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创伤性颅内出血患者下肢DVT发生的影响因素及Caprini评分的预测价值

The Influencing Factors of Lower Limb DVT Occurrence in Patients with Traumatic Intracranial Hemorrhage and the Clinical Value of Caprini Score in Predicting Lower Limb DVT Occurrence
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摘要 【目的】探讨创伤性颅内出血患者下肢深静脉血栓(DVT)发生的影响因素及Caprini评分预测患者下肢DVT发生的临床价值。【方法】选取2020年1月至2023年5月本院收治的126例创伤性颅内出血患者,根据下肢DVT发生情况将其分为DVT组(n=35)和非DVT组(n=91)。采用单因素及多因素Logistic回归方程分析下肢DVT影响因素,采用受试者工作特征(ROC)曲线分析Caprini评分预测患者下肢DVT发生的临床价值。【结果】DVT组Caprini评分及糖尿病、年龄、使用脱水药物所占比例高于非DVT组,住院时间长于非DVT组,格拉斯哥昏迷量表(GCS)评分低于非DVT组,差异有统计学意义(P<0.05)。Logistic多因素回归分析显示,GCS评分、Caprini评分、年龄、使用脱水药物、住院时间均为创伤性颅内出血患者发生下肢DVT的影响因素(P<0.05)。ROC曲线分析显示,Caprini评分预测患者下肢DVT发生的曲线下面积(AUC)为0.805,95%CI为0.662~0.801(P<0.05),预测的灵敏度为75.63%,特异性为66.21%,阳性预测值为49.2%,阴性预测值为86.1%。【结论】年龄、住院时间、使用脱水药物、GCS评分、Caprini评分均为创伤性颅内出血患者发生下肢DVT影响因素,根据影响因素及时采取有效措施预防下肢DVT发生具有重要意义。 【Objective】To investigate the influencing factors of lower limb deep venous thrombosis(DVT)in patients with traumatic intracranial hemorrhage and the clinical value of Caprini score in predicting the occurrence of lower limb DVT.【Methods】A total of 126 patients with traumatic intracranial hemorrhage admitted to our hospital from January 2020 to May 2023 were selected and divided into DVT group(n=35)and non-DVT group(n=91)according to the incidence of DVT in lower limbs.The influence factors of lower limb DVT were analyzed by univariate and multivariate Logistic regression equations,and the clinical value of Caprini score in predicting the occurrence of lower limb DVT was analyzed by receiver operating characteristic(ROC)curve.【Results】The proportion of Caprini score,age≥60 and use of dehydrating drugs in the DVT group was higher than that in the non-DVT group,and the hospital stay was longer than that in non-DVT group,and the GCS score was lower than that in the non-DVT group,with statistical significance(P<0.05).Logistic multivariate regression analysis showed that GCS score,Caprini score,age,use of dehydrating drugs,and length of stay were all influencing factors for DVT of lower limbs in patients with traumatic intracranial hemorrhage(P<0.05).ROC curve analysis showed that the area under the curve(AUC)predicted by Caprini score was 0.805,95%CI was 0.662~0.801(P<0.05),the sensitivity of prediction was 75.63%,the specificity is 66.21%,the positive predictive value was 49.2%,and the negative predictive value was 86.1%.【Conclusion】Age,length of stay,use of dehydrating agent,GCS score and Caprini score are all influencing factors for the occurrence of DVT in patients with traumatic intracranial hemorrhage.It is of great significance to take effective measures to prevent the occurrence of DVT in the lower extremity according to the influencing factors.
作者 丁应娟 严迪 赵梦洋 DING Yingjuan;YAN Di;ZHAO Mengyang(Xinyang People's Hospital,Xinyang Henan 464000)
机构地区 信阳市人民医院
出处 《医学临床研究》 2025年第1期49-52,共4页 Journal of Clinical Research
关键词 颅内出血 创伤性 静脉血栓形成 影响因素分析 Intracranial Hemorrhage,Traumatic Venous Thrombosis Root Cause Analysis

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