目的:采用数据挖掘技术,探索分析王作顺教授治疗湿疹的临床用药规律,总结王作顺教授治疗湿疹的经验。方法:收集2020年5月至2023年12月期间天津市中医药研究院附属医院王作顺教授门诊诊断为湿疹的患者处方信息,在规范整理后,利用Microsof...目的:采用数据挖掘技术,探索分析王作顺教授治疗湿疹的临床用药规律,总结王作顺教授治疗湿疹的经验。方法:收集2020年5月至2023年12月期间天津市中医药研究院附属医院王作顺教授门诊诊断为湿疹的患者处方信息,在规范整理后,利用Microsoft Excel2019、SPSS Statistic21.0、SPSSModeler18.0等计算机软件建立数据库并进行用药频次等统计、关联规则分析、聚类分析。结果:纳入研究的处方273张,共涉及中药135味,排名前12位的药物分别为甘草、白鲜皮、地肤子、黄芩、白术、干姜、法半夏、黄连、蒺藜、薏苡仁、川芎、当归,关联分析结果提示生成“甘草–白鲜皮、甘草–地肤子”等9对2味药物关联;聚类分析出现“法半夏、黄连、黄芩、干姜、白鲜皮、地肤子、甘草、白术”、“防风、牡丹皮、蒺藜、薏苡仁、土茯苓”等4个聚类方;结论:王作顺教授治疗湿疹时尤其重视脾胃,以平调脾胃寒热、清除皮肤湿毒、疏散皮肤风邪为主要治法。Objective: To explore and analyze the clinical medication patterns used by Professor Wang Zuoshun in treating eczema through data mining techniques and summarize his experience in treating eczema. Methods: Prescription information of patients diagnosed with eczema in Professor Wang Zuoshun’s outpatient clinic at the Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine from May 2020 to December 2023 was collected. After standardized organization, databases were established using Microsoft Excel2019, SPSS Statistic21.0, and SPSS Modeler18.0 software for statistical analysis of medication frequency, association rule analysis, and cluster analysis. Results: A total of 273 prescriptions were included in the study, involving 135 Chinese herbs. The top 12 herbs were Glycyrrhizae Radix (Gancao), Cortex Dictamni (Baixianpi), Kochiae Fructus (Difuzi), Scutellariae Radix (Huangqin), Atractylodis Macrocephalae Rhizoma (Baizhu), Zingiberis Rhizoma (Ganjiang), Pinelliae Rhizoma Praeparatum (Fabanxia), Coptidis Rhizoma (Huanglian), Tribuli Fructus (Jili), Coicis Semen (Yiyiren), Chuanxiong Rhizoma (Chuanxiong), and Angelicae Sinensis Radix (Danggui). The association analysis identified nine pairs of two-herb associations, such as “Glycyrrhizae Radix-Cortex Dictamni” and “Glycyrrhizae Radix-Kochiae Fructus”. Cluster analysis revealed four clusters of herbal formulas, including “Pinelliae Rhizoma Praeparatum, Coptidis Rhizoma, Scutellariae Radix, Zingiberis Rhizoma, Cortex Dictamni, Kochiae Fructus, Glycyrrhizae Radix, Atractylodis Macrocephalae Rhizoma” and “Saposhnikoviae Radix, Moutan Cortex, Tribuli Fructus, Coicis Semen, Smilacis Glabrae Rhizoma”. Conclusion: Professor Wang Zuoshun emphasizes the importance of the spleen and stomach in treating eczema, focusing on regulating the spleen and stomach’s heat and cold, eliminating dampness and toxicity from the skin, and dispersing wind pathogens in the skin as the main therapeutic approaches.展开更多
介绍王作顺教授以经方为主辨证治疗上热下寒病证的临床经验。上热下寒证属寒热错杂的复杂临床证候,其基本病机为人体阴阳气机升降失常。王作顺教授认为,现代人由于饮食不节、起居失常、精神压力等各种因素而常见上热下寒体质,并在临床...介绍王作顺教授以经方为主辨证治疗上热下寒病证的临床经验。上热下寒证属寒热错杂的复杂临床证候,其基本病机为人体阴阳气机升降失常。王作顺教授认为,现代人由于饮食不节、起居失常、精神压力等各种因素而常见上热下寒体质,并在临床辨证中擅长运用乌梅丸、柴胡桂枝干姜汤等经方加减化裁,运用平调寒热之法加以治疗,使机体达阴平阳秘之态而获痊愈。This article introduces Professor Wang Zuoshun’s clinical experience in treating upper heat and lower cold syndrome, a complex clinical condition characterized by mixed cold and heat, primarily with classical formulas based on syndrome differentiation. The fundamental pathogenesis of this syndrome involves the imbalance of ascending and descending movements of Yin and Yang qi in the human body. Professor Wang Zuoshun believes that modern individuals commonly exhibit an upper heat and lower cold constitution due to various factors such as improper diet, irregular lifestyle, and mental stress. In clinical syndrome differentiation, he excels at using modified versions of classical formulas such as Wumei Pill and Chaihu Guizhi Ganjiang Decoction, employing methods to harmonize cold and heat, thereby restoring the body to a state of balanced Yin and Yang and achieving recovery.展开更多
