Population aging presents a growing societal challenge and imposes a heavy burden on the healthcare system in many Asian countries.Given the limited availability of formal long-term care(LTC)facilities and personnel,f...Population aging presents a growing societal challenge and imposes a heavy burden on the healthcare system in many Asian countries.Given the limited availability of formal long-term care(LTC)facilities and personnel,family caregivers play a vital role in providing care for the increasing population of older adults.While awareness of the challenges faced by caregivers is rising,discussions often remain within academic circles,resulting in the lived experiences,well-being,and needs of family caregivers being frequently overlooked.In this review,we identify four key priority areas to advance research,practice,and policy related to family caregivers in Asia:(1)Emphasizing family caregivers as sociocultural navigators in the healthcare system;(2)addressing the mental and physical health needs of family caregivers;(3)recognizing the diverse caregiving experiences across different cultural backgrounds,socioeconomic status,and countries of residence;and(4)strengthening policy support for family caregivers.Our review also identifies deficiencies in institutional LTC and underscores the importance of providing training and empowerment to caregivers.Policymakers,practitioners,and researchers interested in supporting family caregivers should prioritize these key areas to tackle the challenge of population aging in Asian countries.Cross-country knowledge exchange and capacity development are crucial for better serving both the aging population and their caregivers.展开更多
Objectives:With this study,we aimed to develop a mobile technology(mHealth)intervention to improve medication adherence among patients with coronary heart disease(CHD).Methods:The study was conducted in two phases wit...Objectives:With this study,we aimed to develop a mobile technology(mHealth)intervention to improve medication adherence among patients with coronary heart disease(CHD).Methods:The study was conducted in two phases with CHD patients from a Cardiology Department of a hospital located in China.Each phase was independent from the other.Phase 1 tested the integration of the two apps-"WeChat"and"BB Reminder"-as an mHealth intervention.All participants received the same educational materials via WeChat every two days.Participants in the experimental group received a reminder from BB Reminder for every dose of their medications.The duration of Phase 1 was 30 days for each participant.Phase 2 refined the intervention,in which educational materials were sent every five days rather than every two days,and medication-taking reminders were sent daily rather than every dose.Results:In Phase 1,an mHealth intervention was developed by integrating two mobile apps.In Phase 2,medication adherence increased at 30-day follow-up in both groups compared to baseline.At the 30-day follow-up,the mean of the decrease in medication non-adherence score in the experimental group(M=1.35,SD=2.18,n=36)was more than the decrease in control group(M=0.69,SD=1.58,n=36),which means the medication adherence improved more in the experimental group.Conclusion:The feasibility of using mHealth to remind CHD patients to take their medications is high.展开更多
Background:Although self-management approaches have shown strong evidence of positive outcomes for urinary incontinence prevention and management,few programs have been developed for Korean rural communities.Objective...Background:Although self-management approaches have shown strong evidence of positive outcomes for urinary incontinence prevention and management,few programs have been developed for Korean rural communities.Objectives:This pilot study aimed to develop,implement,and evaluate a urinary incontinence self-management program for community-dwelling women aged 55 and older with urinary incontinence in rural South Korea.Methods:This study used a one-group pre-post-test design to measure the effects of the intervention using standardized urinary incontinence symptom,knowledge,and attitude measures.Seventeen community-dwelling older women completed weekly 90-min group sessions for 5 weeks.Descriptive statistics and paired t-tests and were used to analyze data.Results:The mean of the overall interference on daily life from urine leakage(pre-test:M=5.76±2.68,post-test:M=2.29±1.93,t=4.609,p<0.001)and the sum of International Consultation on Incontinence Questionnaire scores(pre-test:M=11.59±3.00,post-test:M=5.29±3.02,t=-5.881,p<0.001)indicated significant improvement after the intervention.Improvement was also noted on the mean knowledge(pre-test:M=19.07±3.34,post-test:M=23.15±2.60,t=7.550,p<0.001)and attitude scores(pre-test:M=2.64±0.19,post-test:M=3.08±0.41,t=5.150,p<0.001).Weekly assignments were completed 82.4%of the time.Participants showed a high satisfaction level(M=26.82±1.74,range 22e28)with the group program.Conclusions:Implementation of a urinary incontinence self-management program was accompanied by improved outcomes for Korean older women living in rural communities who have scarce resources for urinary incontinence management and treatment.Urinary incontinence self-management education approaches have potential for widespread implementation in nursing practice.展开更多
