time,mixed planting treatment,and heavy metal treatment had impacts on antioxidant and osmotic adjustment substances,and there were some interactions.The mixed planting treatment did not significantly affect glutathione concentration,cysteine concentration,or nonprotein thiol.Mixed planting generally increased the nitrogen and phosphorus concentrations of ryegrass while reducing the stoichiometric ratio of carbon,nitrogen,and phosphorus.These results suggest that the mixed planting of ryegrass with legumes promotes the growth of ryegrass in the presence of high concentrations of heavy metal pollution.However,it does not enhance the ability of ryegrass to remediate heavy metal pollution in the soil. 展开更多
关键词 Perennial ryegrass mixed planting PHYTOREMEDIATION LEAD ZINC and cadmium soil pollution
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Manipulating the Spatial Structure of Second-Order Quantum Coherence Using Entangled Photons
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作者 黄双印 高菁 +10 位作者 任志成 程子默 朱文正 薛舒天 娄严超 刘志峰 陈超 朱飞 杨立平 汪喜林 王慧田 《Chinese Physics Letters》 SCIE EI CAS CSCD 2024年第7期58-73,共16页
High-order quantum coherence reveals the statistical correlation of quantum particles. Manipulation of quantum coherence of light in the temporal domain enables the production of the single-photon source, which has be... High-order quantum coherence reveals the statistical correlation of quantum particles. Manipulation of quantum coherence of light in the temporal domain enables the production of the single-photon source, which has become one of the most important quantum resources. High-order quantum coherence in the spatial domain plays a crucial role in a variety of applications, such as quantum imaging, holography, and microscopy. However, the active control of second-order spatial quantum coherence remains a challenging task. Here we predict theoretically and demonstrate experimentally the first active manipulation of second-order spatial quantum coherence,which exhibits the capability of switching between bunching and anti-bunching, by mapping the entanglement of spatially structured photons. We also show that signal processing based on quantum coherence exhibits robust resistance to intensity disturbance. Our findings not only enhance existing applications but also pave the way for broader utilization of higher-order spatial quantum coherence. 展开更多
关键词 PARTICLES QUANTUM spatially
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Delayed neurological dysfunction following posterior laminectomy with lateral mass screw fixation:A case report and review of literature
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作者 Rui-Zhong Yan chao chen +6 位作者 Chu-Ran Lin Yan-Hui Wei Zhi-Jian Guo Ya-Kun Li Quan Zhang He-Yi Shen Hao-Lin Sun 《World Journal of Clinical Cases》 SCIE 2024年第7期1356-1364,共9页
BACKGROUND While most complications of cervical surgery are reversible,some,such as symptomatic postoperative spinal epidural hematoma(SEH),which generally occurs within 24 h,are associated with increased morbidity an... BACKGROUND While most complications of cervical surgery are reversible,some,such as symptomatic postoperative spinal epidural hematoma(SEH),which generally occurs within 24 h,are associated with increased morbidity and mortality.Delayed neurological dysfunction is diagnosed in cases when symptoms present>3 d postoperatively.Owing to its rarity,the risk factors for delayed neurological dysfunction are unclear.Consequently,this condition can result in irreversible neurological deficits and serious consequences.In this paper,we present a case of postoperative SEH that