前列腺癌是男性恶性肿瘤中最常见的肿瘤之一,目前根治性前列腺切除术是治疗器官局限性及局部进展期前列腺癌的最主要手段。然而在手术后部分患者会出现切缘阳性,这有可能导致前列腺癌的生化复发甚至临床进展,因此有效的治疗和预测策略...前列腺癌是男性恶性肿瘤中最常见的肿瘤之一,目前根治性前列腺切除术是治疗器官局限性及局部进展期前列腺癌的最主要手段。然而在手术后部分患者会出现切缘阳性,这有可能导致前列腺癌的生化复发甚至临床进展,因此有效的治疗和预测策略对改善患者预后至关重要。本文概述切缘阳性患者在根治前列腺切除后的最新诊治及预后,为这类病人的预防和治疗提供思路。Radical prostatectomy is the primary treatment for organ-confined and locally advanced prostate cancer, a malignancy that is one of the most frequent among men. Despite the possibility of positive surgical margins postoperatively, this may result in biochemical recurrence or even a clinical progression of prostate cancer. Therefore, effective treatment and predictive strategies are crucial for improving patient outcomes. The aim of this article is to provide an overview of the most recent progressions in diagnosing, treating, and forecasting those with positive surgical margins after radical prostatectomy, thereby offering insight into how to avert and treat them.展开更多
文摘前列腺癌是男性恶性肿瘤中最常见的肿瘤之一,目前根治性前列腺切除术是治疗器官局限性及局部进展期前列腺癌的最主要手段。然而在手术后部分患者会出现切缘阳性,这有可能导致前列腺癌的生化复发甚至临床进展,因此有效的治疗和预测策略对改善患者预后至关重要。本文概述切缘阳性患者在根治前列腺切除后的最新诊治及预后,为这类病人的预防和治疗提供思路。Radical prostatectomy is the primary treatment for organ-confined and locally advanced prostate cancer, a malignancy that is one of the most frequent among men. Despite the possibility of positive surgical margins postoperatively, this may result in biochemical recurrence or even a clinical progression of prostate cancer. Therefore, effective treatment and predictive strategies are crucial for improving patient outcomes. The aim of this article is to provide an overview of the most recent progressions in diagnosing, treating, and forecasting those with positive surgical margins after radical prostatectomy, thereby offering insight into how to avert and treat them.