文摘目的:采用数据挖掘技术,探索分析王作顺教授治疗湿疹的临床用药规律,总结王作顺教授治疗湿疹的经验。方法:收集2020年5月至2023年12月期间天津市中医药研究院附属医院王作顺教授门诊诊断为湿疹的患者处方信息,在规范整理后,利用Microsoft Excel2019、SPSS Statistic21.0、SPSSModeler18.0等计算机软件建立数据库并进行用药频次等统计、关联规则分析、聚类分析。结果:纳入研究的处方273张,共涉及中药135味,排名前12位的药物分别为甘草、白鲜皮、地肤子、黄芩、白术、干姜、法半夏、黄连、蒺藜、薏苡仁、川芎、当归,关联分析结果提示生成“甘草–白鲜皮、甘草–地肤子”等9对2味药物关联;聚类分析出现“法半夏、黄连、黄芩、干姜、白鲜皮、地肤子、甘草、白术”、“防风、牡丹皮、蒺藜、薏苡仁、土茯苓”等4个聚类方;结论:王作顺教授治疗湿疹时尤其重视脾胃,以平调脾胃寒热、清除皮肤湿毒、疏散皮肤风邪为主要治法。Objective: To explore and analyze the clinical medication patterns used by Professor Wang Zuoshun in treating eczema through data mining techniques and summarize his experience in treating eczema. Methods: Prescription information of patients diagnosed with eczema in Professor Wang Zuoshun’s outpatient clinic at the Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine from May 2020 to December 2023 was collected. After standardized organization, databases were established using Microsoft Excel2019, SPSS Statistic21.0, and SPSS Modeler18.0 software for statistical analysis of medication frequency, association rule analysis, and cluster analysis. Results: A total of 273 prescriptions were included in the study, involving 135 Chinese herbs. The top 12 herbs were Glycyrrhizae Radix (Gancao), Cortex Dictamni (Baixianpi), Kochiae Fructus (Difuzi), Scutellariae Radix (Huangqin), Atractylodis Macrocephalae Rhizoma (Baizhu), Zingiberis Rhizoma (Ganjiang), Pinelliae Rhizoma Praeparatum (Fabanxia), Coptidis Rhizoma (Huanglian), Tribuli Fructus (Jili), Coicis Semen (Yiyiren), Chuanxiong Rhizoma (Chuanxiong), and Angelicae Sinensis Radix (Danggui). The association analysis identified nine pairs of two-herb associations, such as “Glycyrrhizae Radix-Cortex Dictamni” and “Glycyrrhizae Radix-Kochiae Fructus”. Cluster analysis revealed four clusters of herbal formulas, including “Pinelliae Rhizoma Praeparatum, Coptidis Rhizoma, Scutellariae Radix, Zingiberis Rhizoma, Cortex Dictamni, Kochiae Fructus, Glycyrrhizae Radix, Atractylodis Macrocephalae Rhizoma” and “Saposhnikoviae Radix, Moutan Cortex, Tribuli Fructus, Coicis Semen, Smilacis Glabrae Rhizoma”. Conclusion: Professor Wang Zuoshun emphasizes the importance of the spleen and stomach in treating eczema, focusing on regulating the spleen and stomach’s heat and cold, eliminating dampness and toxicity from the skin, and dispersing wind pathogens in the skin as the main therapeutic approaches.
文摘介绍王作顺教授以经方为主辨证治疗上热下寒病证的临床经验。上热下寒证属寒热错杂的复杂临床证候,其基本病机为人体阴阳气机升降失常。王作顺教授认为,现代人由于饮食不节、起居失常、精神压力等各种因素而常见上热下寒体质,并在临床辨证中擅长运用乌梅丸、柴胡桂枝干姜汤等经方加减化裁,运用平调寒热之法加以治疗,使机体达阴平阳秘之态而获痊愈。This article introduces Professor Wang Zuoshun’s clinical experience in treating upper heat and lower cold syndrome, a complex clinical condition characterized by mixed cold and heat, primarily with classical formulas based on syndrome differentiation. The fundamental pathogenesis of this syndrome involves the imbalance of ascending and descending movements of Yin and Yang qi in the human body. Professor Wang Zuoshun believes that modern individuals commonly exhibit an upper heat and lower cold constitution due to various factors such as improper diet, irregular lifestyle, and mental stress. In clinical syndrome differentiation, he excels at using modified versions of classical formulas such as Wumei Pill and Chaihu Guizhi Ganjiang Decoction, employing methods to harmonize cold and heat, thereby restoring the body to a state of balanced Yin and Yang and achieving recovery.