developed three days after hematoma evacuation.CASE SUMMARY A 68-year-old man with an American Spinal Injury Association(ASIA)grade C injury was admitted to our hospital with neck pain and tetraplegia following a fall.The C3-C7 posterior laminectomy and the lateral mass screw fixation surgery were performed on the tenth day.Postoperatively,the patient showed no changes in muscle strength or ASIA grade.The patient experienced neck pain and subcutaneous swelling on the third day postoperatively,his muscle strength decreased,and his ASIA score was grade A.Magnetic resonance imaging showed hypointense signals on T1 weighted image(T1WI)and T2WI located behind the epidural space,with spinal cord compression.Emergency surgical intervention for the hematoma was performed 12 h after onset.Although hypoproteinemia and pleural effusion did not improve in the perioperative period,the patient recovered to ASIA grade C on day 30 after surgery,and was transferred to a functional rehabilitation exercise unit.CONCLUSION This case shows that amelioration of low blood albumin and pleural effusion is an important aspect of the perioperative management of cervical surgery.Surgery to relieve the pressure on the spinal cord should be performed as soon as possible to decrease neurological disabilities. 展开更多
关键词 Delayed postoperative spinal epidural hematoma Complications Spinal surgery HYPOPROTEINEMIA Risk factor Case report
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鼻咽癌组织F-box/WD重复结构域7、细胞因子信号抑制因子1表达及其临床意义
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作者 陈润 蔡小慧 +7 位作者 曾春雨 郭珊 郭小琼 平亚楠 晁晨 谢少如 何书情 陈婷娟 《东南大学学报(医学版)》 CAS 2024年第6期821-828,共8页
目的:探讨鼻咽癌(NPC)组织中F-box/WD重复结构域7(FBXW7)、细胞因子信号抑制因子1(SOCS1)的表达水平及其临床意义。方法:选取本院2018年5月至2020年5月期间住院的100例NPC患者作为研究对象,采集病理活检癌组织标本,同时收集患者临床特... 目的:探讨鼻咽癌(NPC)组织中F-box/WD重复结构域7(FBXW7)、细胞因子信号抑制因子1(SOCS1)的表达水平及其临床意义。方法:选取本院2018年5月至2020年5月期间住院的100例NPC患者作为研究对象,采集病理活检癌组织标本,同时收集患者临床特征资料;另选取32例慢性鼻咽炎患者作为对照组。采用免疫组织化学染色和蛋白质印迹法检测组织中FBXW7、SOCS1的表达情况,并进一步分析FBXW7、SOCS1表达水平与临床病理特征的关系;绘制乘积极限法(Kaplan-Meier)曲线分析FBXW7、SOCS1表达对患者预后生存率的影响;比例风险回归模型(Cox)回归分析影响NPC患者预后死亡的风险因素。结果:NPC组FBXW7、SOCS1阳性表达率明显低于对照组(χ^(2)值分别为23.871、28.969,P<0.001);FBXW7阳性表达患者3年生存率明显高于阴性表达患者(84.38%vs 54.41%,P=0.002),SOCS1阳性表达患者3年生存率明显高于阴性表达患者(93.94%vs 49.25%,P<0.001);FBXW7和SOCS1阴性表达是NPC患者死亡的危险因素(P<0.05)。结论:在NPC患者组织中FBXW7和SOCS1阳性表达率较低,二者表达与NPC患者预后密切相关。 展开更多
关键词 鼻咽癌 F-box/WD重复结构域7 细胞因子信号抑制因子1 预后
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Dynamic changes and clinical value of lipocalin 2 in liver diseases caused by microbial infections
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作者 Feng chen Shan-Shan Wu +1 位作者 chao chen cheng Zhou 《World Journal of Hepatology》 2024年第2期177-185,共9页
Lipocalin 2(LCN2)plays a pivotal role in iron metabolism,particularly in the context of microbial infection resistance(e.g.,viruses,bacteria,parasites,etc.).LCN2 combats microbial infection by directly assisting the b... Lipocalin 2(LCN2)plays a pivotal role in iron metabolism,particularly in the context of microbial infection resistance(e.g.,viruses,bacteria,parasites,etc.).LCN2 combats microbial infection by directly assisting the body in competing with microorganisms for iron,inducing immune cells to secrete various cytokines to enhance systemic immune responses,or recruiting neutrophils to infectious sites.The liver serves as the primary organ for LCN2 secretion during microbial infections.This review encapsulates recent advances in dynamic changes,clinical values,and the effects of LCN2 in infectious liver diseases caused by various microbial microorganisms. 展开更多
关键词 Lipocalin 2 Microbial infection IMMUNITY Liver diseases