Objective:This study aims to evaluate the effects of a symptom management intervention(SMI)based on symptom management group sessions combined with a mobile health(mHealth)application(app)on the knowledge of symptom m...Objective:This study aims to evaluate the effects of a symptom management intervention(SMI)based on symptom management group sessions combined with a mobile health(mHealth)application(app)on the knowledge of symptom management,the certainty of symptom self-management,symptom severity,symptom distress,medication adherence,social support,and quality of life among persons living with HIV(PLWH)in China.Methods:A parallel randomized controlled trial with 61 PLWH was conducted in Shanghai,China.The participants in the control group(n¼30)downloaded the Symptom Management(SM)app according to their needs and preferences,and received routine follow-ups.The participants in the intervention group(n¼31)were guided to download and use the SM app,and received four tailored weekly group sessions at routine follow-ups.Each group session lasted for approximately 2 h and targeted one of the major modules of the SM app.All the outcomes were assessed at baseline and post-intervention.The study was registered with the Chinese Clinical Trial Registry(ChiCTR1900024821).Results:The symptom management knowledge and certainty of symptom self-management were significantly improved after the intervention(all P<0.01).Compared with the control group,the scores of symptoms reasons knowledge score improved 11.47 points(95%CI:3.41,19.53)and scores of symptoms self-management knowledge score improved 12.80 points(95%CI:4.55,21.05)in the intervention group after controlling for covariates.However,other outcomes did not show statistically significant differences between the intervention group and the control group(P>0.05).Conclusion:The SMI could improve PLWH’s symptom management knowledge and certainty of symptom self-management.Multi-center studies with larger sample sizes and longer follow-ups are needed to further understand the effects of SM app on ameliorating symptom severity and symptom distress.More innovative strategies are also needed to promote and maintain the sustainability of the SM app.展开更多
Super-resolution imaging with superlens has been one of the fundamental research topics. Unfortunately, the resolution of superlens is inevitably restrained by material loss. To address the problem, we introduce the s...Super-resolution imaging with superlens has been one of the fundamental research topics. Unfortunately, the resolution of superlens is inevitably restrained by material loss. To address the problem, we introduce the solid immersion mechanism into the slab superlens and the cylindrical superlens. The proposed solid immersion slab superlens(SISSL) and the solid immersion cylindrical superlens(SICSL) can improve the resolution by converting evanescent wave to propagating wave using high refractive index materials. From the perspective of applications, the cylindrical superlens with finite cross section and the ability of magnification or demagnification has more advantages than the slab superlens. Therefore,we focus on demonstrating analytically the super-resolution imaging of SICSL. Due to the impedance mismatching caused by solid immersion mechanism, the whispering gallery modes(WGMs) are excited between SICSL and the air interface.We clarify the excitation conditions of WGMs and analyze their influence on the imaging quality of SICSL. The SISSL and SICSL may pave a way to apply in lithography technique and real-time biomolecular imaging in future.展开更多
