加速康复外科(enhanced recovery after surgery,ERAS)是指采用有循证医学证据的一系列多模式围术期优化措施,以阻断或减轻机体应激反应为目的,最终促进患者术后尽快康复。目前,ERAS已经在胃肠道手术、泌尿系统手术、胰腺手术、妇产科...加速康复外科(enhanced recovery after surgery,ERAS)是指采用有循证医学证据的一系列多模式围术期优化措施,以阻断或减轻机体应激反应为目的,最终促进患者术后尽快康复。目前,ERAS已经在胃肠道手术、泌尿系统手术、胰腺手术、妇产科手术、减重手术等多种手术类型中广泛应用,其效果已经被越来越多的研究结果证实。近年来ERAS理念成为推动围术期多学科协作管理的核心,其在围术期疼痛管理中的作用也越来越突出。随着ERAS的发展,麻醉医学也逐渐向围术期医学转变。ERAS强调多学科合作,麻醉医师在术前评估优化、围术期管理及改善患者远期预后方面,均起到了至关重要的作用。展开更多
Objective To investigate the efficacy and safety of continuous local anesthetic wound infiltration following open abdominal partial hepatectomy. Methods We performed a prospective, non-randomized, concurrent and con...Objective To investigate the efficacy and safety of continuous local anesthetic wound infiltration following open abdominal partial hepatectomy. Methods We performed a prospective, non-randomized, concurrent and controlled study. Patients undergoing open abdominal partial hepatectomy, according to their willingness, accepted one of the following managements for the postoperative pain： continuous wound catheter （CWC） infiltration, patient-controlled epidural analgesia （PCEA）, patient-controlled intravenous analgesia of morphine （PCIAM）, and patient-controlled intravenous analgesia of sufentanil （PCIAS）. The primary outcome was postoperative visual analogue scale （VAS） scores at rest and on movement. Secondary outcomes included consumption of rescue medication, side effects, and complications associated with postoperative pain management. Results From August 2013 to December 2013, 80 patients were allocated to receive CWC （n=10）, PCEA （n=22）, PCIAM （n=29）, or PCIAS （n=19）. After adjusting for age, sex, body mass index, percentage of resected liver, operation time, and Amsterdam Preoperative Anxiety and Information Scale, there was no significant difference in the VAS scores at rest or on movement between Group CWC and the other groups, namely PCEA, PCIAM, and PCIAS, at 4, 12, 48, and 72 hours postoperatively （all P〉0.05）. The need for rescue medication was not significantly different between Group CWC and the other three groups at 48 and 72 hours postoperatively （all P〉0.05）. There was no significant difference in the incidence of postoperative nausea and vomiting or anal exsufflation time between group CWC and the other three groups （all P〉0.05）. No severe adverse effects associated with continuous wound infiltration were observed during the study period. Conclusions CWC has a comparable analgesic effect compared with traditional analgesia methods at most time points postoperatively. CWC is a safe alternative for the postoperative analgesic management of open liver surgery.展开更多
文摘加速康复外科(enhanced recovery after surgery,ERAS)是指采用有循证医学证据的一系列多模式围术期优化措施,以阻断或减轻机体应激反应为目的,最终促进患者术后尽快康复。目前,ERAS已经在胃肠道手术、泌尿系统手术、胰腺手术、妇产科手术、减重手术等多种手术类型中广泛应用,其效果已经被越来越多的研究结果证实。近年来ERAS理念成为推动围术期多学科协作管理的核心,其在围术期疼痛管理中的作用也越来越突出。随着ERAS的发展,麻醉医学也逐渐向围术期医学转变。ERAS强调多学科合作,麻醉医师在术前评估优化、围术期管理及改善患者远期预后方面,均起到了至关重要的作用。
文摘Objective To investigate the efficacy and safety of continuous local anesthetic wound infiltration following open abdominal partial hepatectomy. Methods We performed a prospective, non-randomized, concurrent and controlled study. Patients undergoing open abdominal partial hepatectomy, according to their willingness, accepted one of the following managements for the postoperative pain： continuous wound catheter （CWC） infiltration, patient-controlled epidural analgesia （PCEA）, patient-controlled intravenous analgesia of morphine （PCIAM）, and patient-controlled intravenous analgesia of sufentanil （PCIAS）. The primary outcome was postoperative visual analogue scale （VAS） scores at rest and on movement. Secondary outcomes included consumption of rescue medication, side effects, and complications associated with postoperative pain management. Results From August 2013 to December 2013, 80 patients were allocated to receive CWC （n=10）, PCEA （n=22）, PCIAM （n=29）, or PCIAS （n=19）. After adjusting for age, sex, body mass index, percentage of resected liver, operation time, and Amsterdam Preoperative Anxiety and Information Scale, there was no significant difference in the VAS scores at rest or on movement between Group CWC and the other groups, namely PCEA, PCIAM, and PCIAS, at 4, 12, 48, and 72 hours postoperatively （all P〉0.05）. The need for rescue medication was not significantly different between Group CWC and the other three groups at 48 and 72 hours postoperatively （all P〉0.05）. There was no significant difference in the incidence of postoperative nausea and vomiting or anal exsufflation time between group CWC and the other three groups （all P〉0.05）. No severe adverse effects associated with continuous wound infiltration were observed during the study period. Conclusions CWC has a comparable analgesic effect compared with traditional analgesia methods at most time points postoperatively. CWC is a safe alternative for the postoperative analgesic management of open liver surgery.
