目的:评价调神润目针法结合人工泪液治疗干眼症的临床效果。方法:前瞻性选取2024年1月至2024年10月于黑龙江中医药大学附属第二医院针灸二科就诊的干眼症患者70例,采用随机数字表法分为针药组和药物组,每组35例。针药组采用调神润目针...目的:评价调神润目针法结合人工泪液治疗干眼症的临床效果。方法:前瞻性选取2024年1月至2024年10月于黑龙江中医药大学附属第二医院针灸二科就诊的干眼症患者70例,采用随机数字表法分为针药组和药物组,每组35例。针药组采用调神润目针法联合人工泪液治疗,药物组单纯使用人工泪液。疗程为每日1次,连续治疗2周。比较两组治疗前后的眼表疾病指数(OSDI)、泪膜破裂时间(BUT)、泪液分泌试验(SIT)、角膜荧光素染色(FL)及泪河高度(TMH)等指标,评估临床疗效。结果:两组患者治疗前OSDI、BUT、SIT、FL、TMH基线水平无统计学差异(P > 0.05)。治疗后两组OSDI评分均下降,且针药组显著低于药物组(P Objective: To evaluate the clinical efficacy of the Tiaoshen Runmu acupuncture method combined with artificial tears in the treatment of dry eye disease. Methods: A prospective study was conducted from January 2024 to October 2024 at the Acupuncture Department of the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, involving 70 dry eye patients. The patients were randomly divided into two groups: an acupuncture plus medication group (n = 35) and a medication-only group (n = 35). The acupuncture plus medication group received the Tiaoshen Runmu acupuncture method combined with artificial tears, while the medication-only group was treated with artificial tears alone. Treatment was administered once daily for two consecutive weeks. The Ocular Surface Disease Index (OSDI), Tear Film Breakup Time (BUT), Schirmer I Test (SIT), Fluorescein Staining (FL), and Tear Meniscus Height (TMH) were compared between the two groups to assess clinical efficacy. Results: Baseline levels of OSDI, BUT, SIT, FL, and TMH showed no significant differences between the two groups before treatment (P > 0.05). After treatment, OSDI scores in both groups decreased, with the acupuncture plus medication group showing significantly lower OSDI scores than the medication-only group (P < 0.05). BUT, SIT, FL, and TMH all improved significantly in both groups, with the acupuncture plus medication group showing greater improvements compared to the medication-only group (P < 0.05). The total clinical efficacy rate in the acupuncture plus medication group was significantly higher than that of the medication-only group (P < 0.05). Conclusion: The Tiaoshen Runmu acupuncture method combined with artificial tears is effective in improving the symptoms of dry eye disease, promoting tear secretion, and stabilizing tear film. The clinical efficacy is significantly better than artificial tears alone.展开更多
文摘目的:评价调神润目针法结合人工泪液治疗干眼症的临床效果。方法:前瞻性选取2024年1月至2024年10月于黑龙江中医药大学附属第二医院针灸二科就诊的干眼症患者70例,采用随机数字表法分为针药组和药物组,每组35例。针药组采用调神润目针法联合人工泪液治疗,药物组单纯使用人工泪液。疗程为每日1次,连续治疗2周。比较两组治疗前后的眼表疾病指数(OSDI)、泪膜破裂时间(BUT)、泪液分泌试验(SIT)、角膜荧光素染色(FL)及泪河高度(TMH)等指标,评估临床疗效。结果:两组患者治疗前OSDI、BUT、SIT、FL、TMH基线水平无统计学差异(P > 0.05)。治疗后两组OSDI评分均下降,且针药组显著低于药物组(P Objective: To evaluate the clinical efficacy of the Tiaoshen Runmu acupuncture method combined with artificial tears in the treatment of dry eye disease. Methods: A prospective study was conducted from January 2024 to October 2024 at the Acupuncture Department of the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, involving 70 dry eye patients. The patients were randomly divided into two groups: an acupuncture plus medication group (n = 35) and a medication-only group (n = 35). The acupuncture plus medication group received the Tiaoshen Runmu acupuncture method combined with artificial tears, while the medication-only group was treated with artificial tears alone. Treatment was administered once daily for two consecutive weeks. The Ocular Surface Disease Index (OSDI), Tear Film Breakup Time (BUT), Schirmer I Test (SIT), Fluorescein Staining (FL), and Tear Meniscus Height (TMH) were compared between the two groups to assess clinical efficacy. Results: Baseline levels of OSDI, BUT, SIT, FL, and TMH showed no significant differences between the two groups before treatment (P > 0.05). After treatment, OSDI scores in both groups decreased, with the acupuncture plus medication group showing significantly lower OSDI scores than the medication-only group (P < 0.05). BUT, SIT, FL, and TMH all improved significantly in both groups, with the acupuncture plus medication group showing greater improvements compared to the medication-only group (P < 0.05). The total clinical efficacy rate in the acupuncture plus medication group was significantly higher than that of the medication-only group (P < 0.05). Conclusion: The Tiaoshen Runmu acupuncture method combined with artificial tears is effective in improving the symptoms of dry eye disease, promoting tear secretion, and stabilizing tear film. The clinical efficacy is significantly better than artificial tears alone.