The need for institutional long-term care(LTC)services,including nursing homes(NHs),is increasing in China's Mainland in part due to the aging population and changing family structures.In developing NH staff train...The need for institutional long-term care(LTC)services,including nursing homes(NHs),is increasing in China's Mainland in part due to the aging population and changing family structures.In developing NH staff training programs,a review is needed to synthesize knowledge about staff and resident characteristics,and care provided in NHs.This systematic review aims to describe,in Chinese NHs,(1)NH staff characteristics and the care they provide,(2)resident characteristics and care needs,and (3)the role of family members.The 45 articles included in this review covered both urban and rural areas of China's Mainland.We found that staff in Chinese NHs were older and had lower education levels in comparison with those in western countries.Most direct caregivers in urban areas were migratory workers from rural area.Chinese NHs had few qualification standards for staff preparation for their roles in NHs.Also,functional levels of residents in Chinese NHs were higher compared to NH residents in western countries.In addition,family members played important roles in caring for NH residents.These findings suggest a need for staff development programs that tailor for lower educated NH staff and care needs of residents with widely varying levels in function from independent to bedbound in China's Mainland.The findings also suggest that staff qualification standards require critically policy development to improve the capacity of Chinese NHs to provide competent and safe care.展开更多
Aim:As conflict caused by cultural diversity among patients in China continues to rise,hospitals are in urgent need for improvement of transcultural efficacy among nurses.This study aims to evaluate the transcultural ...Aim:As conflict caused by cultural diversity among patients in China continues to rise,hospitals are in urgent need for improvement of transcultural efficacy among nurses.This study aims to evaluate the transcultural self-efficacy of nurses working in the tertiary general hospital in Guizhou Province,an ethnic minority region in western China,and to identify whether nurses'demographic characteristics affect their transcultural self-efficacy.Method:We used the Chinese version of the Transcultural Self-Efficacy Tool(TSET-CV)to survey 1,190 inservice nurses.Results:Results showed that the level of transcultural self-efficacy of the nurses was generally moderate;few of the nurses had high or low transcultural self-efficacy.The nurses'transcultural self-efficacy was affected by demographic variables,including age,marital status,employment type,income,work experience,and whether or not they were head nurses.Having a stable work environment,a stable marriage,a good educational background,and a high-ranked professional title were associated with increased transcultural self-efficacy.Conclusion:Nursing administrators in hospitals should offer continuing education on transcuitural nursing according to nurses'demographic characteristics and the SEST scores.展开更多
An investigation on the soil microbe populations from an agricultural inning area at the Pearl River estuary in Guangdong province, China was conducted via high through-put sequencing. The results revealed abundant di...An investigation on the soil microbe populations from an agricultural inning area at the Pearl River estuary in Guangdong province, China was conducted via high through-put sequencing. The results revealed abundant diversity in the soil bacterial and fungal populations. In total, 197103 sequence tags were obtained from soil samples, most of which represented bacterial genera Actinomycetes, Bacillus and Marinobacter, while a majority of 118378 tags obtained were derived from fungal genera Clostridium, Devosia, Bradyrhizobium, Bdellovibrio, Phenylobacterium, Penicillium, and Emericella. Furthermore, nine physiological indexes (pH, available phosphorous, basic-group nitrogen, available potassium, catalase, sucrose, urease, phosphatase, and organic matters) were measured in three soil samples, and the association between these physiological indexes and microbe population composition was examined. The results revealed obvious inter-sample differences associated with ten dominating microbial groups: genera Clostridium, Devosia, Bradyrhizobium, Bdellovibrio, Phenylobacterium, and Penicillium were mainly impacted by pH (with a positive correlation), genera Sphingomonas and Acinetobacter mainly by available phosphorous (positive correlation), and genera Gemmatimonas and Pseudomonas by both pH and available phosphorous (negative correlation). Our study suggested that regulation of microbial species/populations might help improve soil environment to facilitate the growth of crops’ above-ground parts, and this provides practical information for inning agriculture.展开更多