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2023年新高考全国Ⅰ卷第21题源流探析
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作者 陈超 《河北理科教学研究》 2024年第3期56-59,64,共5页
2023年新高考全国Ⅰ卷第21题是具有数列递推关系背景的概率问题,此类试题也是近些年高考的热点,考查全概率公式、概率的乘法、加法公式,属于概率与数列的综合问题,对学生理性思维、数学应用能力和数学抽象、逻辑推理、数学运算核心素养... 2023年新高考全国Ⅰ卷第21题是具有数列递推关系背景的概率问题,此类试题也是近些年高考的热点,考查全概率公式、概率的乘法、加法公式,属于概率与数列的综合问题,对学生理性思维、数学应用能力和数学抽象、逻辑推理、数学运算核心素养的要求较高.文章从教材之源、真题之源、赛题之源、文献之源等角度探析此题的源流,总结出此类概率数列综合问题中递推关系的类型和解题思路,并给出针对性的教学建议. 展开更多
关键词 高考试题 数列递推关系 概率数列综合问题 试题源流
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蓝激光成像技术微放大分型对慢性胃炎萎缩性病灶的诊断价值 被引量:4
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作者 陈超 汪涛 +6 位作者 刘文祥 张宁宁 黄福秀 梁志民 徐衍 赵慧 殷健 《中国内镜杂志》 2022年第8期59-64,共6页
目的评估蓝激光成像技术(BLI)微放大分型对慢性胃炎萎缩性病灶的诊断价值。方法2017年12月-2019年6月随机对解放军总医院第四医学中心420例慢性胃炎患者使用BLI微放大检查(放大40~60倍),计算其诊断慢性胃炎萎缩性病灶的敏感度、特异度... 目的评估蓝激光成像技术(BLI)微放大分型对慢性胃炎萎缩性病灶的诊断价值。方法2017年12月-2019年6月随机对解放军总医院第四医学中心420例慢性胃炎患者使用BLI微放大检查(放大40~60倍),计算其诊断慢性胃炎萎缩性病灶的敏感度、特异度、阳性预测值和阴性预测值,评估其诊断价值。结果共发现慢性萎缩性胃炎231例,非萎缩性胃炎189例。共活检822处病灶。其中,萎缩性病灶376处,非萎缩性病灶446处;根据团队以往经验,将慢性胃炎BLI微放大分为四型:菊花绒毛型(共106处)、结节绒毛型(共203处)、鱼鳞型(共20处)和规则型(共493处)。106处菊花绒毛型病灶中,萎缩性病灶88处,非萎缩性病灶18处,诊断萎缩性病灶的阳性预测值为83.0%(88/106);203处结节绒毛型病灶中,萎缩性病灶170处,非萎缩性病灶33处,诊断萎缩性病灶的阳性预测值为83.7%(170/203);20处鱼鳞型病灶中,萎缩性病灶18处,非萎缩性病灶2处,诊断萎缩性病灶的阳性预测值为90.0%(18/20);493处规则型病灶中,萎缩性病灶100处,非萎缩性病灶393处,诊断非萎缩性病灶的阳性预测值为79.7%(393/493)。菊花绒毛型、结节绒毛型和鱼鳞型三型联合诊断萎缩性病灶的敏感度为73.4%,特异度为88.1%,阳性预测值为83.9%,阴性预测值为79.7%,准确度为81.4%,诊断中重度萎缩性病灶的敏感度可提升至85.7%。结论BLI微放大分型有助于提高慢性胃炎萎缩性病灶的内镜识别度及诊断率,尤其是中重度萎缩性病灶。 展开更多
关键词 慢性萎缩性胃炎 肠上皮化生 内镜检查 蓝激光成像技术 微放大 诊断
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A Study on Effective Strategies for Improving English Writing and Teaching to College Students
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作者 chao chen Nurul Ajleaa Abdul Rahman +1 位作者 Goh Ying Soon Nurul Ain Chua 《Journal of Educational Theory and Management》 2024年第4期65-68,共4页
This paper studies how to effectively improve the English writing skills of college students.It introduces the importance of English writing skills and the current situation,and finds that college students generally h... This paper studies how to effectively improve the English writing skills of college students.It introduces the importance of English writing skills and the current situation,and finds that college students generally have problems such as insufficient vocabulary and frequent grammatical errors;it analyses the advantages and disadvantages of traditional and modern teaching methods,with the traditional method focusing too much on the form,while the modern method may neglect the consolidation of basic knowledge and personalized needs.Effective strategies for university students are proposed,including classroom teaching,personalised instruction and practical activities.In classroom teaching,writing tasks with practical application scenarios are designed and diversified teaching methods are used.In personalised instruction,students’needs are understood and targeted instruction is provided.In practical activities,diverse writing tasks are designed and effective feedback mechanisms are established.Finally,the contributions of the study and future research directions are summarised. 展开更多
关键词 University students English writing Teaching strategies Personalised instruction Practical activities
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对一道“不动点”试题的解析与思考
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作者 陈超 《河北理科教学研究》 2024年第4期1-4,11,共5页
通过对巴蜀中学2024届高考适应性月考(六)中一道"不动点"试题的解析与思考,介绍不动点的相关定义及性质,用例题展示不动点在高考题及模拟题中的考查、应用,以期给师生备考一些启示.
关键词 压轴题 不动点 稳定点 高考题
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