A flashing ratchet model of a two-headed molecular motor in a two-dimensional potential is proposed to simulate the hand-over-hand motion of kinesins. Extensive Langevin simulations of the model are performed. We disc...A flashing ratchet model of a two-headed molecular motor in a two-dimensional potential is proposed to simulate the hand-over-hand motion of kinesins. Extensive Langevin simulations of the model are performed. We discuss the dependences of motion and efficiency on the model parameters, including the external force and the temperature. A good qualitative agreement with the expected behavior is observed.展开更多
In this paper, we present a model of the Brownian motor in a feedback controlled ratchet, in which the application of the flashing potential depends on the state of the particle to be controlled. We derive an analytic...In this paper, we present a model of the Brownian motor in a feedback controlled ratchet, in which the application of the flashing potential depends on the state of the particle to be controlled. We derive an analytical expression for the velocity induced by the feedback ratchet, which is a function of several parameters, including the ratio of the two switching temperatures and the asymmetry parameter of the potential field. The motor shows a current inversion when either parameter is varied.展开更多
基金Project supported by the Educational Commission of Henan Province,China (Grant No. 2006140015)the Science and Technology Planning Project of Henan Province,China (Grant No. 092300410142)
文摘A flashing ratchet model of a two-headed molecular motor in a two-dimensional potential is proposed to simulate the hand-over-hand motion of kinesins. Extensive Langevin simulations of the model are performed. We discuss the dependences of motion and efficiency on the model parameters, including the external force and the temperature. A good qualitative agreement with the expected behavior is observed.
基金Project supported by the Educational Commission of Henan Province, China (Grant No. 2006140015)the Science and Technology Planning Project of Henan Province, China (Grant No. 092300410142)
文摘In this paper, we present a model of the Brownian motor in a feedback controlled ratchet, in which the application of the flashing potential depends on the state of the particle to be controlled. We derive an analytical expression for the velocity induced by the feedback ratchet, which is a function of several parameters, including the ratio of the two switching temperatures and the asymmetry parameter of the potential field. The motor shows a current inversion when either parameter is varied.