Background:Migration is a fundamental demographic process that has been observed globally.It is suggested that migration is an issue of global health importance that can have an immediate and lasting impact on an indi...Background:Migration is a fundamental demographic process that has been observed globally.It is suggested that migration is an issue of global health importance that can have an immediate and lasting impact on an individual’s health and well-being.There is now an increasing body of evidence linking migration with cognitive function in older adults.In this paper,we synthesized the current evidence to develop a general conceptual framework to understand the factors contributing to the association between migration and cognitive function.Methods:A comprehensive review of the literature was conducted on the associations between migration and cognition among middle-aged and older adults.Results:Five potential mechanisms were identified from the literature:1)socioeconomic status-including education,occupation,and income;2)psychosocial factors-including social networks,social support,social stressors,and discrimination;3)behavioral factors-including smoking,drinking,and health service utilization;4)physical and psychological health status-including chronic conditions,physical function,and depression;and 5)environmental factors-including both physical and social environment.Several underlying factors were also identified-including early-life conditions,gender,and genetic factors.Conclusions:The factors linking migration and cognitive function are multidimensional and complex.This conceptual framework highlights potential implications for global health policies and planning on healthy aging and migrant health.Additional studies are needed to further examine these mechanisms to extend and refine our general conceptual framework.展开更多
Objective To investigate the effects of propofol and sevoflurane on neurological recovery of traumatic brain injury(TBI)patients in the early postoperative stage.Methods We retrospectively analyzed the clinical data o...Objective To investigate the effects of propofol and sevoflurane on neurological recovery of traumatic brain injury(TBI)patients in the early postoperative stage.Methods We retrospectively analyzed the clinical data of TBI patients who underwent craniotomy or decompressive craniectomy.Generalized additive mixed model(GAMM)was used to analyze effects of propofol and sevoflurane on Glasgow Coma Scale(GCS)on postoperative days 1,3,and 7.Multivariate regression analysis was used to analyze effects of the two anesthetics on Glasgow Outcome Scale(GOS)at discharge.Results A total of 340 TBI patients were enrolled in this study.There were 110 TBI patients who underwent craniotomy including 75 in the propofol group and 35 in the sevoflurane group,and 134 patients who underwent decompressive craniectomy including 63 in the propofol group and 71 in the sevoflurane group.It showed no significant difference in GCS at admission between the propofol and the sevoflurane groups among craniotomy patients(β=0.75,95%CI:-0.55 to 2.05,P=0.260).However,elevation in GCS from baseline was 1.73 points(95%CI:-2.81 to-0.66,P=0.002)less in the sevoflurane group than that in the propofol group on postoperative day 1,2.03 points(95%CI:-3.14 to-0.91,P 0.001)less on day 3,and 1.31 points(95%CI:-2.43 to-0.19,P=0.022)less on day 7.The risk of unfavorable GOS(GOS 1,2,and 3)at discharge was higher in the sevoflurane group(OR=4.93,95%CI:1.05 to 23.03,P=0.043).No significant difference was observed among two-group decompressive craniectomy patients in GCS and GOS.Conclusions Compared to propofol,sevoflurane was associated with worse neurological recovery during the hospital stay in TBI patients undergoing craniotomy.This difference was not detected in TBI patients undergoing decompressive craniectomy.展开更多
Total transmission plays an important role in efficiency improvement and wavefront control,and has made great progress in many applications,such as the optical film and signal transmission.Therefore,many traditional p...Total transmission plays an important role in efficiency improvement and wavefront control,and has made great progress in many applications,such as the optical film and signal transmission.Therefore,many traditional physical methods represented by transformation optics have been studied to achieve total transmission.However,these methods have strict limitations on the size of the photonic structure,and the calculation is complex.Here,we exploit deep learning to achieve this goal.In deep learning,the data-driven prediction and design are carried out by artificial neural networks(ANNs),which provide a convenient architecture for large dataset problems.By taking the transmission characteristic of the multi-layer stacks as an example,we demonstrate how optical materials can be designed by using ANNs.The trained network directly establishes the mapping from optical materials to transmission spectra,and enables the forward spectral prediction and inverse material design of total transmission in the given parameter space.Our work paves the way for the optical material design with special properties based on deep learning.展开更多
With the proliferation of mobile technologies in China,the Chinese mobile medical applications market is growing rapidly.This may be particularly useful for Chinese rural populations who have limited access to quality...With the proliferation of mobile technologies in China,the Chinese mobile medical applications market is growing rapidly.This may be particularly useful for Chinese rural populations who have limited access to quality medical care where mobile technologies can reach across geographic and socioeconomic boundaries and potentially increase access to care and improve health outcomes.展开更多
The authors regret that the clinical trial registration number appear incorrectly due to their unintentional mistake,which matched another of their clinical trial project.The correct registration number is(ChiCTR20000...The authors regret that the clinical trial registration number appear incorrectly due to their unintentional mistake,which matched another of their clinical trial project.The correct registration number is(ChiCTR2000039097).The authors would like to apologise for any inconvenience caused.展开更多
文摘Population aging presents a growing societal challenge and imposes a heavy burden on the healthcare system in many Asian countries.Given the limited availability of formal long-term care(LTC)facilities and personnel,family caregivers play a vital role in providing care for the increasing population of older adults.While awareness of the challenges faced by caregivers is rising,discussions often remain within academic circles,resulting in the lived experiences,well-being,and needs of family caregivers being frequently overlooked.In this review,we identify four key priority areas to advance research,practice,and policy related to family caregivers in Asia:(1)Emphasizing family caregivers as sociocultural navigators in the healthcare system;(2)addressing the mental and physical health needs of family caregivers;(3)recognizing the diverse caregiving experiences across different cultural backgrounds,socioeconomic status,and countries of residence;and(4)strengthening policy support for family caregivers.Our review also identifies deficiencies in institutional LTC and underscores the importance of providing training and empowerment to caregivers.Policymakers,practitioners,and researchers interested in supporting family caregivers should prioritize these key areas to tackle the challenge of population aging in Asian countries.Cross-country knowledge exchange and capacity development are crucial for better serving both the aging population and their caregivers.
基金This work was supported by the Duke University School of NursingPhD Student Pilot Study Fund+1 种基金and the Duke University Graduate SchoolInternational Dissertation Research Travel Award
文摘Objectives:With this study,we aimed to develop a mobile technology(mHealth)intervention to improve medication adherence among patients with coronary heart disease(CHD).Methods:The study was conducted in two phases with CHD patients from a Cardiology Department of a hospital located in China.Each phase was independent from the other.Phase 1 tested the integration of the two apps-"WeChat"and"BB Reminder"-as an mHealth intervention.All participants received the same educational materials via WeChat every two days.Participants in the experimental group received a reminder from BB Reminder for every dose of their medications.The duration of Phase 1 was 30 days for each participant.Phase 2 refined the intervention,in which educational materials were sent every five days rather than every two days,and medication-taking reminders were sent daily rather than every dose.Results:In Phase 1,an mHealth intervention was developed by integrating two mobile apps.In Phase 2,medication adherence increased at 30-day follow-up in both groups compared to baseline.At the 30-day follow-up,the mean of the decrease in medication non-adherence score in the experimental group(M=1.35,SD=2.18,n=36)was more than the decrease in control group(M=0.69,SD=1.58,n=36),which means the medication adherence improved more in the experimental group.Conclusion:The feasibility of using mHealth to remind CHD patients to take their medications is high.
基金This study was supported by the Mary Hester Scholarship Endowment Award of Duke University School of Nursing and by the Asian American/Pacific Islander Nurses Association's Nursing Scholarship.
文摘Background:Although self-management approaches have shown strong evidence of positive outcomes for urinary incontinence prevention and management,few programs have been developed for Korean rural communities.Objectives:This pilot study aimed to develop,implement,and evaluate a urinary incontinence self-management program for community-dwelling women aged 55 and older with urinary incontinence in rural South Korea.Methods:This study used a one-group pre-post-test design to measure the effects of the intervention using standardized urinary incontinence symptom,knowledge,and attitude measures.Seventeen community-dwelling older women completed weekly 90-min group sessions for 5 weeks.Descriptive statistics and paired t-tests and were used to analyze data.Results:The mean of the overall interference on daily life from urine leakage(pre-test:M=5.76±2.68,post-test:M=2.29±1.93,t=4.609,p<0.001)and the sum of International Consultation on Incontinence Questionnaire scores(pre-test:M=11.59±3.00,post-test:M=5.29±3.02,t=-5.881,p<0.001)indicated significant improvement after the intervention.Improvement was also noted on the mean knowledge(pre-test:M=19.07±3.34,post-test:M=23.15±2.60,t=7.550,p<0.001)and attitude scores(pre-test:M=2.64±0.19,post-test:M=3.08±0.41,t=5.150,p<0.001).Weekly assignments were completed 82.4%of the time.Participants showed a high satisfaction level(M=26.82±1.74,range 22e28)with the group program.Conclusions:Implementation of a urinary incontinence self-management program was accompanied by improved outcomes for Korean older women living in rural communities who have scarce resources for urinary incontinence management and treatment.Urinary incontinence self-management education approaches have potential for widespread implementation in nursing practice.
基金This paper is part of a project funded by the National Natural Science Foundation of China(Grant Number 71673057)the China Scholarship Council(No.201906100135).
文摘Objective:This study aims to evaluate the effects of a symptom management intervention(SMI)based on symptom management group sessions combined with a mobile health(mHealth)application(app)on the knowledge of symptom management,the certainty of symptom self-management,symptom severity,symptom distress,medication adherence,social support,and quality of life among persons living with HIV(PLWH)in China.Methods:A parallel randomized controlled trial with 61 PLWH was conducted in Shanghai,China.The participants in the control group(n¼30)downloaded the Symptom Management(SM)app according to their needs and preferences,and received routine follow-ups.The participants in the intervention group(n¼31)were guided to download and use the SM app,and received four tailored weekly group sessions at routine follow-ups.Each group session lasted for approximately 2 h and targeted one of the major modules of the SM app.All the outcomes were assessed at baseline and post-intervention.The study was registered with the Chinese Clinical Trial Registry(ChiCTR1900024821).Results:The symptom management knowledge and certainty of symptom self-management were significantly improved after the intervention(all P<0.01).Compared with the control group,the scores of symptoms reasons knowledge score improved 11.47 points(95%CI:3.41,19.53)and scores of symptoms self-management knowledge score improved 12.80 points(95%CI:4.55,21.05)in the intervention group after controlling for covariates.However,other outcomes did not show statistically significant differences between the intervention group and the control group(P>0.05).Conclusion:The SMI could improve PLWH’s symptom management knowledge and certainty of symptom self-management.Multi-center studies with larger sample sizes and longer follow-ups are needed to further understand the effects of SM app on ameliorating symptom severity and symptom distress.More innovative strategies are also needed to promote and maintain the sustainability of the SM app.
基金Project supported by the National Key Research and Development Program of China (Grant No. 2020YFA0710100)the National Natural Science Foundation of China (Grant Nos. 92050102 and 11874311)the Fundamental Research Funds for the Central Universities (Grant Nos. 20720220033 and 20720200074)。
文摘Super-resolution imaging with superlens has been one of the fundamental research topics. Unfortunately, the resolution of superlens is inevitably restrained by material loss. To address the problem, we introduce the solid immersion mechanism into the slab superlens and the cylindrical superlens. The proposed solid immersion slab superlens(SISSL) and the solid immersion cylindrical superlens(SICSL) can improve the resolution by converting evanescent wave to propagating wave using high refractive index materials. From the perspective of applications, the cylindrical superlens with finite cross section and the ability of magnification or demagnification has more advantages than the slab superlens. Therefore,we focus on demonstrating analytically the super-resolution imaging of SICSL. Due to the impedance mismatching caused by solid immersion mechanism, the whispering gallery modes(WGMs) are excited between SICSL and the air interface.We clarify the excitation conditions of WGMs and analyze their influence on the imaging quality of SICSL. The SISSL and SICSL may pave a way to apply in lithography technique and real-time biomolecular imaging in future.
文摘The need for institutional long-term care(LTC)services,including nursing homes(NHs),is increasing in China's Mainland in part due to the aging population and changing family structures.In developing NH staff training programs,a review is needed to synthesize knowledge about staff and resident characteristics,and care provided in NHs.This systematic review aims to describe,in Chinese NHs,(1)NH staff characteristics and the care they provide,(2)resident characteristics and care needs,and (3)the role of family members.The 45 articles included in this review covered both urban and rural areas of China's Mainland.We found that staff in Chinese NHs were older and had lower education levels in comparison with those in western countries.Most direct caregivers in urban areas were migratory workers from rural area.Chinese NHs had few qualification standards for staff preparation for their roles in NHs.Also,functional levels of residents in Chinese NHs were higher compared to NH residents in western countries.In addition,family members played important roles in caring for NH residents.These findings suggest a need for staff development programs that tailor for lower educated NH staff and care needs of residents with widely varying levels in function from independent to bedbound in China's Mainland.The findings also suggest that staff qualification standards require critically policy development to improve the capacity of Chinese NHs to provide competent and safe care.
文摘Aim:As conflict caused by cultural diversity among patients in China continues to rise,hospitals are in urgent need for improvement of transcultural efficacy among nurses.This study aims to evaluate the transcultural self-efficacy of nurses working in the tertiary general hospital in Guizhou Province,an ethnic minority region in western China,and to identify whether nurses'demographic characteristics affect their transcultural self-efficacy.Method:We used the Chinese version of the Transcultural Self-Efficacy Tool(TSET-CV)to survey 1,190 inservice nurses.Results:Results showed that the level of transcultural self-efficacy of the nurses was generally moderate;few of the nurses had high or low transcultural self-efficacy.The nurses'transcultural self-efficacy was affected by demographic variables,including age,marital status,employment type,income,work experience,and whether or not they were head nurses.Having a stable work environment,a stable marriage,a good educational background,and a high-ranked professional title were associated with increased transcultural self-efficacy.Conclusion:Nursing administrators in hospitals should offer continuing education on transcuitural nursing according to nurses'demographic characteristics and the SEST scores.
文摘An investigation on the soil microbe populations from an agricultural inning area at the Pearl River estuary in Guangdong province, China was conducted via high through-put sequencing. The results revealed abundant diversity in the soil bacterial and fungal populations. In total, 197103 sequence tags were obtained from soil samples, most of which represented bacterial genera Actinomycetes, Bacillus and Marinobacter, while a majority of 118378 tags obtained were derived from fungal genera Clostridium, Devosia, Bradyrhizobium, Bdellovibrio, Phenylobacterium, Penicillium, and Emericella. Furthermore, nine physiological indexes (pH, available phosphorous, basic-group nitrogen, available potassium, catalase, sucrose, urease, phosphatase, and organic matters) were measured in three soil samples, and the association between these physiological indexes and microbe population composition was examined. The results revealed obvious inter-sample differences associated with ten dominating microbial groups: genera Clostridium, Devosia, Bradyrhizobium, Bdellovibrio, Phenylobacterium, and Penicillium were mainly impacted by pH (with a positive correlation), genera Sphingomonas and Acinetobacter mainly by available phosphorous (positive correlation), and genera Gemmatimonas and Pseudomonas by both pH and available phosphorous (negative correlation). Our study suggested that regulation of microbial species/populations might help improve soil environment to facilitate the growth of crops’ above-ground parts, and this provides practical information for inning agriculture.
文摘Background:Migration is a fundamental demographic process that has been observed globally.It is suggested that migration is an issue of global health importance that can have an immediate and lasting impact on an individual’s health and well-being.There is now an increasing body of evidence linking migration with cognitive function in older adults.In this paper,we synthesized the current evidence to develop a general conceptual framework to understand the factors contributing to the association between migration and cognitive function.Methods:A comprehensive review of the literature was conducted on the associations between migration and cognition among middle-aged and older adults.Results:Five potential mechanisms were identified from the literature:1)socioeconomic status-including education,occupation,and income;2)psychosocial factors-including social networks,social support,social stressors,and discrimination;3)behavioral factors-including smoking,drinking,and health service utilization;4)physical and psychological health status-including chronic conditions,physical function,and depression;and 5)environmental factors-including both physical and social environment.Several underlying factors were also identified-including early-life conditions,gender,and genetic factors.Conclusions:The factors linking migration and cognitive function are multidimensional and complex.This conceptual framework highlights potential implications for global health policies and planning on healthy aging and migrant health.Additional studies are needed to further examine these mechanisms to extend and refine our general conceptual framework.
基金Beijing Natural Sciences Foundation(7173255)Beijing Municipal Administration of Hospital Incubating Program(PX2019019).
文摘Objective To investigate the effects of propofol and sevoflurane on neurological recovery of traumatic brain injury(TBI)patients in the early postoperative stage.Methods We retrospectively analyzed the clinical data of TBI patients who underwent craniotomy or decompressive craniectomy.Generalized additive mixed model(GAMM)was used to analyze effects of propofol and sevoflurane on Glasgow Coma Scale(GCS)on postoperative days 1,3,and 7.Multivariate regression analysis was used to analyze effects of the two anesthetics on Glasgow Outcome Scale(GOS)at discharge.Results A total of 340 TBI patients were enrolled in this study.There were 110 TBI patients who underwent craniotomy including 75 in the propofol group and 35 in the sevoflurane group,and 134 patients who underwent decompressive craniectomy including 63 in the propofol group and 71 in the sevoflurane group.It showed no significant difference in GCS at admission between the propofol and the sevoflurane groups among craniotomy patients(β=0.75,95%CI:-0.55 to 2.05,P=0.260).However,elevation in GCS from baseline was 1.73 points(95%CI:-2.81 to-0.66,P=0.002)less in the sevoflurane group than that in the propofol group on postoperative day 1,2.03 points(95%CI:-3.14 to-0.91,P 0.001)less on day 3,and 1.31 points(95%CI:-2.43 to-0.19,P=0.022)less on day 7.The risk of unfavorable GOS(GOS 1,2,and 3)at discharge was higher in the sevoflurane group(OR=4.93,95%CI:1.05 to 23.03,P=0.043).No significant difference was observed among two-group decompressive craniectomy patients in GCS and GOS.Conclusions Compared to propofol,sevoflurane was associated with worse neurological recovery during the hospital stay in TBI patients undergoing craniotomy.This difference was not detected in TBI patients undergoing decompressive craniectomy.
基金supported by the National Key Research and Development Program of China under Grant No.2020YFA0710100the National Natural Science Foundation of China under Grants No.92050102,No.11874311,and No.11504306the Fundamental Research Funds for the Central Universities under Grant No.20720200074。
文摘Total transmission plays an important role in efficiency improvement and wavefront control,and has made great progress in many applications,such as the optical film and signal transmission.Therefore,many traditional physical methods represented by transformation optics have been studied to achieve total transmission.However,these methods have strict limitations on the size of the photonic structure,and the calculation is complex.Here,we exploit deep learning to achieve this goal.In deep learning,the data-driven prediction and design are carried out by artificial neural networks(ANNs),which provide a convenient architecture for large dataset problems.By taking the transmission characteristic of the multi-layer stacks as an example,we demonstrate how optical materials can be designed by using ANNs.The trained network directly establishes the mapping from optical materials to transmission spectra,and enables the forward spectral prediction and inverse material design of total transmission in the given parameter space.Our work paves the way for the optical material design with special properties based on deep learning.
文摘With the proliferation of mobile technologies in China,the Chinese mobile medical applications market is growing rapidly.This may be particularly useful for Chinese rural populations who have limited access to quality medical care where mobile technologies can reach across geographic and socioeconomic boundaries and potentially increase access to care and improve health outcomes.
文摘The authors regret that the clinical trial registration number appear incorrectly due to their unintentional mistake,which matched another of their clinical trial project.The correct registration number is(ChiCTR2000039097).The authors would like to apologise for any inconvenience caused.
